Acipimox

HCID 178903488

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기본 정보

CAS: 1246816-28-3
표준 SMILES: Cc1cnc(C(=O)O)c[n+]1[O-]
InChIKey: DJQOOSBJCLSSEY-UHFFFAOYSA-N
분자식: C6H6N2O3
평균 분자량: 154.12 g/mol

개요

5-methyl-4-oxido-2-pyrazin-4-iumcarboxylic acid is a pyrazinecarboxylic acid.

이름 및 식별자

우선 이름: Acipimox
IUPAC: 5-methyl-4-oxidopyrazin-4-ium-2-carboxylic acid
영어명: Acipimox-d4
분자식: C6H6N2O3
분자량: 154.12344

이름 및 동의어

ACIPIMOX51037-30-0OlbetamOlbemox5-methylpyrazine-2-carboxylic acid 4-oxide5-Methylpyrazinecarboxylic acid 4-oxide5-methyl-4-oxidopyrazin-4-ium-2-carboxylic acidDTXSID2046202NSC-759818K9AY9IR2SDDTXCID00262025-CARBOXY-2-METHYLPYRAZIN-1-IUM-1-OLATE

이름 더 보기

K 9321-d4OlbetaM-d4OlbeMox-d4Acipimox-d4[2H4]-Acipimox5-Methylpyrazinecarboxylic Acid 4-Oxide-d45-Methyl-2-pyrazinecarboxylic Acid 4-Oxide-d4

AcipimoxumRefChem:552678C10AD06256-928-35-Carboxy-2-methylpyrazine 1-oxideMFCD008657572-CARBOXY-5-METHYLPYRAZINE 4-OXIDEACIPIMOX [WHO-DD]

데이터베이스 식별자

CAS: 1246816-28-3
ChEMBL: CHEMBL345714
ChEBI: CHEBI:94688
UNII: K9AY9IR2SD
EC Number: 256-928-3
Nikkaji: J10.290C

물성

구조 계산 물성

XLogP: -1
극성 표면적: 75.7 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 4
회전 가능 결합 수: 1
무거운 원자 수: 11
형식 전하: 0
복잡도: 162

실험 및 물리화학적 성질

Drugs · 2건

Pharmaceuticals -> Antilipidemics

Pharmaceuticals -> Listed in ZINC15

물리화학적 성질

녹는점: 170 °C · >170°C (dec.)
저장 조건: -20 °C · -20°C Freezer
용해도: 메탄올(약간 용해됨), 물(약간 용해됨)
물리적 상태: 고체
색상: 미색부터 밝은 베이지까지

안전 및 규제

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 41.7% (30 of 72) of reports.

Warning

H319 (58.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)

Aggregated GHS information provided per 72 reports by companies from 3 notifications to the ECHA C&L Inventory.

유해성 정보

Hazard Classes and CategoriesEye Irrit. 2A (58.3%)

화학 및 산업

약리 정보

ATC Code · 3건

C10AD06

C - Cardiovascular system

QC - Cardiovascular system

Mechanism of ActionAcipimox inhibits the production of triglycerides by the liver and the secretion of VLDL, which leads indirectly to a modest reduction in LDL and increase in HDL.

MeSH Pharmacological ClassificationSubstances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.

응용 분야

용도Labelled antilipemic.

공급사7 곳

艾吉析科技（上海）有限公司17717235263 · [email protected]

凯试(上海)科技有限公司021-50135380 · [email protected]

常州翔龙医药科技有限公司18915873328 18915873328 · [email protected]

深圳振强药物研发有限公司+86-0755-66853366 +86-13670046396 · [email protected]

安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]

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