기본 정보
- CAS
127293-58-7- 표준 SMILES
OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1- InChIKey
GGUSQTSTQSHJAH-UHFFFAOYSA-N- 분자식
- C20H23ClFNO
- 평균 분자량
- 347.9 g/mol
개요
Eliprodil is a racemate comprising equimolar amounts of (R)- and (S)-eliprodil. It is a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist and an anti-ischaemic agent that exhibits neuroprotective properties. It has a role as a geroprotector, a calcium channel blocker, a NMDA receptor antagonist and a neuroprotective agent. It contains a (R)-eliprodil and a (S)-eliprodil.
이름 및 식별자
- 우선 이름
- Eliprodil
- IUPAC
- 1-(4-chlorophenyl)-2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]ethanol
- 현지명
- 엘리프로딜
- 영어명
- ELIPRODIL
- 분자량
- 0
이름 및 동의어
Eliprodil119431-25-3DTXSID1045744SL-820715YW62A6TW29DTXCID9025744CHEBI:917841-Piperidineethanol, alpha-(4-chlorophenyl)-4-(4-fluorophenyl)-, (+-)-1-(4-chlorophenyl)-2-{4-[(4-fluorophenyl)methyl]piperidin-1-yl}ethan-1-oleliprodilumSL 82.07151-(4-chlorophenyl)-2-(4-((4-fluorophenyl)methyl)piperidin-1-yl)ethan-1-ol
이름 더 보기
엘리프로딜A-(4-CHLOROPHENYL)-4-[(4-FLUOROPHENYL)METHYL]-1-PIPERIDINEETHANOL1-(4-CHLORO-PHENYL)-2-[4-(4-FLUORO-BENZYL)-PIPERIDIN-1-YL]-ETHANOL1-PIPERIDINEETHANOL, A-(4-CHLOROPHENYL)-4-[(4-FLUOROPHENYL)METHYL]-
1-(4-chlorophenyl)-2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]ethan-1-ol(4-chlorophenyl)-4-((4-fluorophenyl)methyl)-1-piperidineethanolRefChem:590714Eliprodil [INN]C20H23ClFNO1-(4-chlorophenyl)-2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]ethanolalpha-(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanolMFCD00866651
데이터베이스 식별자
- CAS
127293-58-7
물성
구조 계산 물성
- XLogP
- 4.5
- 극성 표면적
- 23.5 Ų
- 수소 결합 공여자 수
- 1
- 수소 결합 수용자 수
- 3
- 회전 가능 결합 수
- 5
- 무거운 원자 수
- 24
- 형식 전하
- 0
- 복잡도
- 359
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
Warning
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
P264+P265, P273, P280, P305+P351+P338, P337+P317, P391, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 38 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Hazard Classes and CategoriesEye Irrit. 2 (100%)
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists.
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
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