기본 정보
- CAS
1431868-11-9- 표준 SMILES
[15NH2][13C@@H]([13CH2][13c]1[13cH][13c](I)[13c](Oc2cc(I)c(O)c(I)c2)[13c](I)[13cH]1)[13C](=O)O- InChIKey
XUIIKFGFIJCVMT-LPIUGHGLSA-N- 분자식
- C15H11I4NO4
- 평균 분자량
- 786.8 g/mol
이름 및 식별자
- 우선 이름
- Fluphenazine N4'-oxide
- IUPAC
- (2S)-2-(15N)azanyl-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo(1,2,3,4,5,6-13C6)cyclohexa-1,3,5-trien-1-yl](1,2,3-13C3)propanoic acid
- 영어명
- L-Thyroxine-13C9,15N
- 분자식
- C15H11I4NO4
- 분자량
- 786.8
이름 및 동의어
1431868-11-9Fluphenazine N4'-oxideL-Thyroxine-13C9,15NLevothyroxine-13C9-15NL-Thyroxine-13C6,15N(2S)-2-(15N)azanyl-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo(1,2,3,4,5,6-13C6)cyclohexa-1,3,5-trien-1-yl](1,2,3-13C3)propanoic acid4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol 1-OxideO-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine-carboxy,alpha,beta,1,2,3,4,5,6-13C9-15NThyroxine Carboxy,?,?,1,2,3,4,5,6-13C9,15NC15H11I4NO4orb1693785AKOS040755227
이름 더 보기
Thyroxine Carboxy,α,β,1,2,3,4,5,6-13C9,15NThyroxine Carboxy,alpha,beta,1,2,3,4,5,6-13C9,15NO-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine-carboxy,α,β,1,2,3,4,5,6-13C9-15N
HY-18341S3CS-0638230T36383(2S)-2-(15N)azanyl-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-(1,2,3,4,5,6-13C6)cyclohexa-1,3,5-trien-1-yl](1,2,3-13C3)propanoic acid
데이터베이스 식별자
물성
구조 계산 물성
- XLogP
- 2.4
- 극성 표면적
- 92.8 Ų
- 수소 결합 공여자 수
- 3
- 수소 결합 수용자 수
- 5
- 회전 가능 결합 수
- 5
- 무거운 원자 수
- 24
- 형식 전하
- 0
- 복잡도
- 420
물리화학적 성질
- 밀도
- 2.636 · 2.636±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- 저장 조건
- -20 °C · Store at -20°C
- 용해도
- 0.14 mg/ml; · DMF: 0.14 mg/ml; DMSO: 2.5 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml
- 물리적 상태
- 고체
화학 및 산업
응용 분야
개요L-Thyroxine-13C9,15N is intended for use as an internal standard for the quantification of L-thyroxine by GC- or LC-MS. L-Thyroxine is a synthetic form of the thyroid hormone thyroxine. In vivo, L-thyroxine (0.9 and 2.7 μg) inhibits synthesis and release of thyrotropin induced by thyrotropin-releasing hormone from the anterior pituitary in mice. It also reverses decreases in levels of circulating thymic serum factor (FTS) and the number of T rosette-forming cells in an old age-induced mouse model of hypothyroidism. Formulations containing L-thyroxine have been used in the treatment of hypothyroidism.
용도Thyroxine Carboxy,α,β,1,2,3,4,5,6-13C9,15N is 13C and 15N labeled analogue of Thyroxine (T425600), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis.
공급사7 곳
上海稳同科技有限公司02151600108 13062666369 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海宏叶生物科技有限公司400-9205774 400-920-5774 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
ChemeGen 中国18818260767 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
TLC梯尔希（南京）药物研发有限公司18012923235 · [email protected]
관련 반응
0건
현재 필터 조건에 해당하는 반응 기록이 없습니다.
화합물 노트
불러오는 중…