Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(트리클로로메틸)옥시란
(트리클로로메틸)옥시란 · TRICHLOROPROPANEOXIDE · Trichloroepoxypropane · TRICHLOROPROPYLENEOXIDE · (trichloromethyl)oxirane · Oxirane, 2-(trichloromethyl)- · 3,3,3-TRICHLOROPROPYLENEOXIDE · 1,1,1-TRICHLORO-2,3-EPOXYPROPANE
식별자 및 물리적 특성
| CAS No. | 3083-23-6 |
|---|---|
| 분자식 | C3H3Cl3O |
| 평균 분자량 | 161.41 g/mol |
| 단동위원소 질량 | 159.924948 g/mol |
| SMILES | ClC(Cl)(Cl)C1CO1 |
| InChIKey | VFEXYZINKMLLAK-UHFFFAOYSA-N |
| PubChem CID | 18321 |
| EC No. | 221-384-8 |
| DTXSID | DTXSID3025251 |
| 현지명 | (트리클로로메틸)옥시란 |
화학 및 물리적 성질
| XLogP | 1.8 |
|---|---|
| 극성 표면적 | 12.5 |
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 1 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 7 |
| 형식 전하 | 0 |
| 복잡도 | 76 |
| 밀도 | 1.495 at 68 °F (NTP, 1992) - Denser than waterwill sink1.4950 |
| 용해도 | less than 0.1 mg/mL at 65.3 °F (NTP, 1992) |
| 인화점 | 152 °F (NTP, 1992) |
| 끓는 점 | 300 °F at 764 mmHg (NTP, 1992)226.05°C (rough estimate) |
| 증기압 | 11.6 mmHg at 77 °F28.5 mmHg at 108 °F65.5 mmHg at 149 °F (NTP, 1992)11.6 [mmHg] |
| Physical Description | 1,2-epoxy-3,3,3-trichloropropane is a clear colorless liquid. (NTP, 1992)Clear colorless liquid[CAMEO] |
| Kovats Retention Index | 885 |
| 굴절률 | 1.4737 (estimate) |
| 안정성 | 안정적인. 타기 쉬운. 강한 산화제와 호환되지 않습니다. |
| EPA | 1,1,1-Trichloro-2,3-epoxypropane (3083-23-6) |
화학적 성질
colourless liquid
안전 및 규제
| GHS 분류 | WarningH226 (100%): Flammable liquid and vapor [Warning Flammable liquids]H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]H373 (100%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]P203, P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P317, P318, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. |
|---|---|
| 화재 위험 | This chemical is combustible. (NTP, 1992) |
| 건강 유해성 | ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes. (NTP, 1992) |
| 유해성 요약 | Intraperitoneal LD50 (rat) = 142 mg/kg[RTECS] Enhances the tumor initiating ability of some carcinogens[ChemIDplus] Highly flammable and polymerizable[CAMEO] See Epibromohydrin and Epichlorohydrin. |
| 반응성 그룹 | Halogenated Organic CompoundsEpoxidesPolymerizable Compounds |
| Reactivity Alerts | Polymerizable |
| Reactivity Profile | Epoxides are highly reactive. They polymerize in the presence of catalysts or when heated. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts. |
| Air and Water Reactions | Insoluble in water. |
| Hazard Classes and Categories | Flam. Liq. 3 (100%)Acute Tox. 4 (100%)Skin Irrit. 2 (100%)Eye Irrit. 2 (100%)STOT SE 3 (100%)Carc. 2 (100%)STOT RE 2 (100%) |
| 소화 | Fires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992) |
| 응급 처치 | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.INHALATION: IMMEDIATELY leave the contaminated areatake deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be usedif not available, use a level of protection greater than or equal to that advised under Protective Clothing.INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992) |
| 비화재 누출 대응 | SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.STORAGE PRECAUTIONS: You should store this material in a refrigerator. STORE AWAY FROM SOURCES OF IGNITION. (NTP, 1992) |
| Personal Protective Equipment (PPE) | RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992) |
| 독성 | mmo-sat 740 mg/plate APSXAS 17,189,80 |
용도
용도
Trichloropropene Oxide is a epoxide hydratase inhibitor and possess potential carcinogenic properties.
일반 설명
Clear colorless liquid.