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Aspon

HCID 18609
노트반응
기본 정보이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
3244-90-4
표준 SMILES
CCCOP(=S)(OCCC)OP(=S)(OCCC)OCCC
InChIKey
IIDFEIDMIKSJSV-UHFFFAOYSA-N
분자식
C12H28O5P2S2
평균 분자량
378.4 g/mol
단동위원소 질량
378.08534033

이름 및 식별자

우선 이름
Aspon
IUPAC
dipropoxyphosphinothioyloxy-dipropoxy-sulfanylidene-λ5-phosphane
영어명
ASPON (TM)
분자식
C12H28O5P2S2
분자량
378.43

이름 및 동의어

ASPON3244-90-4Stauffer asp-51Tetra-n-propyl dithiopyrophosphateO,O,O,O-Tetrapropyl dithiopyrophosphateASP 51Caswell No. 845ATetrapropyldithiodifosfatTetrapropyl dithiopyrophosphateENT 16,894Tetrapropyl thiodiphosphateNSC 2550
이름 더 보기
a42e8573ASP-51NSC2550NSC-2550ent16,894ASPON (TM)staufferasp-51
E 8573HSDB 1776Tetrapropyldithiodifosfat [Czech]Thiopyrophosphoric acid, tetrapropyl esterTetrapropyl thiopyrophosphateEINECS 221-817-0UNII-PC55IL137PEPA Pesticide Chemical Code 079101

데이터베이스 식별자

CAS
3244-90-4
PubChem CID
18609
DTXSID
DTXSID6032510
UNII
PC55IL137P
EC Number
221-817-0
Nikkaji
J7.697J

물성

구조 계산 물성

XLogP
6
극성 표면적
110 Ų
수소 결합 공여자 수
0
수소 결합 수용자 수
7
회전 가능 결합 수
14
무거운 원자 수
21
형식 전하
0
복잡도
299

실험 및 물리화학적 성질

Pesticides · 2건

Pesticides -> Organophosphate Insecticides

Pesticide (Aspon) -> USDA PDB

OdorTechnical product (93-96% pure) has a faint aromatic odor.
DensityDensity at 20 °C/20 °C = 1.119-1.123 (Technical product, 93-96% pure)
Color/FormTechnical product (93-96% pure) is a straw to amber-colored liquid.
Solubility · 3건

FP: BELOW 5 °C; SPARINGLY SOL IN LIGHT PETROLEUM; MISCIBLE WITH MOST ORGANIC SOLVENTS /TECHNICAL PRODUCT/

Solubility in water at 20 °C is 30 mg/l water (Technical product, 93-96% pure).

Miscible with acetone, ethanol, kerosene, 4-methylpentan-2-one, xylene (Technical product, 93-96% pure)

CorrosivityCorrosive to steel (Technical product, 93-96% pure)
Flash Point · 2건

149 °C

149 °C (OPEN CUP) /TECHNICAL PRODUCT/

Boiling Point170 °C at l.0 mm Hg (Technical product, 93-96% pure)
Vapor Pressure · 2건

0.0000107 [mmHg]

The vapor pressure at 25 °C is 13 mPa (Technical product, 93- 96% pure)

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 6건

Warning

H302: Harmful if swallowed [Warning Acute toxicity, oral]

P264, P270, P273, P280, P301+P317, P302+P352, P317, P321, P330, P362+P364, P391, and P501 (click each P-code to see the statement)

Warning

H302+H312 (92.9%): Harmful if swallowed or in contact with skin [Warning Acute toxicity, oral; acute toxicity, dermal]

P264, P270, P273, P280, P301+P317, P302+P352, P317, P321, P330, P362+P364, P391, and P501 (click each P-code to see the statement)

유해성 정보

Hazards Summary · 1건

Depressed cholinesterase activity in 90-day feeding study of rats at doses below lethal levels; Showed no evidence of mutagenicity; [HSDB] Effects in high-dose animal studies include convulsions and inhibition of true cholinesterase; [RTECS] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

FIFRA Requirements · 1건

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Aspon is found on List A, which contains most food use pesticides and consists of the 194 chemical cases (or 350 individual active ingredients) for which EPA issued registration standards prior to FIFRA, as amended in 1988. Case No: 0019; Pesticide type: Insecticide; Registration Standard Date: 09/01/80; Case Status: No products containing the pesticide are actively registered ... The case /is characterized/ as "cancelled." Under FIFRA, pesticide producers may voluntarily cancel their registered products. EPA also may cancel pesticide registrations if registrants fail to pay required fees or make/meet certain reregistration commitments, or if EPA reaches findings of unreasonable adverse effects.; Active ingredient (AI): Aspon; AI Status: The active ingredient is no longer contained in any registered pesticide products ... "cancelled."

화학 및 산업

약리 정보

Mechanism of ActionPARATHION & ITS RELATIVES ARE KNOWN TO INHIBIT ENZYME CHOLINESTERASE IN ALL PARTS OF THE BODY BY PHOSPHORYLATING THE ACTIVE SITE. /PARATHION/

용도 및 제조

Uses · 6건

Used as insecticide and acaricide to protect lawns and turf; [HSDB]

Cancelled--no longer registered as a pesticide for use in the US; [HSDB]

Farming (Pesticides) [Category: Industry]

The active ingredient is no longer contained in any registered pesticide products ... "cancelled."

INSECTICIDE /FORMER USE/

ACARICIDE /FORMER USE/

U.S. Exports · 2건

(1972) No Data

(1975) No Data

U.S. Imports · 2건

(1972) No Data

(1975) No Data

U.S. Production(1974) 2.27X10+8 G (CONSUMPTION)
Consumption PatternsESSENTIALLY 100% AS AN INSECTICIDE FOR SOD WEBWORMS & CINCHBUGS ON LAWN & TURF
Methods of ManufacturingREACTION OF O,O-DI-N-PROPYL PHOSPHOROCHLORIDOTHIOATE WITH WATER, IN THE PRESENCE OF PYRIDINE
Formulations/Preparations · 4건

'ASPON', EMULSIFIABLE CONCENTRATE (480 G ACTIVE INGREDIENT/L); GRANULES (50 G/KG).

WETTABLE POWDER (25%); EMULSIFIABLE CONCENTRATE (85%), (6 LB/GAL)...

Technical product is 93-96% pure.

'Aspon E', EC(240 or 720 g a.i./l); 'Aspon 5GA', 'Aspon 25G', Aspon 25G', GR(50 or 250 g/kg)

General Manufacturing Information · 3건

/IT IS/...PROTECTED BY US PATENT 2663722.

COMPATIBLE WITH COMMONLY-USED PEST CONTROL MATERIALS. CONSIDERABLE CONTACT & FUMIGANT INSECTICIDAL PROPERTY, ESPECIALLY AGAINST APHIDS--SOME RESIDUAL ACTIVITY. ACTIVE AGAINST CINCH BUGS, BLISSUS SPECIES, IN EASTERN USA. RECOMMENDED FOR USE ON TURF. NO PHYTOXICITY REPORTED AT INSECTICIDAL CONCENTRATIONS.

관련 반응

0건
반응 기록 만들기

현재 필터 조건에 해당하는 반응 기록이 없습니다.

화합물 노트

불러오는 중…

이 페이지에서기본 정보이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
Refractive IndexIndex of refraction is 1.471 at 21 °C/D (Technical product, 93-96% pure).
Physical DescriptionStraw to amber-colored liquid; [HSDB] Amber liquid; [MSDSonline]
Stability/Shelf LifeSTABLE WITH INSIGNIFICANT HYDROLYSIS IN WATER AT ROOM TEMP; STABLE FOR AT LEAST 24 HR @ 100 °C, BUT DECOMP, WITHOUT EXPLOSIVE HAZARD @ 149 °C; DISCOLORATION & PHYSICAL CHANGES MAY OCCUR ON PROLONGED CONTACT WITH METAL /TECHNICAL/

물리화학적 성질

녹는점
-44.9 °C · -44.9°C
끓는 점
381.6 · 381.6±25.0 °C(Predicted)
밀도
1.12 · 1.1200
인화점
149 °C · 149 °C
물리적 상태
액체
Henry's Law Constant
6.1 · 6.1×100 mol/(m3Pa) at 25℃, Ebert et al. (2023)
EPA
Tetrapropyl dithiopyrophosphate (3244-90-4)

화학적 성질

ASPON (TM) is amber liquid. Miscible with most organic solvents; insoluble in water.

Hazard Classes and Categories · 3건

Acute Tox. 4 (100%)

Acute toxicity - category 4

Acute Tox. 4 *

안전 및 보호

Exposure Control and Personal Protection · 1건

Biological Exposure Indices (BEI) [ACGIH] - Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

Disposal Methods · 1건

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

독성 정보

Adverse EffectsOther Poison - Organophosphate
Human Toxicity Excerpts · 2건

SYMPTOMATOLOGY: 1. NAUSEA...VOMITING, ABDOMINAL CRAMPS, DIARRHEA, EXCESSIVE SALIVATION... 2. HEADACHE, GIDDINESS, VERTIGO & WEAKNESS. 3. RHINORRHEA & SENSATION OF TIGHTNESS IN CHEST ARE COMMON IN INHALATION EXPOSURE. 4. BLURRING OR DIMNESS OF VISION, MIOSIS... TEARING, CILIARY MUSCLE SPASM, LOSS OF ACCOMMODATION & OCULAR PAIN... MYDRIASIS...SOMETIMES SEEN...PROBABLY DUE TO SYMPATHO-ADRENAL DISCHARGE. 5. LOSS OF MUSCLE COORDINATION, SLURRING OF SPEECH, FASCICULATIONS & TWITCHING OF MUSCLES (PARTICULARLY OF TONGUE & EYELIDS), & GENERALIZED PROFOUND WEAKNESS. 6. MENTAL CONFUSION, DISORIENTATION & DROWSINESS. /PARATHION/

SYMPTOMATOLOGY: 7. DIFFICULTY IN BREATHING, EXCESSIVE SECRETION OF SALIVA & OF RESP TRACT MUCUS, ORONASAL FROTHING, CYANOSIS, PULMONARY RALES & RHONCHI & HYPERTENSION, (PRESUMABLY DUE TO ASPHYXIA). 8. RANDOM JERKY MOVEMENTS, INCONTINENCE, CONVULSIONS, & COMA. 9. DEATH PRIMARILY DUE TO RESP ARREST ARISING FROM FAILURE OF RESP CENTER, PARALYSIS OF RESP MUSCLES, INTENSE BRONCHOCONSTRICTION OR ALL THREE. /PARATHION/

Non-Human Toxicity Excerpts · 3건

IN 90-DAY FEEDING TRIALS AT SUBLETHAL RATES RATS SHOWED DEPRESSION OF RED BLOOD CELL CHOLINESTERASE.

REPORTED TO BE ANTICHOLINESTERASE OF LOW MAMMALIAN TOXICITY. ...GROWTH OF RATS GIVEN /ORALLY/ 25 MG/KG DAILY IS INHIBITED.

FOURTEEN PESTICIDES INCL ASPON WERE EVALUATED FOR MUTAGENIC POTENTIAL. THE MICROBIAL ASSAY SYSTEMS USED WERE THE HISTIDINE REVERSE MUTATION SYSTEM IN 5 STRAINS OF SALMONELLA TYPHIMURIUM (TA1535, TA1537, TA1538, TA98, & TA100), THE TRYPOTPHAN MUTATION SYSTEM IN ESCHERICHIA COLI WP2, & THE MITOTIC RECOMBINATION ASSAYS IN SACCHAROMYCES CEREVISIAE D3. A MAMMALIAN METABOLIC ACTIVATION SYSTEM USING LIVER OF RATS THAT HAD BEEN TREATED WITH AROCLOR 1254 WAS USED IN ALL ASSAYS. ASPON WAS NONMUTAGENIC. RESULTS OF OTHER CHEMICALS ARE GIVEN.

규제 정보

FIFRA Requirements · 1건

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Aspon is found on List A, which contains most food use pesticides and consists of the 194 chemical cases (or 350 individual active ingredients) for which EPA issued registration standards prior to FIFRA, as amended in 1988. Case No: 0019; Pesticide type: Insecticide; Registration Standard Date: 09/01/80; Case Status: No products containing the pesticide are actively registered ... The case /is characterized/ as "cancelled." Under FIFRA, pesticide producers may voluntarily cancel their registered products. EPA also may cancel pesticide registrations if registrants fail to pay required fees or make/meet certain reregistration commitments, or if EPA reaches findings of unreasonable adverse effects.; Active ingredient (AI): Aspon; AI Status: The active ingredient is no longer contained in any registered pesticide products ... "cancelled."

안전 데이터

rtecs
XN4550000
ridadr
3018
독성
Acute oral LD50 for rats 450 mg/kg (RTECS, 1985).
risk_code
21/22-50/53
hazard_code
Xn,N
safety_code
36/37-60-61
포장분류
III
위험 등급
6.1(b)
유해 물질 데이터
3244-90-4(Hazardous Substances Data)

Aspon's registration has been cancelled

응용 분야

용도ASPON (TM) is an organophosphorus, nonsystemic insecticide used to control chinch bugs in lawns

공급사15 곳

武汉易泰科技有限公司上海分公司18930552037 · [email protected]
安耐吉化学&3A(安徽泽升科技有限公司)021-58432009 400-005-6266 · [email protected]
梯希爱(上海)化工贸易有限公司021-61109150 · [email protected]
上海毕楷科技有限公司18516304666 · [email protected]
天津阿尔塔科技有限公司022-65378550-8551 · [email protected]
天津阿尔塔科技有限公司022-6537-8550 15522853686 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
深圳聚合生化科技有限公司+86-400-002-6226 13028896684 · [email protected]
爆牛贸易重庆有限公司+86-023-6139-8061 +86-86-13650506873 · [email protected]
陕西缔都医药化工有限公司029-029-029-81148696 18161915376 · [email protected]
上海安谱实验科技股份有限公司18502138905 · [email protected]
北京百灵威科技有限公司18210857532 18210857532 · [email protected]
DAYANG CHEM (HANGZHOU) CO.,LTD+86-88938639 +86-17705817739 · [email protected]
TargetMol中国(陶术生物)15002134094 · [email protected]