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개요Formic acid is a clear, colorless liquid with a pungent odor. Formic acid was first isolated from certain ants and was named after the Latin formica, meaning ant. It is made by the action of sulfuric acid on sodium formate, which is produced from carbon monoxide and sodium hydroxide. It is also produced as a by-product in the manufacture of other chemicals such as acetic acid. It can be anticipated that use of formic acid will continuously increase as it replaces inorganic acids and has a potential role in new energy technology. Formic acid toxicity is of a special interest as the acid is the toxic metabolite of methanol.
출처Widespread in a large variety of plants; reported identifed in Cistus labdanum and the oil of Artemisia trans- iliensis; also found among the constituents of petit grain lemon and bitter orange essential oil; reported found in strawberry aroma Reported found in apple, sweet cherry, papaya, pear, raspberry, strawberry, peas, cheeses, breads, yogurt, milk, cream, buttermilk, raw fsh, cognac, rum, whiskey, cider, white wine, tea, coffee and roasted chicory root
역사Formic acid is taken from the Latin word forant, formica. Naturalists had observed the acrid vapor from ant hills for hundreds of years. One of the earliest descriptions of formic acid was reported in an extract of a letter written from John Wray (1627–1705) to the publisher of Philosophical Transactions published in 1670. Wray’s letter reported on “uncommon Observations and Experiments made with an Acid Juyce to be Found in Ants” and noted the acid was previously obtained by Samuel Fisher from the dry distillation of wood ants. Formic acid is found in stinging insects, plants, unripe fruit, foods, and muscle tissue. Jns Jacob Berzelius (1779–1848) characterized formic acid in the early 19th century, and it wasfirst synthesized from hydrocyanic acid by Joseph Louis Gay-Lussac (1778–1850) at about the same time. A number of synthetic preparations of formic acid were found in the first half of the 19th century. Marcellin Berthelot (1827–1907) discovered a popular synthesis using oxalic acid and glycerin in 1856; he and several other chemists from his period found syntheses of formic acid by heating carbon monoxide in alkaline solutions.
일반 설명Formic acid is the simplest carboxylic acid. Crystal structure study by single-crystal X-ray diffraction technique at -50°C has shown that it has an orthorhombic structure with space group Pna. The photodegradation of formic acid has been investigated using ab intio calculations and time-resolved Fourier transform infrared spectroscopy. Its utility as a fuel in direct fuel cells has been studied. The momentum distribution for its monomer have been evaluated by electron momentum spectroscopy (EMS).
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Formic acid, or methanoic acid, is the first member of the homologous series identified as fatty acids with the general formula RCOOH. Formic acid was obtained first from the red ant; itscommon name is derived from the family name for ants, Formicidae. This substance also occurs naturally in bees and wasps, and is presumed to be responsible for the "sting" of these insects. Formic acid has a pungent, penetrating odor. It may be synthesized from anhydrous sodium formate and concentrated H2S04 at low temperature followed by distillation.
생산 방법Formic acid is manufactured as a by-product of the liquidphase oxidation of hydrocarbons to acetic acid. It is also produced by (a) treating sodium formate and sodium acid formate with sulfuric acid at low temperatures followed by distillation or (b) direct synthesis from water and CO2 under pressure and in the presence of catalysts.
순도시험(1) 초산 : 이 품목 1mL(약 1.2g에 해당하는 양)에 물을 가하여 100mL로 하고 이 액 50mL를 취하여 250mL 증류플라스크에 넣고 황색의 산화제이수은 5g을 가한다. 환류냉각기를 부착한 다음 2시간 동안 계속 저으면서 끓이고 식힌 후 여과하고 잔류물은 물 25mL로 씻고 씻은 액은 여액과 합치고 페놀프탈레인시액을 지시약으로 하여 0.02N 수산화나트륨용액으로 적정할 때, 그 소비량은 2.0mL 이하이어야 한다. (2) 희석시험 : 이 품목 1용량을 물 3용량에 희석하였을 때, 1시간 내에 혼탁해져서는 아니 된다. (3) 황산염 : 이 품목 2.4g에 탄산나트륨 약 10mg을 가한 다음 수욕상에서 증발건고하고 잔류물을 취하여 황산염시험법에 따라 시험할 때, 그 양은 0.01N 황산 0.2mL에 대응하는 양 이하이어야 한다. (4) 납 : 이 품목 5.0g을 취하여 원자흡광광도법 또는 유도결합플라즈마발광광도법에 따라 시험할 때, 그 양은 2.0ppm 이하이어야 한다.
확인시험이 품목 5mL에 염화제이수은시액 2mL를 가하여 가온하면 백색의 염화제일수은결정이 생긴다.
정량법물 15mL가 들어있는 마개가 달린 삼각플라스크의 무게를 단 다음 이 품목 1.5mL를 가하여 다시 무게를 단다. 이 액에 물을 넣어 50mL로 하고 1N 수산화나트륨용액으로 적정한다(지시약 : 페놀프탈레인시액).1N 수산화나트륨용액 1mL = 46.03mg CH2O2
정의ChEBI: Formic acid is the simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects. It has a role as an antibacterial agent, a protic solvent, a metabolite, a solvent and an astringent. It is a conjugate acid of a formate.