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나FENOPIN

Nafenopin

HCID 19592
노트반응
기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
3771-19-5
표준 SMILES
CC(C)(Oc1ccc(C2CCCc3ccccc32)cc1)C(=O)O
InChIKey
XJGBDJOMWKAZJS-UHFFFAOYSA-N
분자식
C20H22O3
평균 분자량
310.4 g/mol
단동위원소 질량
310.15689456

개요

Nafenopin can cause cancer according to an independent committee of scientific and health experts.

이름 및 식별자

우선 이름
Nafenopin
IUPAC
2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid
현지명
나FENOPIN
영어명
Nafenopin
분자식
C20H22O3
분자량
310.39

이름 및 동의어

Nafenopin3771-19-5MelipanNafenoic acidTPIANafenopineSU-13437NafenopinumDTXSID8020911Ciba 13437 SUnafenopinaCH 13437
이름 더 보기
나FENOPIN나페노핀나페노핀(NAFENOPIN)C-13437SuCIBA-13437SuNafenopin USP/EP/BP2-methyl-2-(4-tetralin-1-ylphenoxy)propionic acid2-METHYL-2-PARA-(1,2,3,4-TETRAHYDRO-1-NAPHTHYL)PHENOXYPROPIONICACID2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoicaci
C 13437 SUSU 13437CH 13-437093W78U96W2-Methyl-2-(p-(1,2,3,4-tetrahydro-1-naphthyl)phenoxy)propionic acidDTXCID40911Propanoic acid, 2-methyl-2-(4-(1,2,3,4-tetrahydro-1-naphthalenyl)phenoxy)-2-Methyl-2-(4-(1,2,3,4-tetrahydro-1-naphthalenyl)phenoxy)propanoic acid

데이터베이스 식별자

CAS
3771-19-5
PubChem CID
19592
DTXSID
DTXSID8020911
ChEMBL
CHEMBL1909070

물성

구조 계산 물성

XLogP
4.9
극성 표면적
46.5 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
3
회전 가능 결합 수
4
무거운 원자 수
23
형식 전하
0
복잡도
409

실험 및 물리화학적 성질

Melting Point243 to 244 °F (NTP, 1992)
Physical DescriptionCrystals. (NTP, 1992)

물리화학적 성질

녹는점
117 · 117-118 °C
끓는 점
390.55 °C · 390.55°C (rough estimate)
밀도
1.1662 · 1.1662 (rough estimate)
굴절률
1.4618 · 1.4618 (estimate)
저장 조건
Sealed in dry,Room Temperature
산도 계수 (pKa)
3.28 · 3.28±0.10(Predicted)
EPA
Nafenopin (3771-19-5)

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

유해성 정보

Regulatory InformationHazard Traits - Carcinogenicity
Fire HazardsFlash point data for this chemical are not available. It is probably combustible. (NTP, 1992)
Health HazardsSYMPTOMS: Symptoms of exposure to this chemical include a decrease of serum triglycerides.
Reactive GroupAcids, Carboxylic
Reactivity Profile · 1건

An organic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry. Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in it to corrode or dissolve iron, steel, and aluminum parts and containers. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. The reaction is slower for dry, solid carboxylic acids. Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. A wide variety of products is possible.

Air and Water Reactions

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 2건

Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.

A class of nongenotoxic CARCINOGENS that induce the production of hepatic PEROXISOMES and induce hepatic neoplasms after long-term administration.

응용 분야

일반 설명Crystals.

공급사20 곳

Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
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관련 반응

0건
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화합물 노트

불러오는 중…

이 페이지에서기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
ChEBI
CHEBI:77649
UNII
093W78U96W
Nikkaji
J8.248A
No rapid reaction with air. No rapid reaction with water.

안전 및 보호

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1건

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1건

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992)

독성 정보

Carcinogen Classification · 5건

Nafenopin

Group 2B: Possibly carcinogenic to humans

Volume 24: (1980) Some Pharmaceutical Drugs

1987

1987

안전 데이터

신호 어
Warning
유해·위험 문구
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드 H302
+86-29-81139210 +86-17392587031 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
艾琪康医药科技(上海)有限公司13512160998; 13512160998 · [email protected]
南通全益生物科技有限公司+86-0513; 18051384581 · [email protected]
艾览(上海)化工科技有限公司400-668-9898 · [email protected]
成都圣美凯生物科技有限公司028-85157043 15882256948 · [email protected]
TargetMol中国(陶术生物)4008200310 15002144251 · [email protected]
上海相辉医药科技有限公司13611835272 13611835272 · [email protected]
江苏艾康生物医药研发有限公司17714375163 · [email protected]
合肥钼凯医药科技有限公司18001872185; 18001872185 · [email protected]
InvivoChem+1-708-310-1919 +1-13798911105 · [email protected]

추가 설명

정의ChEBI: A monocarboxylic acid that is 2-hydroxy-2-methylpropanoic acid in which ther tertiary hydroxy group has been converted to the corresponding p-(1,2,3,4-tetrahydronaphthalen-1-yl)phenyl ether.