기본 정보
- CAS
3810-74-0- 표준 SMILES
CN[C@@H]1[C@H](O[C@H]2[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](N=C(N)N)[C@@H](O)[C@@H]3N=C(N)N)O[C@@H](C)[C@]2(O)C=O)O[C@@H](CO)[C@H](O)[C@H]1O.CN[C@@H]1[C@H](O[C@H]2[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](N=C(N)N)[C@@H](O)[C@@H]3N=C(N)N)O[C@@H](C)[C@]2(O)C=O)O[C@@H](CO)[C@H](O)[C@H]1O.O=S(=O)(O)O.O=S(=O)(O)O.O=S(=O)(O)O- InChIKey
QTENRWWVYAAPBI-YCRXJPFRSA-N- 분자식
- C42H84N14O36S3
- 평균 분자량
- 1,457.4 g/mol
- 단동위원소 질량
- 1,456.4334786
개요
Streptomycin Sulfate can cause developmental toxicity according to state or federal government labeling requirements.
이름 및 식별자
- 우선 이름
- Streptomycin Sulfate
- IUPAC
- bis(2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine);sulfuric acid
- 현지명
- 황산 스트렙토마이신
- 영어명
- Streptomycin sulfate
- 분자식
- C21H41N7O16S
- 분자량
- 679.65
이름 및 동의어
Streptomycin sulfateStreptomycin sulphate3810-74-0StrepcinStrycinVetstrepAmbistryn SAgri-StrepAgrimycin sulfateAgrimycin 17Streptomycin A sulfateStreptorex
이름 더 보기
황산스트렙토마이신황산스트렙토마이신염황산스트렙토마이신염(STREPTOMYCINSULFATESALT)Streptomycin Sulphate SterileStreptoStreptoMycin sulfatStreptomycine sulphateplantomycinEstreptomicinaSTREPTOMYCIN SULFATE SALTSTREPTOMYCIN SESQUISULFATE
AgristrepStrep-granStreptomycin (as sulfate)CW25IKJ202Streptomycin sulfate (2:3) (salt)CHEBI:32158AS-15Streptomycini sulfas
데이터베이스 식별자
- CAS
3810-74-0- PubChem CID
- 19648
- ChEMBL
물성
구조 계산 물성
- 극성 표면적
- 922 Ų
- 수소 결합 공여자 수
- 30
- 수소 결합 수용자 수
- 42
- 회전 가능 결합 수
- 18
- 무거운 원자 수
- 95
- 형식 전하
- 0
- 복잡도
- 1,020
실험 및 물리화학적 성질
Solubilitygreater than or equal to 0.1 mg/mL at 64 °F (NTP, 1992)
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Animal DrugsFDA approved animal drugs -> Active ingredient
Physical DescriptionStreptomycin sulfate (2:3) (salt) appears as an antibacterial. White to light gray or pale buff powder with faint amine-like odor.
물리화학적 성질
- 녹는점
- 185 °C · >185°C (dec.)
- 밀도
- 1.2302 · 1.2302 (rough estimate)
- 굴절률
- -85 ° · -85 ° (C=1, H2O)
- 저장 조건
- 2 · 2-8°C
- 용해도
- 2 O: · H2O: 0.1 g/mL, 투명
- 물리적 상태
- 가루
- 색상
- 흰색에서 황백색까지
- 수소이온지수(pH)
- pH (100g/l, 25℃) : 4.5～7.0
- 수용성
- 18 · 18&C에서 >=0.01g/100mL
- Merck
- 14 · 14,8826
- BRN
- 3894995 · 3894995
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 0.3% (1 of 303) of reports.
Danger
H302 (43.9%): Harmful if swallowed [Warning Acute toxicity, oral]
P203, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P330, P333+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 303 reports by companies from 22 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Regulatory Information
Chemical: D-Streptamine, O-2-deoxy-2-(methylamino)-.alpha.-L-glucopyranosyl-(1.fwdarw.2)-O-5-deoxy-3-C-formyl-.alpha.-L-lyxofuranosyl-(1.fwdarw.4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3)(salt)
Hazard Traits - Developmental Toxicity
Streptomycin Sesquisulfate is listed in the dataset of EPA Human Health Benchmarks for Pesticides under the Safe Drinking Water Act (40 eCFR 141)
Streptomycin sesquisulphate: Does not have an individual approval but may be used under an appropriate group standard
Fire HazardsFlash point data for this chemical are not available, however it is probably combustible. (NTP, 1992)
Health HazardsSYMPTOMS: Symptoms of exposure to this compound include skin rashes, eosinophilia, blood dyscrasias, stomatitis, anaphylactic shock, pruritus, scaling, and fever. (NTP, 1992)
Reactive GroupAlcohols and Polyols
Reactivity ProfileSTREPTOMYCIN SULFATE (2:3) (SALT) is a medicinal amino saccharide.
Air and Water ReactionsHygroscopic. Water soluble.
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.
Substances that inhibit the growth or reproduction of BACTERIA.
용도 및 제조
Household ProductsInformation on 1 consumer products that contain Streptomycin sulfate in the following categories is provided:
General Manufacturing InformationD-Streptamine, O-2-deoxy-2-(methylamino)-.alpha.-L-glucopyranosyl-(1.fwdarw.2)-O-5-deoxy-3-C-formyl-.alpha.-L-lyxofuranosyl-(1.fwdarw.4)-N1,N3-bis(aminoiminomethyl)-, sulfate (2:3): ACTIVE
응용 분야
개요Streptomycin was found in the culture broth of Streptomyces griseus by S. A. Waksman of Rutgers University in 1944; it was the second antibiotic introduced clinically (after penicillin). This drug is a water soluble, basic substance having an aminoglycoside structure and showing strong activity against a wide range of gram-positive and gram-negative bacteria including Mycobacterium. Streptomycin is the first choice among antituberculotic antibiotics and has been used for the therapy of Spirochaeta and Treponema infections.
용도Streptomycin sulfate is a sulfate salt of streptomycin that is a protein synthesis inhibitor. Streptomycin is an antibiotic drug, the first of a class of drugs called aminoglycosides to be discovered, and was the first antibiotic remedy for tuberculosis.
일반 설명An antibacterial. White to light gray or pale buff powder with faint amine-like odor.
상·하류 제품 정보
관련 반응
0건
현재 필터 조건에 해당하는 반응 기록이 없습니다.
화합물 노트
불러오는 중…