기본 정보
- CAS
29621-88-3- 표준 SMILES
N[C@@H](C[Se][Se]C[C@H](N)C(=O)O)C(=O)O- InChIKey
JULROCUWKLNBSN-IMJSIDKUSA-N- 분자식
- C6H12N2O4Se2
- 평균 분자량
- 334.11 g/mol
- 단동위원소 질량
- 335.91274946
개요
RN given refers to parent cpd; structure
이름 및 식별자
- 우선 이름
- Selenocystine
- IUPAC
- (2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]diselanyl]propanoic acid
- 영어명
- L-SELENOCYSTINE
- 분자식
- C6H12N2O4Se2
- 분자량
- 334.09
이름 및 동의어
1464-43-3CHEBI:28553RefChem:8848323,3'-diselane-1,2-diylbis(2-aminopropanoic acid)3,3'-Diselenobisalanine3,3'-DiselenodialanineSelenocystineL-Selenocystine29621-88-3Seleno-L-cystineSelenocystine, L-C6H12N2O4Se2
이름 더 보기
H-Se-Cystine-OHL-SELENOCYSTINE 98%L-Selenocystine,98%Seleno-L-cystine 95%3’-diselenodi-l-alanin3,3'-DISELENO-L-ALANINEl-3,3’-diselenodialanine
L-3,3'-DiselenodialanineAlanine, 3,3'-diselenodi-, L-(2R,2'R)-3,3'-diselanediylbis(2-aminopropanoic acid)MFCD00800971261B157KR83,3'-Diselenobis[L-alanine]L-Selenocystine Preparation Kit(2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]diselanyl]propanoic acid
데이터베이스 식별자
- CAS
29621-88-3- PubChem CID
- 207306
- DTXSID
DTXSID001044310- ChEMBL
CHEMBL5283716- UNII
- 261B157KR8、493154PTZ7
- EC Number
- 608-382-6
- Nikkaji
물성
구조 계산 물성
- 극성 표면적
- 127 Ų
- 수소 결합 공여자 수
- 4
- 수소 결합 수용자 수
- 6
- 회전 가능 결합 수
- 7
- 무거운 원자 수
- 14
- 형식 전하
- 0
- 복잡도
- 192
물리화학적 성질
- 녹는점
- 224.5 · 224.5-229.5 °C (lit.)
- 끓는 점
- 538.3 · 538.3±60.0 °C(Predicted)
- 저장 조건
- 2 · 2-8°C
- 용해도
- 산수용성(약간 용해됨), 염기성수용성(약간 용해됨)
- 산도 계수 (pKa)
- 1.69 · 1.69±0.10(Predicted)
- 물리적 상태
- 가루
- 색상
- 노란색
- BRN
- 1969559 · 1969559
- 안정성
- 흡습성
- 주요 응용
- 펩타이드 합성
- InChI
- 1S/C6H12N2O4Se2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1
- InChIKey
- JULROCUWKLNBSN-IMJSIDKUSA-N
- SMILES
- N[C@@H](C[Se][Se]C[C@H](N)C(O)=O)C(O)=O
화학적 성질
yellow fine powder
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
Danger
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
P260, P261, P264, P270, P271, P273, P301+P316, P304+P340, P316, P319, P321, P330, P391, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 41 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Hazard Classes and CategoriesAcute Tox. 3 (100%)
안전 데이터
- wgk
- 3
- rtecs
- AY6032000
- ridadr
- UN 3283 6.1/PG 3
- HS 번호
- 29319090
- risk_code
- 23/25-33-50/53
- hazard_code
- T,N
- safety_code
- 20/21-28-45-60-61
- 포장분류
- III
- 위험 등급
- 6.1
- Hazard Classifications
- Acute Tox. 3 InhalationAcute Tox. 3 OralAquatic Acute 1Aquatic Chronic 1STOT RE 2
- 스토리지 클래스
- 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
응용 분야
개요L-Selenocystine is a diselenide-bridged amino acid that may be confused with selenocysteine (Sec), which is a rare amino acid featuring a single selenium atom. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. This compound can be reduced by low molecular thiols and disulfide reductases to Sec. It is reduced to Sec by mammalian thioredoxin reductase (apparent Km = 6.0 μM), and this property can be used to assay thioredoxin reductase activity. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types.
용도Seleno-L-cystine can be used for the synthesis of:Biologically active selenol compounds.Non-natural selenylated diamino acids.
공급사100 곳
国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖南韵邦生物科技股份有限公司0731-88532326 13319508186 · [email protected]
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