Tesaglitazar

HCID 208901
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기본 정보

CAS
251565-85-2
표준 SMILES
CCO[C@@H](Cc1ccc(OCCc2ccc(OS(C)(=O)=O)cc2)cc1)C(=O)O
InChIKey
CXGTZJYQWSUFET-IBGZPJMESA-N
분자식
C20H24O7S
평균 분자량
408.5 g/mol
단동위원소 질량
408.12427427

이름 및 식별자

우선 이름
Tesaglitazar
IUPAC
(2S)-2-ethoxy-3-[4-[2-(4-methylsulfonyloxyphenyl)ethoxy]phenyl]propanoic acid
영어명
(S)-2-Ethoxy-3-[4-[2-(4-methanesulfonyloxy-phenyl)-ethoxy]-phenyl]-propionic acid
분자식
C20H24O7S
분자량
408.47

이름 및 동의어

Tesaglitazar251565-85-2GalidaAZ-242AR-H039242XXBR-44608(s)-2-ethoxy-3-(4-(2-(4-methylsulphonyloxyphenyl)ethoxy)phenyl)propanoic acidAR-H-0392426734037O3L(2S)-2-Ethoxy-3-(4-(2-(4-((methylsulfonyl)oxy)phenyl)ethoxy)phenyl)propanoic acid(2S)-2-ETHOXY-3-[4-(2-{4-[(METHYLSULFONYL)OXY]PHENYL}ETHOXY)PHENYL]PROPANOIC ACID(S)-2-ethoxy-3-(4-((4-(methylsulfonyloxy)phenethyl)oxy)phenyl)propanoic acid
이름 더 보기
GalidAZ 242AR-H 039242TesaglitizarAR-H 039242XXTesaglitazar, 10 mM in DMSO2-ethoxy-3-[4-[2-(4-methylsulfonyloxyphenyl)ethoxy]phenyl]propanoic acid
2-ethoxy-3-(4-((4-(methylsulfonyloxy)phenethyl)oxy)phenyl)propanoic acidDTXSID4048773tesaglitazarum(2S)-2-Ethoxy-3-[4-[2-[4-[(methylsulfonyl)oxy]phenyl]ethoxy]phenyl]propanoic acidRefChem:896625DTXCID401508653675-830-5(S)-2-Ethoxy-3-(4-(4-((methylsulfonyl)oxy)phenethoxy)phenyl)propanoic acid

데이터베이스 식별자

CAS
251565-85-2
PubChem CID
208901
DTXSID
DTXSID4048773
ChEMBL
CHEMBL282686
UNII
6734037O3L
EC Number
675-830-5
Nikkaji
J1.856.738E

물성

구조 계산 물성

XLogP
3.5
극성 표면적
108 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
7
회전 가능 결합 수
11
무거운 원자 수
28

물리화학적 성질

녹는점
83 · 83-85°C
끓는 점
611 ℃ · 611℃
밀도
1.278 · 1.278
인화점
324 ℃ · 324℃
저장 조건
2 · 2-8°C
용해도
클로로포름(약간 용해됨), 메탄올(약간 용해됨)

화학적 성질

White Solid

안전 및 규제

GHS 분류

GHS Classification · 5건

Warning

H302 (33.3%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (66.7%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (66.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (33.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 3 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Hazard Classes and CategoriesAcute Tox. 4 (33.3%)；Skin Irrit. 2 (66.7%)；Eye Irrit. 2 (66.7%)；STOT SE 3 (33.3%)

안전 데이터

wgk
WGK 3
Hazard Classifications
Acute Tox. 4 Oral
스토리지 클래스
11 - Combustible Solids

화학 및 산업

약리 정보

PharmacodynamicsTreatment with tesaglitazar lowered fasting plasma glucose, improved glucose tolerance, substantially reduced fasting and postload insulin levels, and markedly lowered fasting TG and improved lipid tolerance.

응용 분야

용도Dual -acting peroxisome proliferator-activated receptor (PPAR) a and agonist. Antidiabetic

상·하류 제품 정보

공급사51 곳

陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
上海仲因实业有限公司2537653158 16621191650 · [email protected]

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