피마게딘

Aminoguanidine

HCID 2146CAS 79-17-4
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기본 정보

표준 SMILES
NN=C(N)N
InChIKey
HAMNKKUPIHEESI-UHFFFAOYSA-N
분자식
CH6N4
평균 분자량
74.09 g/mol
단동위원소 질량
74.05924619

개요

Aminoguanidine is a one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor and an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is a member of guanidines and a one-carbon compound.

이름 및 식별자

우선 이름
Aminoguanidine
IUPAC
2-aminoguanidine
현지명
피마게딘
영어명
Aminoguanidine
분자식
CH6N4
분자량
74.09

이름 및 동의어

aminoguanidinePimagedineHydrazinecarboximidamide79-17-4Guanyl hydrazineMonoaminoguanidineAminate baseImino semicarbazide1-aminoguanidinepimagedinaSCQ4EZQ113DTXSID5040964
이름 더 보기
피마게딘Aids030897Aids-030897N-AminoguanidineAminoguanidine (ag)Ribavirin Impurity S
CHEBI:40618pimagedinumRefChem:112042DTXCID3020964201-183-12-aminoguanidinePimagedine [INN]GUANIDINE, AMINO-

데이터베이스 식별자

CAS
79-17-4
PubChem CID
2146
DTXSID
DTXSID5040964
ChEMBL
CHEMBL225304
ChEBI
CHEBI:40618
UNII
SCQ4EZQ113
EC Number
201-183-1
Nikkaji
J5.508E

물성

구조 계산 물성

XLogP
-1.5
극성 표면적
90.4 Ų
수소 결합 공여자 수
3
수소 결합 수용자 수
2
회전 가능 결합 수
0
무거운 원자 수
5

실험 및 물리화학적 성질

DrugsPharmaceuticals -> Listed in ZINC15

물리화학적 성질

녹는점
182 · 182-185 °C (decomp)
끓는 점
159.5 · 159.5±23.0 °C(Predicted)
밀도
1.72 · 1.72±0.1 g/cm3(Predicted)
굴절률
1.666 · 1.6660 (estimate)
산도 계수 (pKa)
11.08 · 11.08±0.70(Predicted)

화학 및 산업

약리 정보

Mechanism of ActionPimagedine reportedly inhibits the formation of glycosylated proteins (advanced glycosylation end-products) and has other actions including inhibition of aldose reductase.
MeSH Pharmacological ClassificationCompounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

응용 분야

용도Inhibitor (advanced glycosylation end-product formation).

상·하류 제품 정보

공급사22 곳

Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
武汉丰泰威远科技有限公司+86-27-8746-5837 +86-18627785180 · [email protected]
武汉丰泰威远科技有限公司027-87465837 19945049750 · [email protected]
上海遐瑞医药科技有限公司+86 21 61551611
추가 설명 · 1건

정의ChEBI: Aminoguanidine is a one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor and an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is a member of guanidines and a one-carbon compound.

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