기본 정보
- CAS
1425-61-2- 표준 SMILES
CN[C@@H]1[C@H](O[C@H]2[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](N=C(N)N)[C@@H](O)[C@@H]3N=C(N)N)O[C@@H](C)[C@]2(O)CO)O[C@@H](CO)[C@H](O)[C@H]1O.CN[C@@H]1[C@H](O[C@H]2[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](N=C(N)N)[C@@H](O)[C@@H]3N=C(N)N)O[C@@H](C)[C@]2(O)CO)O[C@@H](CO)[C@H](O)[C@H]1O.O=S(=O)(O)O.O=S(=O)(O)O.O=S(=O)(O)O- InChIKey
CZWJCQXZZJHHRH-YCRXJPFRSA-N- 분자식
- C42H88N14O36S3
- 평균 분자량
- 1,461.4 g/mol
개요
Dihydrostreptomycin Sulfate is a semi-synthetic aminoglycoside antibiotic with bactericidal properties. Dihydrostreptomycin sulfate inhibits protein synthesis by binding to the 30S ribosomal subunit. This antibiotic is active against most gram-positive and gram-negative organisms and is used in the treatment of tuberculosis and tulemia.
이름 및 식별자
- 우선 이름
- Dihydrostreptomycin Sulfate
- IUPAC
- bis(2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-hydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine);sulfuric acid
- 영어명
- Dihydrostreptomycin sesquisulfate salt
- 분자식
- C21H43N7O16S
- 분자량
- 681.67
이름 및 동의어
Dihydrostreptomycin sulfate5490-27-7DIHYDROSTREPTOMYCIN SESQUISULFATEDihydrostreptomycin sulfate (USP)Dihydrostreptomycin sequisulphateDTXSID6045824NSC-7567392-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-hydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine;sulfuric acidT7D4876IUEDTXCID4025824D-Streptamine, O-2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-(hydroxymethyl)-alpha-L-lyxofuranosyl-(1-4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt)Pfizer-Strep
이름 더 보기
DIDROMYCINE SULFATEWelcome to consult Zhang JunTDIHYDROSTREPTOMYCIN SESQUISULFATE SALDihydrostreptomycin sesquisulfate saltDIHYDROSTREPTOMYCIN SESQUISULFATE SALT USP/EP/BP4-O-[2-O-[2-(Methylamino)-2-deoxy-α-L-glucopyranosyl]-5-deoxy-3-(hydroxymethyl)-α-L-lyxofuranosyl]-N,N'-diamidino-D-streptamine/sulfuric acid,(1:x)
물성
구조 계산 물성
- 극성 표면적
- 928 Ų
- 수소 결합 공여자 수
- 32
- 수소 결합 수용자 수
- 42
- 회전 가능 결합 수
- 18
- 무거운 원자 수
- 95
- 형식 전하
- 0
- 복잡도
- 993
실험 및 물리화학적 성질
Animal DrugsActive Ingredients (Dihydrostreptomycin Sulfate) -> FDA Greenbook
물리화학적 성질
- 녹는점
- 200 °C · >200°C (dec.)
- 저장 조건
- 2 · 2-8°C
- 용해도
- 2 O: · H2O: 50 mg/mL, 투명, 희미한 노란색
- 물리적 상태
- 수정 같은
- 색상
- 하얀색
- 안정성
- 흡습성
- InChIKey
- GSPKOIJAMLDYCY-XKIHQDMANA-N
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 21.3% (38 of 178) of reports.
Danger
H302 (54.5%): Harmful if swallowed [Warning Acute toxicity, oral]
P203, P260, P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P318, P319, P321, P330, P362+P364, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 178 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Regulatory Information
Dihydrostreptomycin sulphate: Does not have an individual approval but may be used under an appropriate group standard
Dihydrostreptomycin sulfate: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Other Safety Information
IMAP assessments - D-Streptamine, O-2-deoxy-2-(methylamino)-.alpha.-L-glucopyranosyl-(1.fwdarw.2)-O-5-deoxy-3-C-(hydroxymethyl)-.alpha.-L-lyxofuranosyl-(1.fwdarw.4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt): Environment tier I assessment
Hazard Classes and CategoriesAcute Tox. 4 (54.5%)
안전 데이터
- wgk
- 3
- rtecs
- WK2236000
화학 및 산업
약리 정보
MeSH Pharmacological ClassificationSubstances that inhibit the growth or reproduction of BACTERIA.
용도 및 제조
Use ClassificationAnimal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
General Manufacturing InformationD-Streptamine, O-2-deoxy-2-(methylamino)-.alpha.-L-glucopyranosyl-(1.fwdarw.2)-O-5-deoxy-3-C-(hydroxymethyl)-.alpha.-L-lyxofuranosyl-(1.fwdarw.4)-N1,N3-bis(aminoiminomethyl)-, sulfate (2:3): INACTIVE
공급사33 곳
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
陕西缔都化学有限公司029-029-81123119 17391733320 · [email protected]
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
Hebei Yanxi Chemical Co., Ltd.+86-17531190177 · [email protected]
湖北恒硕化工有限公司027-82830253 13995541600 · [email protected]
Protheragen-ING+86-15618352007 · [email protected]
淄博容纳生物科技有限公司+86-86-13583358881 +8618560316533 · [email protected]
上海梅凯科技有限公司021-68689288 15300790979 · [email protected]
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