Fumagillol

HCID 222778

기본 정보

CAS: 108102-51-8
표준 SMILES: CO[C@@H]1[C@H](O)CC[C@]2(CO2)[C@H]1[C@@]1(C)O[C@@H]1CC=C(C)C
InChIKey: CEVCTNCUIVEQOY-JQOWZUPLSA-N
분자식: C16H26O4
평균 분자량: 282.37 g/mol

개요

Fumagillol is a sesquiterpenoid with antimicrobial properties. It has a role as an antimicrobial agent. It is a spiro-epoxide, a sesquiterpenoid and a secondary alcohol.

이름 및 식별자

우선 이름: Fumagillol
IUPAC: (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-ol
영어명: fumagillol
분자식: C16H26O4
분자량: 282.38

이름 및 동의어

Fumagillol108102-51-8Gelcohol409OS4DE8W(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-olCHEBI:3249351-Oxaspiro(2.5)octan-6-ol, 5-methoxy-4-(2-methyl-3-(3-methyl-2-butenyl)oxiranyl)-, (3R-(3alpha,4alpha(2R*,3R*),5beta,6beta))-(3R,4S,5S,6R)-5-methoxy-4-((2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl)-1-oxaspiro(2.5)octan-6-olRefChem:141646(-)-FumagillolSCHEMBL2553407NSC9665

이름 더 보기

Fumagillol, 10 mM in DMSOFumagillol,Bacterial,inhibit,Inhibitor1-Oxaspiro[2.5]octan-6-ol, 5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-, (3R,4S,5S,6R)-

Alcohol-I from Fumagillin(3R,4S,5S,6R)-5-methoxy-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-olFOS 37; Gelcohol(3r,4s,5s,6r)-5-methoxy-4-[(2r,3r)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-ol1-OXASPIRO(2.5)OCTAN-6-OL, 5-METHOXY-4-((2R,3R)-2-METHYL-3-(3-METHYL-2-BUTEN-1-YL)-2-OXIRANYL)-, (3R,4S,5S,6R)-MLS003389373FOS-371-Oxaspiro[2.5]octan-6-ol,5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-,(3R,4S,5S,6R)-

물성

구조 계산 물성

XLogP: 1.7
극성 표면적: 54.5 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 4
회전 가능 결합 수: 4
무거운 원자 수: 20
형식 전하: 0
복잡도: 417

물리화학적 성질

녹는점: 54 · 54-56 °C(Solv: ligroine (8032-32-4))
끓는 점: 140 °C · 140 °C(Press: 0.02 Torr)
밀도: 1.13 · 1.13±0.1 g/cm3(Predicted)
저장 조건: -20 °C · Store at -20°C
용해도: 100 mg/mL · DMSO : 100 mg/mL (354.13 mM; Need ultrasonic)
물리적 상태: 고체
산도 계수 (pKa): 14.21 · 14.21±0.60(Predicted)
색상: 흰색에서 황백색까지

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

안전 데이터

신호 어: Danger
유해·위험 문구: 암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드 H228

화학 및 산업

응용 분야 · 1건

용도Fumagillol is an analog of Fumagillin (F862650), a compound isolated from the fungus Aspergillus fumigatus. Fumagillin is an antimicrobial agent used in the treatment of microsporidiosis. Fumagillin shows promise as both an an anti-infective and antiangiogenic agent.

공급사42 곳

陕西缔都新材料有限公司81124267 17392282731 · [email protected]

武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]

艾吉析科技（上海）有限公司17717235263 · [email protected]

咸宁深蓝生物医药研发有限公司18171815831 · [email protected]

上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]

화합물 노트

불러오는 중…

부분 구조 검색 유사 구조 찾기

기본 정보

CAS: 108102-51-8
표준 SMILES: CO[C@@H]1[C@H](O)CC[C@]2(CO2)[C@H]1[C@@]1(C)O[C@@H]1CC=C(C)C
InChIKey: CEVCTNCUIVEQOY-JQOWZUPLSA-N
분자식: C16H26O4
평균 분자량: 282.37 g/mol

개요

Fumagillol is a sesquiterpenoid with antimicrobial properties. It has a role as an antimicrobial agent. It is a spiro-epoxide, a sesquiterpenoid and a secondary alcohol.