108171-26-2CCC(Cl)C(Cl)C(Cl)CC(Cl)C(Cl)C(C)ClZPSFPNSXYWWGRF-UHFFFAOYSA-N2,3,4,6,7,8-hexachlorodecane is a short chain chlorinated paraffin (SCCP). Chlorinated paraffins are synthetic compounds used primarily as coolants and lubricants in metal forming and cutting, in addition to being used as plasticizers and flame retardants in rubber, paints, adhesives, sealants and plastics. SCCPs (C10РC13 chloroalkanes) were included in 2008 in the European Chemicals Agency (ECHA) list of Substances of Very High Concern (SVHC) due their being a PBT (persistent, bioaccumulative and toxic) and vPvB (very persistent and very bioaccumulative) class of compounds. Substances in the list of SVHCs are those for which ECHA is considering imposing a requirement for authorization for some or all uses. Acute toxicity of SCCPs (C10-13) is very low. SCCPs may cause skin and eye irritation upon repeated application, but do not appear to induce skin sensitization (L2053). Chlorinated paraffins (average chain length C12; approx. 60% chlorine by weight) are listed on the International Agency for Research on Cancer's (IARC) Carcinogen List as 'Possible Carcinogens.' On the U.S. National Toxicology Program (NTP) Carcinogen List they are listed as 'Reasonably Anticipated to Be a Carcinogen.' There are no data on fertility or developmental effects for humans. No changes in reproductive organs were observed in a 13 week study with rats and mice dosed with 5000 and 2000 mg/kg/day of an SCCP. In addition, developmental effects were observed in rats at 2000 mg/kg/day but not at lower doses (L2053). (L2054)
108171-26-2Chlorinated paraffins are chlorinated long-chain aliphatic compounds. They exist as light-yellow to amber-colored viscous, oily liquids that are usually odorless. The commercial products are complex mixtures that contain paraffins with various carbon-chain lengths and varying chlorine content. The commercial products normally contain stabilizers to inhibit decomposition and may contain isoparaffins (ow) ranges from 4.48 to 7.38 (IPCS 1996, HSDB 2009).
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
Chlorinated Paraffins: C12, 60% Chlorine
TR-308: Toxicology and Carcinogenesis Studies of Chlorinated Paraffins (C12, 60% Chlorine) (CASRN 108171-26-2) in F344/N Rats and B6C3F1 Mice (Gavage Studies) (1986 )
08/14/85
Clear Evidence
Clear Evidence
Clear Evidence
용도Chlorinated paraffins are used as extreme-pressure-lubricant additives in metalworking fluids; as flame retardants in plastics, rubber, and paints; to improve water resistance of paints and fabrics; and as a secondary plasticizer in polyvinyl chloride. Small amounts are also used in caulks, sealants, adhesives, detergents, inks, finished leather, and other miscellaneous products, and are allowed as an indirect food additive (NTP 1986, CMR 2002, HSDB 2009, FDA 2010). In the United States, about 50% of chlorinated paraffins are used in metalworking fluids, 20% in plastics additives, 12% in rubber, 9% in coatings, 6% in adhesives, caulks, and sealants, and the remaining 3% for miscellaneous purposes (CMR 2002). Chlorinated paraffins have replaced polychlorinated biphenyls as fire-retardant lubricants (NTP 1986). Between 1914 and 1918, large amounts of chlorinated paraffins were used as solvents for dichloramine-T in antiseptic nasal and throat sprays (IPCS 1996).
일반 설명Clear colorless to light amber viscous liquid. Slight odor or no odor.
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CHEMBL3184336