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HCID 2350생성일: 2026년 10월 27일

4-((4-Chlorophenyl)-2-pyridinylmethoxy)-1-piperidinebutanoic Acid

rac Bepotastine · Rac-Bepotastine-d6 · YWGDOWXRIALTES-UHFFFAOYSA-N · 4-[(4-Chlorophenyl)-2-pyridinylmethoxy]-1-piperidinebutanoic acid · 1-Piperidinebutanoic acid, 4-[(4-chlorophenyl)-2-pyridinylmethoxy]-

https://huagongshe.com/ko/chemical/2350

4-((4-Chlorophenyl)-2-pyridinylmethoxy)-1-piperidinebutanoic Acid 분자 구조식

식별자 및 물리적 특성

CAS No.	1070505-53-1
분자식	C21H25ClN2O3
평균 분자량	388.9 g/mol
단동위원소 질량	388.15537034 g/mol
SMILES	O=C(O)CCCN1CCC(OC(c2ccc(Cl)cc2)c2ccccn2)CC1
InChIKey	YWGDOWXRIALTES-UHFFFAOYSA-N
PubChem CID	2350
ChEMBL	CHEMBL4877190
DTXSID	DTXSID70869727

화학 및 물리적 성질

XLogP	1
극성 표면적	62.7
수소 결합 공여자 수	1
수소 결합 수용자 수	5
회전 가능 결합 수	8
무거운 원자 수	27
형식 전하	0
복잡도	449
용해도	5.03e-02 g/L
Physical Description	Solid
밀도	1.26

안전 및 규제

노출 경로	Oral, Ophthalmic. Tmax, after single dose, opthalmic = 1.2 hoursCmax, 1.5%, opthalmic dose = 7.3 &#1771.9 ng/mLAfter 24 hours post-installation, levels of bepotastine are below quantifiable limit of 2 ng/mL. Minimal systemic absorption with opthalmic dosage form.
독성 요약	Because of a type 1 hypersensitivity reaction cascade that is triggered by antigen exposure, allergic conjunctivitis occurs. Allergen exposure is followed by conjunctival mast cell degranulation and histamine released as a result of the formation of complementary IgE cross-links on the conjunctiva. Due to the release of histamine, symptoms such as itching can be observed. Bepotastine works to relieve itchy eyes by three primary mechanisms of action. It is a non-sedating, selective antagonist of the histamine 1 (H1) receptor, a mast cell stabilizer, and it suppresses the migration of eosinophils into inflamed tissues to prevent tissue damage and worsening of allergic inflammation of the conjunctiva.
Carcinogen Classification	No indication of carcinogenicity to humans (not listed by IARC).

4-((4-Chlorophenyl)-2-pyridinylmethoxy)-1-piperidinebutanoic Acid｜Huagongshe