Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
아스트로믹설페이트
아스트로믹설페이트 · A44747 · A 44747 · A-44747 · Abbott 44747 · Kw-1070 sulfate · Unii-poy3S0T3bd · ASTROMICINSULFATE
식별자 및 물리적 특성
| CAS No. | 72275-67-3 |
|---|---|
| 분자식 | C17H37N5O10S |
| 평균 분자량 | 503.57 g/mol |
| SMILES | CO[C@H]1[C@@H](O)[C@H](N)[C@@H](O[C@H]2O[C@H]([C@H](C)N)CC[C@H]2N)[C@H](O)[C@@H]1N(C)C(=O)CN.O=S(=O)(O)O |
| InChIKey | ISMJYDUGJHHFEG-QPABWCPOSA-N |
| PubChem CID | 23622607 |
| 현지명 | 아스트로믹설페이트 |
용도
개요
Astromicin sulfate is a pseudodisaccharide aminoglycoside antibiotic with a spectrum comparable to amikacin. It is active against many gentamicin and amikacin resistant bacteria expressing aminoglycoside-modifying enzymes, with the exception of aminoglycoside 3-acetyltransferase.
일반 설명
Astromicin was found in the culture broth of Micromonospora olivoasterospora by Nara et al. of Kyowa Hakko Kogyo Co. in 1976. It has a unique conformation with an acylated diamino inositol moiety different from other aminoglycoside antibiotics. Astromicin is produced with one major byproduct, fortimicin B, and several minor components.