기본 정보
- CAS
920113-03-7- 표준 SMILES
CN1CC[C@@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@@H]1CO.Cl- InChIKey
OOVTUOCTLAERQD-OJMBIDBESA-N- 분자식
- C21H21Cl2NO5
- 평균 분자량
- 438.3 g/mol
- 단동위원소 질량
- 437.0796782
이름 및 식별자
- 우선 이름
- P 276-00
- IUPAC
- 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl]chromen-4-one;hydrochloride
- 영어명
- P276
- 분자식
- C21H21Cl2NO5
- 분자량
- 438.3
이름 및 동의어
920113-03-7Riviciclib hydrochlorideP276-00DRP53ZDY6HP-27600P 276-00P-276-004H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-((2R,3S)-2-(hydroxymethyl)-1-methyl-3-pyrrolidinyl)-, hydrochloride (1:1)RefChem:928418P2762-(2-Chlorophenyl)-5,7-dihydroxy-8-((2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl)-4H-chromen-4-one hydrochlorideRiviciclib HCl
이름 더 보기
CS-996P276 USP/EP/BPRiviciclib HCl (P276-00)RIVICICLIB HYDROCHLORIDE (P276-00)Riviciclib hydrochloride, 10 mM in DMSOinhibit,Inhibitor,Riviciclib,CDK,Riviciclib hydrochloride,Cyclin dependent kinase,Apoptosis2-(2-Chlorophenyl)-5,7-dihydroxy-8-((2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl)-4H-chromen-4-one HCl
2-(2-chlorophenyl)-5,7-dihydroxy-8-[(2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl]chromen-4-one;hydrochlorideUNII-DRP53ZDY6H2-(2-chlorophenyl)-5,7-dihydroxy-8-[(2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl]-4H-chromen-4-one hydrochloride920113-03-7 (HCl)SCHEMBL663220orb1685539CHEMBL3991935SCHEMBL29387962
데이터베이스 식별자
- CAS
920113-03-7- PubChem CID
- 23643975
- DTXSID
DTXSID201366259- ChEMBL
CHEMBL2312181、CHEMBL3991935- UNII
- DRP53ZDY6H
물성
구조 계산 물성
- 극성 표면적
- 90.2 Ų
- 수소 결합 공여자 수
- 4
- 수소 결합 수용자 수
- 6
- 회전 가능 결합 수
- 3
- 무거운 원자 수
- 29
- 형식 전하
- 0
- 복잡도
- 628
물리화학적 성질
- 저장 조건
- -20 ° · Store at -20° C
- 용해도
- DMSO에 용해됨
- 물리적 상태
- Solid
- 색상
- Off-white to light yellow
화학 및 산업
응용 분야
용도P276-00 is a cyclin-dependent kinase (CDK) inhibitor. P276-00 has shown to be highly selective for cancer cells and has shown to produce potent inhibition of Cdk4-D1 activity. P276-00 also induces apoptosis in human promyelocytic leukemia (HL-60) cells.
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공급사54 곳
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Career Henan Chemica Co
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