CAS 69-52-3 Ampicillin Sodium (HCID 23663979)

개요

Ampicillin sodium is an organic sodium salt. It contains an ampicillin(1-).

이름 및 식별자

우선 이름: Ampicillin Sodium
IUPAC: sodium (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
현지명: 암피실린 나트륨
영어명: Ampicillin sodium
분자식: C16H20N3NaO4S
분자량: 373.4

이름 및 동의어

AMPICILLIN SODIUM69-52-3Ampicillin sodium saltSodium ampicillinOmnipen-NAmpicillin natriumTotacillin-NPenbritin-SAmpicillin (as sodium)Sodium D-(-)-alpha-aminobenzylpenicillinJFN36L5S8KAmpicillinum natricum

이름 더 보기

암피실린나트륨암피실린나트륨XLD AGARpenialmenpena/nAlpen-nAnhypenAmcill-sCitteral

D(-)-alpha-Aminobenzylpenicillin sodium saltAmpicillin sodium, sterileNSC-755864CHEBI:34535DTXSID60988759Monosodium D-(-)-6-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylateAmp EquineAmp-Equine

데이터베이스 식별자

CAS: 69-52-3
PubChem CID: 23663979
DTXSID: DTXSID60988759
ChEMBL: CHEMBL1200758
ChEBI: CHEBI:34535
UNII: JFN36L5S8K
EC Number: 200-708-1

물성

구조 계산 물성

극성 표면적: 141 Å²
수소 결합 공여자 수: 2
수소 결합 수용자 수: 6
회전 가능 결합 수: 4
무거운 원자 수: 25
형식 전하: 0
복잡도: 568

실험 및 물리화학적 성질

Human Drugs · 2건

FDA approved drugs -> Active ingredient

Animal DrugsActive Ingredients (Ampicillin Sodium) -> FDA Greenbook

Collision Cross Section179.1 Å² [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

물리화학적 성질

녹는점: 215 °C · 215 °C (dec.)(lit.)
저장 조건: 2 · 2-8°C
용해도: 2 O: · H2O: 50 mg/mL, 투명, 매우 희미한 노란색
물리적 상태: 가루
색상: 약간의 노란색을 띤 흰색
수소이온지수(pH): pH(100g/l, 25℃):8.0～10.0
생물학적 소스: synthetic (chemical)
수용성: 물에 자유롭게 용해됩니다. 아세톤에 난용성
BRN: 4119211 · 4119211
InChIKey: XCZQUQSOMVIRFX-AGYZSTNLNA-N
SMILES: C([C@H]1C(S[C@]2([H])[C@H](NC(=O)[C@@H](C3C=CC=CC=3)N)C(=O)N12)(C)C)(=O)O.[NaH] |&1:1,4,6,10,r|

화학적 성질

White or almost white powder, hygroscopic.

안전 및 규제

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 0.3% (1 of 331) of reports.

Danger

H317 (99.1%): May cause an allergic skin reaction [Warning Sensitization, Skin]

P233, P260, P261, P271, P272, P280, P284, P302+P352, P304+P340, P321, P333+P317, P342+P316, P362+P364, P403, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 331 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory InformationSodium ampicillin: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-, monosodium salt,[2S-[2.alpha.,5.alpha.,6.beta.(S*)]]-: Human health tier I assessment

Hazard Classes and CategoriesSkin Sens. 1A (99.1%)

독성 정보

Drug Induced Liver Injury · 6건

Drug Induced Liver Injury Rank (DILIrank 2.0)

Ampicillin sodium

vLess-DILI-concern

3

Warnings & precautions

DOI:10.1016/j.drudis.2016.02.015

안전 데이터

wgk: 2
rtecs: XH8400000
독성: LD50 oral in rat: > 5314mg/kg
HS 번호: 29419000
risk_code: 42/43-36/37/38-22
hazard_code: Xi,Xn
safety_code: 22-36/37-45-36-26
기존화학 물질: KE-01540
F 고인화성물질: 3-10
자연 발화 온도: 301 °C
Hazard Classifications: Resp. Sens. 1Skin Sens. 1
스토리지 클래스: 10 - Combustible liquids

화학 및 산업

약리 정보

FDA Pharmacological Classification · 4건

AMPICILLIN INJECTION

Penicillins [CS]; Penicillin-class Antibacterial [EPC]

AMPICILLIN SODIUM

Penicillin-class Antibacterial [EPC]; Penicillins [CS]

MeSH Pharmacological ClassificationSubstances that inhibit the growth or reproduction of BACTERIA.

용도 및 제조

Use ClassificationAnimal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients

응용 분야 · 2건

용도Ampicillin sodium salt is a reagent for transformed cells expressing beta-lactamase. It acts as a structural analogue of acyl-D-alanyl-D-alanine, acylates the transpeptidase enzyme and prevents the cross-linking of the peptidoglycan of the cell wall necessary for the growth of the bacterium.

일반 설명Chemical structure: -lactam

상·하류 제품 정보

상류 원료

공급사100 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

北京华美互利生物化工010-56205725 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

上海如吉生物科技发展有限公司+86-21-65211385-8001 36031160 · [email protected]

LGM Pharma1-(800)-881-8210 · [email protected]

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암피실린 나트륨

기본 정보

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