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HCID 23749생성일: 2026년 11월 1일

p-아조벤젠아르소네이트

p-아조벤젠아르소네이트 · p-Azobenzenearsonate · 4,4'-azodibenzenearsonic acid · Arsonic acid, As,As'-(1,2-diazenediyldi-4,1-phenylene)bis-

https://huagongshe.com/ko/chemical/23749

식별자 및 물리적 특성

CAS No.	7334-23-8
분자식	C12H12As2N2O6
평균 분자량	430.08 g/mol
단동위원소 질량	429.91273 g/mol
SMILES	O=[As](O)(O)c1ccc(N=Nc2ccc([As](=O)(O)O)cc2)cc1
InChIKey	ITRMROGJSNWFKO-UHFFFAOYSA-N
PubChem CID	23749
ChEMBL	CHEMBL1449046
ChEBI	CHEBI:53554
DTXSID	DTXSID501028210
현지명	p-아조벤젠아르소네이트

화학 및 물리적 성질

극성 표면적	140
수소 결합 공여자 수	4
수소 결합 수용자 수	8
회전 가능 결합 수	4
무거운 원자 수	22
형식 전하	0
복잡도	442
끓는 점	813.3±75.0 °C(Predicted)
pKa(산도 계수)	2.95±0.10(Predicted)

안전 및 규제

Minimum Risk Level	Acute Oral: 0.005 mg/kg/day (L134) Chronic Oral: 0.0003 mg/kg/day (L134) Chronic Inhalation: 0.01 mg/m3 (L134)
Treatment	Arsenic poisoning can be treated by chelation therapy, using chelating agents such as dimercaprol, EDTA or DMSA. Charcoal tablets may also be used for less severe cases. In addition, maintaining a diet high in sulfur helps eliminate arsenic from the body. (L20)
건강 영향	Arsenic poisoning can lead to death from multi-system organ failure, probably from necrotic cell death, not apoptosis. Arsenic is also a known carcinogen, esepcially in skin, liver, bladder and lung cancers. (T1, L20)
노출 경로	Oral (L2)inhalation (L2)dermal (L2)
독성 요약	Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by competing with phosphate it uncouples oxidative phosphorylation, thus inhibiting energy-linked reduction of NAD+, mitochondrial respiration, and ATP synthesis. Hydrogen peroxide production is also increased, which might form reactive oxygen species and oxidative stress. Arsenic's carginogenicity is influenced by the arsenical binding of tubulin, which results in aneuploidy, polyploidy and mitotic arrests. The binding of other arsenic protein targets may also cause altered DNA repair enzyme activity, altered DNA methylation patterns and cell proliferation. (T1, A17)
Signs and Symptoms	Exposure to lower levels of arsenic can cause nausea and vomiting, decreased production of red and white blood cells, abnormal heart rhythm, damage to blood vessels, and a sensation of
Carcinogen Classification	3, not classifiable as to its carcinogenicity to humans. (L135)

식별자 및 물리적 특성

CAS No.

7334-23-8

분자식

C12H12As2N2O6

평균 분자량

430.08 g/mol

단동위원소 질량

429.91273 g/mol

SMILES

O=[As](O)(O)c1ccc(N=Nc2ccc([As](=O)(O)O)cc2)cc1

InChIKey

ITRMROGJSNWFKO-UHFFFAOYSA-N

PubChem CID

23749

ChEMBL

CHEMBL1449046

ChEBI

CHEBI:53554

DTXSID

DTXSID501028210

현지명

p-아조벤젠아르소네이트

극성 표면적

140

수소 결합 공여자 수

수소 결합 수용자 수

회전 가능 결합 수

무거운 원자 수

형식 전하

복잡도

442

끓는 점

813.3±75.0 °C(Predicted)

pKa(산도 계수)

2.95±0.10(Predicted)

안전 및 규제

Minimum Risk Level

Acute Oral: 0.005 mg/kg/day (L134) Chronic Oral: 0.0003 mg/kg/day (L134) Chronic Inhalation: 0.01 mg/m3 (L134)

Treatment

Arsenic poisoning can be treated by chelation therapy, using chelating agents such as dimercaprol, EDTA or DMSA. Charcoal tablets may also be used for less severe cases. In addition, maintaining a diet high in sulfur helps eliminate arsenic from the body. (L20)

건강 영향

Arsenic poisoning can lead to death from multi-system organ failure, probably from necrotic cell death, not apoptosis. Arsenic is also a known carcinogen, esepcially in skin, liver, bladder and lung cancers. (T1, L20)

노출 경로

Oral (L2)inhalation (L2)dermal (L2)

독성 요약

Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by competing with phosphate it uncouples oxidative phosphorylation, thus inhibiting energy-linked reduction of NAD+, mitochondrial respiration, and ATP synthesis. Hydrogen peroxide production is also increased, which might form reactive oxygen species and oxidative stress. Arsenic's carginogenicity is influenced by the arsenical binding of tubulin, which results in aneuploidy, polyploidy and mitotic arrests. The binding of other arsenic protein targets may also cause altered DNA repair enzyme activity, altered DNA methylation patterns and cell proliferation. (T1, A17)

Signs and Symptoms

Exposure to lower levels of arsenic can cause nausea and vomiting, decreased production of red and white blood cells, abnormal heart rhythm, damage to blood vessels, and a sensation of

Carcinogen Classification

3, not classifiable as to its carcinogenicity to humans. (L135)