Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
삼염화 인
삼염화인 · 포스포러스트리클로라이드 · 삼염화 인 · 염화인 · 염화인(III) · 트라이클로로포스핀 · PCl3 · Phosphorous trichloride
식별자 및 물리적 특성
| CAS No. | 7719-12-2 |
|---|---|
| 분자식 | Cl3P |
| 평균 분자량 | 137.33 g/mol |
| 단동위원소 질량 | 135.88032 g/mol |
| SMILES | ClP(Cl)Cl |
| InChIKey | FAIAAWCVCHQXDN-UHFFFAOYSA-N |
| PubChem CID | 24387 |
| ChEBI | CHEBI:30334 |
| EC No. | 231-749-3 |
| DTXSID | DTXSID5029687 |
| 현지명 | 삼염화 인 |
화학 및 물리적 성질
| XLogP | 2.3 |
|---|---|
| 극성 표면적 | 0 |
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 0 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 4 |
| 형식 전하 | 0 |
| 복잡도 | 8 |
| 냄새 | PungentSmells like hydrochloric acid자극적이고 자극적인 냄새 |
| 밀도 | 1.574 at 69.8 °F (EPA, 1998) - Denser than waterwill sink1.574 at 21 °CRelative density (water = 1): 1.61.581.574 @25 °C1.574 g/mL at 25 °C |
| Viscosity | 0.65 cP at 0 °C0.438 cP at 50 °C |
| Color/Form | Clear colorless, fuming liquidColorless to yellow, fuming liquid. |
| 용해도 | Reacts with water (NIOSH, 2024)Reacts with water, ethanolsoluble in benzene, chloroform, etherSoluble in carbon tetrachlorideSolubility in water: reaction벤젠, 황화탄소, 에테르, 에 용해됨클로로포름, 사염화탄소에 용해됩니다. |
| Corrosivity | Corrodes most common construction materials. |
| 끓는 점 | 169 °F at 760 mmHg (EPA, 1998)76.1 °C76 °C76 °C @760 [mm Hg]74-78 °C(lit.) |
| Decomposition | When heated to decomposition it emits toxic fumes of /hydrogen chloride and phosphorus oxide/.DECOMPOSED BY WATER OR ALC.... If involved in a fire decomposes to produce hydrogen chloride, phosphoric acid, phosphine. |
| 녹는점 | -170 °F (EPA, 1998)-93.6 °C-112 °C-93 °C |
| 증기 밀도 | 4.75 (EPA, 1998) - Heavier than airwill sink (Relative to Air)4.75 (air= 1)Relative vapor density (air = 1): 4.754.75 (vs air) |
| 후각 역치 | Phosphorus trichloride ... can be detected at about 0.5 mg/cu m. |
| 증기압 | 100 mmHg at 69.8 °F (EPA, 1998)120.0 [mmHg]120 mm Hg at 25 °CVapor pressure, kPa at 21 °C: 13.3100 mmHg at 69.8 °F120 [mm Hg] @25 °C23.32 psi ( 55 °C) |
| 굴절률 | n20/D 1.5148(lit.) |
| 인화점 | 76°C |
| 저장 조건 | Store at RT. |
| 물리적 상태 | 액체 |
| 색상 | 노란색 |
| 비중 | approximate 1.6 |
| pH | 1 (20°C, 5g/L in H2O) |
| 용해도 | 물과 반응 |
| 비열 | Cp(gas): 0.52 J/(g·K), at 25℃ |
| Merck | 14,7358 |
| BRN | 969177 |
| 유전율 | 3.7(18℃) |
| 안정성 | 안정적이지만 빛에 민감합니다. 물, 많은 금속, 불소, 산, 산, 알코올 및 환원제를 포함한 다양한 유기 물질과 호환되지 않습니다. 물과의 반응은 격렬하며 독성 가스를 생성합니다. |
| InChI | 1S/Cl3P/c1-4(2)3 |
| InChIKey | FAIAAWCVCHQXDN-UHFFFAOYSA-N |
| SMILES | P(Cl)(Cl)Cl |
| NIST | Phosphorus trichloride(7719-12-2) |
| EPA | Phosphorus trichloride (7719-12-2) |
화학적 성질
Phosphorus trichloride is a colorless to yellow, fuming liquid. Odor like hydrochloric acid.
안전 및 규제
| GHS 분류 | DangerH300: Fatal if swallowed [Danger Acute toxicity, oral]H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]H330: Fatal if inhaled [Danger Acute toxicity, inhalation]H373 **: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]P260, P264, P270, P271, P280, P284, P301+P316, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P319, P320, P321, P330, P363, P403+P233, P405, and P501 (click each P-code to see the statement)This chemical does not meet GHS hazard criteria for 3.5% (12 of 345) of reports. |
|---|---|
| Hazards Identification | Water-reactive material (WR)Toxic/poison by inhalation (TIH/PIH) |
| 규제 정보 | Chemical: Phosphorus trichlorideStatus: Active Update: 30-08-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/14467Phosphorus trichloride: HSNO Approval: HSR003065 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| 기타 안전 정보 | IMAP assessments - Phosphorus trichloride: Human health tier I assessmentIMAP assessments - Phosphorus trichloride: Environment tier I assessment |
| 운송 라벨(DOT) | Poison Inhalation Hazard Corrosive |
| 화재 위험 | This material will react violently with water, producing heat and toxic and corrosive fumes. When heated to decomposition, it emits highly toxic fumes of chlorides and phosphorus oxides. It may ignite other combustible materials. Reacts violently with water. Reacts explosively with acetic acid, aluminum, chromyl chloride, diallylphosphite and allyl alcohol, dimethyl sulfoxide, fluorine, hydroxylamine, iodine monochloride, lead dioxide, nitric acid, nitrous acid, organic matter, potassium, and sodium. Avoid contact with water, steam, or acids. Hazardous polymerization may not occur. (EPA, 1998)· EXCEPT FOR ACETIC ANHYDRIDE (UN1715), THAT IS FLAMMABLE, some of these materials may burn, but none ignite readily.· May ignite combustibles (wood, paper, oil, clothing, etc.).· Substance will react with water (some violently), releasing corrosive and/or toxic gases and runoff.· Flammable/toxic gases may accumulate in confined areas (basement, tanks, hopper/tank cars, etc.).· Contact with metals may evolve flammable hydrogen gas.· Containers may explode when heated or if contaminated with water.· Substance may be transported in a molten form.Not combustible. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire. |
| 화재 가능성 | Reacts with water to form hydrochloric acid, which reacts with most metals to form flammable hydrogen gas.... Phosphorus trichloride /is/ ... strongly corrosive and may set fire to combustible material /eg fibrous organic matter (wood, etc)/.Not combustible, but if involved in a fire decomposes to produce hydrogen chloride, phosphoric acid, phosphine.Not combustible. Many reactions may cause fire or explosion. |
| 건강 유해성 | This material is highly toxicit may cause death or permanent injury. Contact is highly irritating to the skin, eyes, and mucous membranes, and the material is an irritant through oral and inhalation exposure. (EPA, 1998)· CORROSIVE and/or TOXICinhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death.· Fire will produce irritating, corrosive and/or toxic gases.· Reaction with water may generate much heat that will increase the concentration of fumes in the air.· Contact with molten substance may cause severe burns to skin and eyes.· Runoff from fire control or dilution water may cause environmental contamination. |
| 유해성 요약 | Liquid causes second or third degree burns after short contact[CHRIS] Highly corrosive to skin[Quick CPC] Rats develop nephrosis and pulmonary edema after 4 hour exposures in the range of 100 ppm23 workers exposed to 1.8 to 27 ppm complained of eye and throat irritationmild bronchitis was common and irritant asthma developed in some of the workers[ACGIH] Toxic to the liver in a chronic study of animals[Desai, H. Phosphorus and Phosphorus Compounds. In: Sullivan J, Krieger G (eds).Hazardous Materials Toxicology.Baltimore:Williams & Wilkins,1992939] A corrosive substance that can cause pulmonary edema[ICSC] A lachrymator[CHEMINFO] |
| 운송 번호 및 가이드(DOT) | 1809 137 |
| 반응성 그룹 | Acids, Strong Non-oxidizingReducing Agents, Strong |
| EC 분류 | Symbol: T+, CR: 14-26/28-35-48/20S: (1/2)-7/8-26-36/37/39-45 |
| UN 분류 | UN Hazard Class: 6.1UN Subsidiary Risks: 8UN Pack Group: I |
| 소화 | Spray cooling water on containers that are exposed to flames until well after fire is out. Do not get water inside containers.This material will not burn. Use carbon dioxide or dry chemical on fires involving phosphorus trichloride. Do not use water. (EPA, 1998)NO hydrous agents. NO water. In case of fire in the surroundings, use appropriate extinguishing media. In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water. |
| 응급 조치 | Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Rinse mouth. Do NOT induce vomiting. Refer for medical attention . |
| 누출 비상 조치 | · CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· Keep unauthorized personnel away.· Stay upwind, uphill and/or upstream.· Ventilate closed spaces before entering, but only if properly trained and equipped.· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.· Stop leak if you can do it without risk.· Use water spray to reduce vaporsdo not put water directly on leak, spill area or inside container.· Keep combustibles (wood, paper, oil, etc.) away from spilled material.Small Spill· Cover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain.· Use clean, non-sparking tools to collect material and place it into loosely covered plastic containers for later disposal.· Prevent entry into waterways, sewers, basements or confined areas. |
| 응급 처치 | Warning: Phosphorus trichloride is a corrosive agent. Contact with eyes may result in severe damage to the cornea, conjunctiva, and blood vessels. Caution is advised.Signs and Symptoms of Phosphorus Trichloride Exposure: Acute exposure to phosphorus trichloride may result in irritation and burning of the skin, eyes, and mucous membranes. Light- headedness, drowsiness, slurred speech, pupillary dilation, increased salivation, dysphagia (difficulty swallowing), abdominal pain, and spontaneous vomiting may occur. Stridor (high-pitched, noisy respirations), dyspnea (shortness of breath), and pulmonary edema are also common. Apathy and mental confusion may develop, with progression to coma and death.Emergency Life-Support Procedures: Acute exposure to phosphorus trichloride may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.Inhalation Exposure:1. Move victims to fresh air. Emergency personnel should avoid self-exposure to phosphorus trichloride.2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.4. Transport to a health care facility.Dermal/Eye Exposure:1. Remove victims from exposure. Emergency personnel should avoid self-exposure to phosphorus trichloride.3. Remove contaminated clothing as soon as possible.4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 30 minutes.5. Wash exposed skin areas thoroughly with water.6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.7. Transport to a health care facility.Ingestion Exposure:1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.2. DO NOT induce vomiting or attempt to neutralize!General First Aid:· Call 911 or emergency medical service.· Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.· Move victim to fresh air if it can be done safely.· Administer oxygen if breathing is difficult.· If victim is not breathing:-- DO NOT perform mouth-to-mouth resuscitationthe victim may have ingested or inhaled the substance.-- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).-- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.· Remove and isolate contaminated clothing and shoes.· For minor skin contact, avoid spreading material on unaffected skin.· In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.· For severe burns, immediate medical attention is required.· Effects of exposure (inhalation, ingestion, or skin contact) to substance may be delayed.· Keep victim calm and warm.· Keep victim under observation.· For further assistance, contact your local Poison Control Center.· Note: Basic Life Support (BLS) and Advanced Life Support (ALS) should be done by trained professionals.Specific First Aid:· For corrosives, in case of contact, immediately flush skin or eyes with running water for at least 30 minutes. Additional flushing may be required.(General first aid procedures)Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.Skin: Water flush immediately - If this chemical contacts the skin, immediately flush the contaminated skin with water. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water. Get medical attention promptly.Breathing: Respiratory supportSwallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. |
| 안전 보관 | Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. See Chemical Dangers. Dry. Well closed. Ventilation along the floor. |
| Firefighting Hazards | The vapor is heavier than air ... A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20 °C.Severe health hazard. May be fatal if inhaled ... Corrosive ...Reacts violently with fire extinguishing agents such as water ... Reacts violently with water producing heat and decomposition products including hydrochloric acid and phosphorous acid, causing fire and explosion hazard. |
| 노출 관리 및 개인 보호 | · Wear positive pressure self-contained breathing apparatus (SCBA).· Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE.· Structural firefighters' protective clothing provides thermal protection but only limited chemical protection.TIH (Toxic Inhalation Hazard) - Term used to describe gases and volatile liquids that are toxic when inhaled. Some are TIH materials themselves, e.g., chlorine, and some release TIH gases when spilled in water, e.g., chlorosilanes. [ERG 2016].0.1 [ppm] |
| 소화 절차 | Evacuation: If fire becomes uncontrollable or container is exposed to direct flame - consider evacuation of one-third (1/3) mile radius.If material on fire or involved in fire: Use dry chemical, dry sand, or carbon dioxide. Do not use water on material itself. If large quantities of combustibles are involved, use water in flooding quantites of water. Apply water from as far a distance as possible.... Use water spray to knock down acid vapors.NO hydrous agents. NO water ... |
| 보관 조건 | Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. See Chemical Dangers. Dry. Well closed. Ventilation along the floor.Store in cool, dry, well-ventilated location. Separate from acids, alkalies, organics, alkali metals. |
| 정리 방법 | Environmental considerations: water spill: Neutralize with agricultural lime (CaO), crushed limestone (CaCO3), or sodium bicarbonate (NaCO3). Use mechanical dredges or lifts to remove immobilized masses of pollutant and precipitates. Adjust pH to neutral (pH=7).Environmental considerations: air spill: Apply water spray or mist to knock down vapors. Vapor knockdown water is corrosive or toxic and should be diked for containment.Environmental considerations: land spill: Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash or cement powder. Neutralize with agricultural lime (CaO), crushed limestone (CaCO3), or sodium bicarbonate (NaHCO3).Releases may require isolation or evacuation. Use water spray to cool and disperse vapors and protect personnel.For more Cleanup Methods (Complete) data for PHOSPHORUS TRICHLORIDE (6 total), please visit the HSDB record page. |
| 비화재 누출 대응 | Excerpt from ERG Guide 137 [Substances - Water-Reactive - Corrosive]:Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Use water spray to reduce vaporsdo not put water directly on leak, spill area or inside container. Keep combustibles (wood, paper, oil, etc.) away from spilled material.SMALL SPILL: Cover with DRY earth, DRY sand or other non-combustible material followed with plastic sheet to minimize spreading or contact with rain. Use clean, non-sparking tools to collect material and place it into loosely covered plastic containers for later disposal. Prevent entry into waterways, sewers, basements or confined areas. (ERG, 2024) |
| 처리 방법 | SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air qualitypotential migration in soil or watereffects on animal, aquatic, and plant lifeand conformance with environmental and public health regulations.Spillage should be handled only by an operator wearing full protective clothing and full-face mask/positive-pressure breathing apparatus. Absorbed spillage and residues should be buried in an approved landfill, away from water sources. |
| 표적 장기 | Eyes, skin, respiratory system |
| 유해 작용 | Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.Nephrotoxin - The chemical is potentially toxic to the kidneys in the occupational setting.Dermatotoxin - Skin burns.Lacrimator (Lachrymator) - A substance that irritates the eyes and induces the flow of tears.Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors. |
| 노출 경로 | The substance can be absorbed into the body by inhalation and by ingestion.inhalation, ingestion, skin and/or eye contact |
| 생태독성 발췌 | /AQUATIC SPECIES/ LC100s /of phosphorus trichloride are/ 57 mg/L/7 days /for/ sturgeon /and/ 65 mg/L/48 hr /for/ sturgeon (Acipenser), carp (Cyprinus carpio), perch (Percidae), Esox lucius (northern pike), and Leuciscus leuciscus (dace). NOEC /at/ pH 3.3 to 7.0 /and/ 22 to 24 °C /is/ 10 to 40 mg/L/30 days /for/ sturgeon, carp, perch, Esox lucius and Leuciscus leuciscus./AQUATIC SPECIES/ Aquatic toxicity range: 10 to 100 mg/L. |
| Signs and Symptoms | Sore throat. Cough. Burning sensation. Nausea. Vomiting. Shortness of breath. Laboured breathing. Symptoms may be delayed.Pain. Redness. Blisters. Skin burns.Pain. Redness. Watering of the eyes. Severe deep burns. Loss of vision.Burning sensation. Abdominal pain. Shock or collapse. Further see Inhalation.irritation eyes, skin, nose, throatpulmonary edemaeye, skin burns |
| Human Toxicity Excerpts | /SIGNS AND SYMPTOMS/ The signs of poisoning in 23 workers exposed to phosphorus trichloride at concentrations ranging from 1.8 to 27 ppm. Symptoms included burning eyes and throat, irritation of pharyngeal mucous membranes, and mild bronchitisthese changes occurred within 2 to 6 hours after exposure. Symptoms from subacute poisoning included irritation of the pharynx, coughing, dyspnea, and severe asthmatic bronchitis, which occurred 1 to 8 weeks after exposure. In workers who had at least 1 year exposure, emphysema was sometimes found. Both acute and subacute poisonings were frequently accompanied by fever and moderate leukocytosis and neutrophilia./SIGNS AND SYMPTOMS/ ... The corrosive effect /of phosphorus trichloride/ is complete destruction of skin or mucous membrane. /From table//SIGNS AND SYMPTOMS/ In a report of 17 persons exposed to phosphorus trichloride and its hydration products, those closest to the spill experienced burning eyes, lacrimation, nausea, vomiting, dyspnea, and cough. Pulmonary function tests showed decrements in vital capacity, maximal breathing capacity, and forced expiratory volume in direct correlation to the distance from the accident./SIGNS AND SYMPTOMS/ Phosphorus trichloride will cause severe burns upon direct dermal contact.For more Human Toxicity Excerpts (Complete) data for PHOSPHORUS TRICHLORIDE (13 total), please visit the HSDB record page. |
| Non-Human Toxicity Excerpts | /LABORATORY ANIMALS: Acute Exposure/ /In/ rabbits /on contact of phosphorus trichloride caused/ thickening in skin folds, bleeding /and/ irreversible necrosis in the eye, causing loss of vision.[European Chemicals BureauIUCLID Dataset, Phosphorus trichloride (7719-12-2) (2000 CD-ROM edition). Available from, as of November 03, 2006: http://esis.jrc.ec.europa.eu/]/LABORATORY ANIMALS: Acute Exposure/ Cats and rabbits /were exposed to phosphorus trichloride by/ inhalation. At 0.004 mg/L for 6 hr minor symptoms /were seen/. With 0.01 to 0.02 mg/L no serious symptoms within 1 hr, 0.3 to 0.5 mg/L serious destructions within the first hour /were seen/. With 0.8 mg/L mortality /occurred/ within 5 to 36 hr, with 3.5 mg/L within 3 hr. Effects /included/ salivation, rhinitis, dyspnea, conjunctivitis, corneal opacities, edema of the respiratory tract.[European Chemicals Bureau/LABORATORY ANIMALS: Acute Exposure/ ... Working with cats & guinea pigs /investigators/ found that a concentration of 0.7 ppm produced only slight illness in 6 hr. 2 to 4 ppm did not produce severe symptoms in 1 hr, but serious disturbances resulted from 1 hr at 50 to 90 ppm. Effects of phosphorous trichloride were considered 5 to 10 times as intense as would result from hydrogen chloride produced by hydrolysis.[American Conference of Governmental Industrial Hygienists. Documentation of the TLV's and BEI's with Other World Wide Occupational Exposure Values. CD-ROM Cincinnati, OH 45240-1634 2005., p. 1]/LABORATORY ANIMALS: Acute Exposure/ Expt in cats concn of 2 to 4 ppm in air in course of 6 hr has caused resp difficulty and conjunctivitis. At 23 to 90 ppm in air in course of 6 hr corneas became clouded and systemic effects were severe.[Grant, W.M. Toxicology of the Eye. 3rd ed. Springfield, IL: Charles C. Thomas Publisher, 1986., p. 736]For more Non-Human Toxicity Excerpts (Complete) data for PHOSPHORUS TRICHLORIDE (14 total), please visit the HSDB record page. |
| Populations at Special Risk | ... People with pre-existing respiratory disease /should/ not work with respiratory irritants such as phosphorus trichloride ... |
| Antidote and Emergency Treatment | Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Chlorine and related compounds/Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Chlorine and related compounds/Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Administer activated charcoal ... . If product was ingested, protect yourself from contact with vomitus as it may cause burns. /Phosphorus and related compounds/Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam or lorazepam ... . Monitor for signs of hypoglycemia (decreased LOC, tachycardia, pallor, dilated pupils, diaphoresis, and/or dextrose stick or glucometer readings below 50 mg/dl) and administer 50% dextrose if necessary. Draw blood sample before administration ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Phosphorus and related compounds/For more Antidote and Emergency Treatment (Complete) data for PHOSPHORUS TRICHLORIDE (8 total), please visit the HSDB record page. |
| Toxicity Data | LC50 (rat) = 104 ppm/4 hr |
| Non-Human Toxicity Values | LD50 Rat oral 550 mg/kgLC50 Rat inhalation 104 ppm/4 hrLC50 Rat Inhalation 0.592 mg/L/4 hrLC50 Rat inhalation 584 mg/cu m/4 hrFor more Non-Human Toxicity Values (Complete) data for PHOSPHORUS TRICHLORIDE (7 total), please visit the HSDB record page. |
| CERCLA 보고 수량 | Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 1000 lb or 454 kg. The toll free number of the NRC is (800) 424-8802. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).Releases of CERCLA hazardous substances are subject to the release reporting requirement of CERCLA section 103, codified at 40 CFR part 302, in addition to the requirements of 40 CFR part 355. Phosphorus trichloride is an extremely hazardous substance (EHS) subject to reporting requirements when stored in amounts in excess of its threshold planning quantity (TPQ) of 1,000 lbs. |
| 청정수법 요건 | Phosphorus trichloride is designated as a hazardous substance under section 311(b)(2)(A) of the Federal Water Pollution Control Act and further regulated by the Clean Water Act Amendments of 1977 and 1978. These regulations apply to discharges of this substance. This designation includes any isomers and hydrates, as well as any solutions and mixtures containing this substance. |
| DHS Chemicals of Interest (COI) | Phosphorus trichloride1150003.4845A Commercial Grade |
| 직업 노출 등급(OEB) | B |
| 직업 노출 한계(OEL) | TWA: 0.2 ppm (1.5 mg/m3), STEL: 0.5 ppm (3 mg/m3) |
| 수질 위해 등급(WGK) | 2 |
| 즉시 생명 위험 농도 | 25 ppm |
| TSCA 등재 상태 | TSCA listed |
| RTECS 번호 | TH3675000 |
| 운송 번호(UN) | UN 1809 |
| 관세 코드 | 28121043 |
| 위험 문구(R) | 14-26/28-29-35-48/20-40-37 |
| 위험 표시 | T+,C |
| 안전 문구(S) | 26-36/37/39-45-7/8-43-28 |
| 포장분류 | I |
| 위험 등급 | 6.1Acute Tox. 2 InhalationAcute Tox. 2 OralEye Dam. 1Skin Corr. 1ASTOT RE 2 Inhalation |
| 기존화학 물질 | KE-28723 |
| F 고인화성물질 | 21 |
| 저장 분류 | 6.1B - Non-combustible, acute toxic Cat. 1 and 2very toxic hazardous materials |
| 유해 물질 데이터 | 7719-12-2(Hazardous Substances Data) |
| 함량 및 규제정보 | 물질구분: 사고대비물질혼합물(제품)함량정보: 삼염화 인 및 이를 25% 이상 함유한 혼합물 |
| 유해화학물질 필터링 | 97-1-132 |
| 사고대비 물질 필터링 | 47 |
용도
용도
1、농약\의약 중간체에 많이 사용된다. 글리포세이트, PMIDA, 디프테렉스, 메타미도포스, 아세페이트, kitazine 등 유기인 농약과 티오포스포릴염화물, 옥시염화인, 아인산, 트리페닐포스페이트 등을 제조하는 주요원료 이다. 2、의약공업에서 술파디아진(S.D)과 S.M.D의 생산에 사용된다. 3、 염료공업에서 나프톨류의 종합제로 사용된다.
개요
Phosphorus trichloride, PCl3, is a clear, colorless, fuming, corrosive liquid. It decomposes rapidly in moist air and has a boiling point of about 168°F (75°C). PCl3 is corrosive to skin and tissue and reacts with water to form hydrochloric acid. The TLV is 0.2 ppm, and the IDLH is 50 ppm in air. The four-digit UN identification number is 1809. The NFPA 704 designation is health 4, flammability 0, and reactivity 2. The white section at the bottom of the diamond contains a W with a slash through it, indicating water reactivity. The primary uses are in the manufacture of organophosphate pesticides, gasoline additives, and dyestuffs; as a chlorinating agent; as a catalyst; and in textile finishing. Corrosives in contact with a poison may produce poison gases as the poison decomposes. In responding to an incident involving corrosives, the toxicity of the vapors could be much more of a concern for personnel than the corrosivity. When acids come in contact with cyanide, hydrogen cyanide gas, which is highly toxic, with a TLV of 10 ppm in air, is produced.
용도
Phosphorus trichloride is an important intermediate in the production of insecticides, herbicides, and organophosphorus pesticides as well as other chemicals such as phosphoryl chloride, phosphorus pentachloride, thiophosphoryl chloride, and phosphonic acid. It is also used in the production of synthetic surfactants, phosphites, gasoline additives, flame retardants, silver polish, and producing iridescent metallic deposits.
제조 및 합성 방법
생산 방법
Phosphorus trichloride (PCl3) is made by reacting yellow phosphorus with chlorine and is used in chemical manufacturing. It hydrolyzes to phosphoric acid and hydrochloric acid.