Calcium Sulfate｜Huagongshe

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HCID 24497생성일: 2026년 10월 26일

Calcium Sulfate

https://huagongshe.com/ko/chemical/24497

Calcium Sulfate 분자 구조식

식별자 및 물리적 특성

CAS No.	14798-04-0
분자식	CaSO4
평균 분자량	136.14 g/mol
단동위원소 질량	135.91432046 g/mol
SMILES	O=S(=O)([O-])[O-].[Ca+2]
InChIKey	OSGAYBCDTDRGGQ-UHFFFAOYSA-L
PubChem CID	24497
ChEMBL	CHEMBL2106140
ChEBI	CHEBI:31346
EC No.	231-900-3
DTXSID	DTXSID9029699

화학 및 물리적 성질

극성 표면적	88.6
수소 결합 공여자 수	0
수소 결합 수용자 수	4
회전 가능 결합 수	0
무거운 원자 수	6
형식 전하	0
복잡도	62.2
물질 분류	Mineral Dusts -> Other Mineral Dusts
Polymers	Plastics -> Pigments agentsPlastics -> N.a.
화장품	BulkingPearlescentOpacifyingAbrasiveCosmetic colorant
냄새	PURE ANHYDROUS CALCIUM SULFATE IS ODORLESSOdorless.
식품 첨가물	ANTICAKING AGENT OR FREE-FLOW AGENT, DRYING AGENT, FORMULATION AID, LEAVENING AGENT, LUBRICANT OR RELEASE AGENT, MALTING OR FERMENTING AID, NUTRIENT SUPPLEMENT, PH CONTROL AGENT, PROCESSING AID, STABILIZER OR THICKENER -> FDA Substance added to food
밀도	2.96 (NIOSH, 2024) - Denser than waterwill sink2.9602.9 g/cm³
Color/Form	NATURAL ANHYDRITE CRYSTALS ARE COLORLESS, RHOMBIC OR MONOCLINICNATURAL ANHYDRITE CRYSTALS ARE ORTHORHOMBIC, COLOR VARIES (WHITE WITH BLUE, GRAY OR REDDISH TINGE, OR BRICK RED)INSOL ANHYDRITE HAS SAME CRYSTAL STRUCTURE AS MINERAL ANHYDRITESOL ANHYDRITE IS OBTAINED IN GRANULAR OR POWDER FORMFor more Color/Form (Complete) data for CALCIUM SULFATE (7 total), please visit the HSDB record page.
용해도	0.3 % (NIOSH, 2024)Slightly soluble in water, insoluble in ethanolFor more Solubility (Complete) data for CALCIUM SULFATE (6 total), please visit the HSDB record page.
끓는 점	Decomposes (NIOSH, 2024)
Decomposition	1450 °C
녹는점	2840 °F (Decomposes) (NIOSH, 2024)1450 °C2840 °F (decomposes)
증기압	0 mmHg (approx) (NIOSH, 2024)

안전 및 규제

GHS 분류	This chemical does not meet GHS hazard criteria for 93.5% (1291 of 1381) of all reports.Not ClassifiedAggregated GHS information provided per 1381 reports by companies from 10 notifications to the ECHA C&L Inventory.WarningH335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]
규제 정보	Chemical: Sulfuric acid, calcium salt (1:1)Regulation (EC) No 1333/2008 (amended)Sulfuric acid, calcium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Sulfuric acid, calcium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 21-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15878Calcium sulfate: Does not have an individual approval but may be used under an appropriate group standard
기타 안전 정보	IMAP assessments - Sulfuric acid, calcium salt (1:1): Human health tier I assessment
화재 위험	Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.
건강 유해성	Excerpt from NIOSH Pocket Guide for Calcium sulfate:
유해성 요약	TLV based on nasal symptoms. Calcium sulfate is a relatively non-toxic substance. Human epidemiologic studies were lacking in exposure information or were confounded by quartz exposure. [ACGIH] See Calcium sulfate dihydrate.
FDA 요건	Substance added directly to human food affirmed as generally recognized as safe (GRAS).Calcium sulfate used as a nutrient and/or dietary supplement in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
반응성 그룹	Salts, Basic
FIFRA 요건	As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Pesticides for which EPA had not issued Registration Standards prior to the effective date of FIFRA, as amended in 1988, were divided into three lists based upon their potential for human exposure and other factors, with List B containing pesticides of greater concern and List D pesticides of less concern. Calcium sulfate is found on List D. Case No: 4055

Reactivity Profile

CALCIUM SULFATE is non-combustible. Decomposes to give toxic oxides of sulfur, but only at very high temperature (>1500 °C). Generally of low reactivity but may act as an oxidizing agent: incompatible with diazomethane, aluminum, and phosphorus. Certain forms of calcium sulfate react with waterothers do not. INSOLUBLE ANHYDRITE or dead-burned gypsum is made by the dehydration of calcium sulfate dihydrate (gypsum) at high (> 600 °C) temperature. At room temperature, insoluble anhydrite dissolves very slowly to the extent of 0.24 g per 100 g of water and does not absorb moisture from the air. SOLUBLE ANHYDRITE, which is obtained by heating calcium sulfate dihydrate at a temperature below 300 °C, has a high affinity for water and is used as a desiccant. Soluble anhydrite absorbs water to form calcium sulfate hemihydrate (Plaster of Paris).

응급 조치	Fresh air, rest.Rinse and then wash skin with water and soap.First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Rinse mouth. Give one or two glasses of water to drink.

처리 방법	SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

누출 처리	Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting.

Preventive Measures

DUST FORMATION IN GYPSUM PROCESSING SHOULD BE CONTROLLED BY MECHANIZATION OF DUSTY OPERATIONS ... ADDITION OF UP TO 2% BY VOL OF WATER TO GYPSUM PRIOR TO CRUSHING, USE OF PNEUMATIC CONVEYORS WITH COVERS & DUST TRAPS, ENCLOSURE OF DUST SOURCES & PROVISION OF EXHAUST SYSTEMS ... . /GYPSUM/GOOD HOUSEKEEPING & MAINTENANCE ARE ESSENTIAL IN PREVENTING ACCUMULATION OF DEPOSITED DUST, & IT IS ADVISABLE IN WORKSHOPS CONTAINING THE CALCINING KILNS, TO FACE WALLS & FLOORS WITH SMOOTH MATERIALS TO FACILITATE CLEANING. /GYPSUM/

Natural Pollution Sources

NATURAL FORM OF ANHYDROUS CALCIUM SULFATE IS KNOWN AS MINERAL ANHYDRITEALSO AS KARSTENITE, MURIACITE, ANHYDROUS SULFATE OF LIME, ANHYDROUS GYPSUM.MINERAL WITH CHEM COMPOSITION CASO4.2H2O. ... IT IS RARELY FOUND PURE & GYPSUM DEPOSITS MAY CONTAIN QUARTZ, PYRITES, CARBONATES & CLAYEY & BITUMINOUS MATERIALS. IT OCCURS IN NATURE IN 5 VARIETIES: GYPSUM ROCKGYPSITE ... ALABASTER ... SATIN SPAR ... & SELENITE. /GYPSUM/Calcium sulfate is the commonest of the natural sulfates.Domestic resources are adequate but are unevenly distributed. There are no gypsum deposits on the eastern seaboard of the United States. Large deposits occur in the Great Lakes region, mid-continent region, California, and other States. /Gypsum/

Human Toxicity Excerpts

GYPSUM DUST HAS AN IRRITANT ACTION ON MUCOUS MEMBRANES OF THE RESPIRATORY TRACT & EYES, & THERE HAVE BEEN REPORTS OF CONJUNCTIVITIS, CHRONIC RHINITIS, LARYNGITIS, PHARYNGITIS, IMPAIRED SENSE OF SMELL & TASTE, BLEEDING FROM THE NOSE, & REACTIONS OF TRACHEAL & BRONCHIAL MEMBRANES IN EXPOSED WORKERS. /GYPSUM/Because it hardens quickly after absorbing moisture, its ingestion may result in obstruction, particularly at the pylorus. ... To delay "setting," drink glycerin or gelatin solutions, or large volumes of water. Surgical relief may be necessary. /Plaster of Paris/... Calcium sulfate caused no lung disease in calcium sulfate miners.

Non-Human Toxicity Excerpts

EXPTL ANIMALS EXPOSED TO GYPSUM DUST DEVELOPED PNEUMONIA & INTERSTITIAL PNEUMOSCLEROSIS, & BLOOD & LYMPH CIRCULATION DISORDERS OCCURRED IN THE LUNGS. /GYPSUM/Applied experimentally to rabbit eyes it has been found innocuous.Six types of man-made fibers were administered intratracheally 12.0 mg/animal each a week for 5 weekstotal 10 mg/animal) to female Syrian hamsters that were observed histologically for 2 years after administration. The fibers were rock wool [average diameter (D) = 6.1 microns, average length (L) = 296 microns], fiberglass (D = 0.65 microns, L = 16.8 microns), potassium titanate fiber ID = 0.36 microns, L = 7.17 microns), calcium sulfate fiber (D = 1.0 microns, L = 17.8 microns), basic magnesium sulfate fiber ID = 0.45 microns, L = 22.4 microns), and metaphosphate fiber (D = 2.38 microns, L = 64.1 microns). Tumors were observed in hamsters that had received basic magnesium sulfate fiber (9/20), metaphosphate fiber (6/20), calcium sulfate fiber (3/20), and fiberglass (2/20) but not in the control, rock wool, or potassium titanate fiber groups. The primary sites of the tumors were not only in the pleural cavity but also in the intracelial organs, kidney, adrenal gland, bladder, and uterus. Only a few of the tumors were identified as mesotheliomas by histological examination. In addition to neoplastic lesions, fibrosis, pleural thickening, and chronic inflamatory changes in the lungs were observed in the hamsters, but these changes appeared too mild to foster a pneumoconiosis such as asbestos.The genotoxicity of selenite was investigated in two diploid yeast strains Saccharomyces cerevisiae BZ34 and D7. The effect of reduced glutathione (GSH) on the genotoxicity of selenite in the BZ34 strain was also examined. Selenite induced gene conversion and toxicity in the BZ34 strain. A variety of genetic events occurred including back mutation gene conversion mitotic crossing over aberrant colony formation and toxicity in another strain D7. The genetic activity of selenite peaked at one hour and subsequently declined when the two higher concentrations, (1O(-3) and 10(-2) molar), of selenite were used. When treatment was continued beyond 1 hr the percent of survival decreased marginally. Yeast cells may cause metabolic deactivation of selenite during 5 hr of treatment as the genetic and toxic effects of selenite beyond 1 hr begin to decline. When glutathione was present during the selenite treatment the convertogenic and toxic effects of selenite were significantly enhanced.

Probable Routes of Human Exposure	WORKERS EMPLOYED IN PROCESSING OF GYPSUM ROCK MAY BE EXPOSED TO HIGH ATMOSPHERIC CONCN OF GYPSUM DUST ... FURNACE GASES & SMOKE. IN GYPSUM CALCINATING, WORKERS ARE EXPOSED TO HIGH ENVIRONMENTAL TEMP, & THERE IS ALSO THE HAZARD OF BURNS. /GYPSUM/