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Cosmetic ingredients (Glycol Stearate) -> CIR (Cosmetic Ingredient Review)

Cosmetic ingredients (Glycol Stearate SE) -> CIR (Cosmetic Ingredient Review)

Emollient; Opacifying; Surfactant; Humectant; Emulsifying

POLYETHYLENE GLYCOL ESTERS AND ETHERS INCR THE WATER SOLUBILITY OF TYROTHRICIN.

SOL IN CARBON TETRACHLORIDE, PETROLEUM BENZIN, CHLOROFORM, ETHER; SLIGHTLY SOL IN ALCOHOL; INSOL IN WATER /POLYETHYLENE GLYCOL 400 MONOSTEARATE USP XVI/

GENERALLY SOL OR DISPERSIBLE IN WATER

SOL IN TOLUENE, ACETONE, ETHER AND ETHANOL

MP: 30-34 °C /POLYETHYLENE GLYCOL 400 MONOSTEARATE USP XVI/

60.00 to 61.00 °C. @ 760.00 mm Hg

Dry Powder; Other Solid; Large Crystals; Liquid; Liquid

Light tan solid; [Hawley]

NONIONIC SURFACTANT

NEARLY ODORLESS /POLYETHYLENE GLYCOL 400 MONOSTEARATE USP XVI/

This chemical does not meet GHS hazard criteria for 75.2% (357 of 475) of all reports.

Warning

H315 (18.9%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 475 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

This chemical does not meet GHS hazard criteria for 87% (267 of 307) of all reports.

Chemical: Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy-

Chemical: Octadecanoic acid, 2-hydroxyethyl ester

Octadecanoic acid, 2-hydroxyethyl ester is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Octadecanoic acid, 2-hydroxyethyl ester are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

FRI - indicates a polymeric substance containing no free-radical initiator in its Inventory name but is considered to cover the designated polymer made with any free-radical initiator regardless of the amount used.

Octadecanoic acid, 2-hydroxyethyl ester: Does not have an individual approval but may be used under an appropriate group standard

Tegin G: Does not have an individual approval but may be used under an appropriate group standard

Caused bladder stones in rats when fed at >20% of diet; [JECFA] Mild irritant effect in eye of rabbit; [RTECS] Hydrolyzed in the intestines--fatty acids metabolized and the polyoxyethylene residues excreted unchanged in the urine; [HSDB] An irritant; [MSDSonline] See STEARATES.

Chemical: Ethylene glycol monostearate

Chemical: Polyethylene glycol stearate

Skin Irrit. 2 (18.9%)

Eye Irrit. 2 (13%)

8 hr Time Weighted Avg (TWA): 10 mg/cu m. /Stearates; does not include stearates of toxic metals/

Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Stearates; does not include stearates of toxic metals/

A4; Not classifiable as a human carcinogen. /Stearates; does not include stearates of toxic metals/

MYRI 32 INCREASED GI ABSORPTION OF ORAL GENTAMICIN IN RATS.

SENSITIVITY OF FEEDING TESTS IN DETECTING CARCINOGENICITY OF SMALL DOSE OF 7,12-DIMETHYLBENZ[A]ANTHRACENE IN FEMALE RATS INCR WHEN IT WAS GIVEN AT AN EARLIER AGE AND WHEN A HIGH FAT DIET CONTAINING 1% POLYOXYETHYLENE MONOSTEARATE WAS ADMIN.

Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

MALE & FEMALE RATS WERE FED HIGH DOSES OF MYRJ 45 FOR MORE THAN 12 WK, THEN REPRODUCTION & LACTATION WERE MEASURED. A SOMEWHAT GREATER PROP OF INFANT DEATHS NOTED AT 10% LEVEL THAN AT 5% LEVEL, WHEREAS AT 20% LEVEL SIGNIFICANT DIMINUTION OF SURVIVAL OF NEWBORN WAS OBSERVED.

THESE ESTERS ARE HYDROLYZED IN THE BOWEL. THE FATTY ACID IS ABSORBED & METABOLIZED; AT LEAST THE SHORTER POLYOXYETHYLENE RESIDUES ARE ALSO ABSORBED, BUT THEY ARE EXCRETED UNCHANGED IN THE URINE (NO DETECTABLE METABOLISM TO OXALIC ACID IN MAN).

CIR ingredient: Glycol Stearate

CIR ingredient: Glycol Stearate SE

Used as a surfactant, emulsifier (cosmetics, pharmaceuticals, textile finishes, defoamers, and baked goods), dye assistant, lubricant, and antistatic agent; Also used in dentifrice compositions and to make creams, lotions, ointments, and pharmaceutical preparations; [HSDB]

Textiles (Printing, Dyeing, or Finishing) [Category: Industry]

SURFACTANT

PEG 400 MONOSTEARATE USP XVI: IN PREPN OF CREAMS, LOTIONS, OINTMENTS & PHARMACEUTICAL PREPN WHICH ARE SOL IN WATER

2023: 1,000,000 - <2,500,000 lb

(1972) 2.4X10+9 GRAMS (MONOSTEARATE)

(1975) 3.13X10+9 GRAMS (MONOSTEARATES)

(1984) 2.91X10+9 g

Information on 150 consumer products that contain Glycol stearate in the following categories is provided:

Information on 169 consumer products that contain PEG- 100 Stearate in the following categories is provided:

EPA Safer Chemical Functional Use Classes -> Surfactants

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

EPA Safer Chemical Functional Use Classes -> Defoamers;Surfactants

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Cosmetics -> Emollient; Opacifying; Surfactant; Humectant; Emulsifying

Soap, Cleaning Compound, and Toilet Preparation Manufacturing

Octadecanoic acid, 2-hydroxyethyl ester: ACTIVE

Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy-: ACTIVE

POLYETHYLENE GLYCOL 400 MONOSTEARATE USP XVI: IT IS AN ETHER, ALCOHOL & ESTER.