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기본 정보
- CAS
1005780-62-0- 표준 SMILES
Cc1cc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)ccc2C)n(C)n1- InChIKey
DZFZXPPHBWCXPQ-UHFFFAOYSA-N- 분자식
- C23H23N7O3
- 평균 분자량
- 445.5 g/mol
- 단동위원소 질량
- 445.18623762
이름 및 식별자
- 우선 이름
- Tak-593
- IUPAC
- N-[5-[2-(cyclopropanecarbonylamino)imidazo[1,2-b]pyridazin-6-yl]oxy-2-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide
- 영어명
- TAK-593
- 분자식
- C23H23N7O3
- 분자량
- 445.47
이름 및 동의어
TAK-5931005780-62-0TAK 593H3I42X8XX71H-Pyrazole-5-carboxamide, N-(5-((2-((cyclopropylcarbonyl)amino)imidazo(1,2-b)pyridazin-6-yl)oxy)-2-methylphenyl)-1,3-dimethyl-N-[5-({2-cyclopropaneamidoimidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamideTAK593N-(5-((2-cyclopropaneamidoimidazo(1,2-b)pyridazin-6-yl)oxy)-2-methylphenyl)-1,3-dimethyl-1H-pyrazole-5-carboxamideRefChem:187192VEGFR/PDGFR Tyrosine Kinase Inhibitor TAK-593UNII-H3I42X8XX7N-(5-((2-(cyclopropanecarboxamido)imidazo[1,2-b]pyridazin-6-yl)oxy)-2-methylphenyl)-1,3-dimethyl-1H-pyrazole-5-carboxamide
이름 더 보기
TAK-593, 10 mM in DMSO1H-Pyrazole-5-carboxamide, N-[5-[[2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl]oxy]-2-methylphenyl]-1,3-dimethyl-Platelet-derived growth factor receptor,VEGFR,PDGFR,Inhibitor,TAK 593,inhibit,TAK593,TAK-593,Vascular endothelial growth factor receptor
CHEMBL2180604N-[5-[2-(cyclopropanecarbonylamino)imidazo[1,2-b]pyridazin-6-yl]oxy-2-methylphenyl]-2,5-dimethylpyrazole-3-carboxamide1H-Pyrazole-5-carboxamide, N-[5-[[2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl]oxy]-2-methylphenyl]-1,3-dimethyl-;1H-Pyrazole-5-carboxamide, N-[5-[[2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl]oxy]-2-methylphenyl]-1,3-dimethyl-orb1219200orb1307706SCHEMBL2515478DZFZXPPHBWCXPQ-UHFFFAOYSA-NC23H23N7O3
데이터베이스 식별자
- CAS
1005780-62-0- PubChem CID
- 24767976
- ChEMBL
CHEMBL2180604- UNII
- H3I42X8XX7
- Nikkaji
- J3.204.404B
물성
구조 계산 물성보충 중
- XLogP
- 2.4
- 극성 표면적
- 115 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 6
- 회전 가능 결합 수
- 6
- 무거운 원자 수
- 33
- 형식 전하
- 0
- 복잡도
- 735
물리화학적 성질
- 밀도
- 1.46 · 1.46±0.1 g/cm3(Predicted)
- 저장 조건
- -20 °C · Store at -20°C
- 용해도
- DMSO에 용해됨
- 물리적 상태
- Solid
- 산도 계수 (pKa)
- 9.22 · 9.22±0.20(Predicted)
- 색상
- White to light yellow
- InChIKey
- DZFZXPPHBWCXPQ-UHFFFAOYSA-N
- SMILES
- N1(C)C(C(NC2=CC(OC3=NN4C=C(NC(C5CC5)=O)N=C4C=C3)=CC=C2C)=O)=CC(C)=N1
화학 및 산업
공급사26 곳
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
InvivoChem中国13549236410 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
銳迪國際科技有限公司18024082417 · [email protected]
MedChemexpress LLC021-58955995 · [email protected]
武汉壹加壹生物科技有限公司027-027-16602739303 16602739303 · [email protected]
杭州六可生物科技有限公司+86-0571-86912261 +86-15658003402 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
斯派螺（武汉）药物研发有限公司[email protected]
上海阿拉丁生化科技股份有限公司6206333 13167063860 · [email protected]
风咏生物（AbMole）021-10000000 13000000000 · [email protected]
广州市齐云生物技术有限公司020-61288194 61288195 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
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