루굴로신
RUGULOSIN
데이터를 보충하는 중입니다. 잠시 후 페이지를 새로 고치면 최신 내용을 볼 수 있습니다
기본 정보
- CAS
23537-16-8- 표준 SMILES
Cc1cc(O)c2c(c1)C(=O)[C@@]13C(=C2O)C(=O)[C@H]2[C@@H](O)[C@@H]1[C@H]1[C@H](O)[C@@H]3C(=O)C3=C(O)c4c(O)cc(C)cc4C(=O)[C@@]312- 분자식
- C30H22O10
- 평균 분자량
- 542.49 g/mol
이름 및 식별자
- 우선 이름
- RUGULOSIN
- 현지명
- 루굴로신
- 영어명
- RUGULOSIN
- 분자식
- C30H22O10
- 분자량
- 542.49
이름 및 동의어
루굴로신Rugulosin ARUGULOSINNsc160880NSC 249990(+)-Rugulosin(+)-(1S,1'S,2R,2'R,3S,3'S,9AR,9'AR)-RUGULOSINRugulosin ((+)-Rugulosin), RNA polymerase inhibitor(+)-Rugulosin, (1S,1S,2R,2R,3S,3S,9aR,9aR)-Rugulosin, (2R,2R)-Rugulosin5H,6H-6,13A,5A,14-[1,2,3,4]Butanetetraylcycloocta[1,2-B:5,6-B']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-5H,6H-6,13a,5a,14-[1,2,3,4]Butanetetraylcycloocta[1,2-b:5,6-b']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, (5aS,6R,13aS,14R,17S,18R,19R,20S)-
데이터베이스 식별자
- CAS
23537-16-8- PubChem CID
- 24776464
- UNII
- 7020AB775D
- Nikkaji
- J34.118E
물성
물리화학적 성질
- 녹는점
- 293 ℃ · 293℃ (decomposition)
- 끓는 점
- 535.95 °C · 535.95°C (rough estimate)
- 밀도
- 1.3164 · 1.3164 (rough estimate)
- 굴절률
- 1.5376 · 1.5376 (estimate)
- 저장 조건
- -20 °C · Store at -20°C
- 용해도
- DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- 물리적 상태
- 고체
- 산도 계수 (pKa)
- 4.2 · 4.20±1.00(Predicted)
- EPA
- 5 H,6H-6,13a,5a,14-[1,2,3,4]Butanetetraylcycloocta[1,2-b:5,6-b']dinaphthalene-5,8,13,16 · 5H,6H-6,13a,5a,14-[1,2,3,4]Butanetetraylcycloocta[1,2-b:5,6-b']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, (5aS,6R,13aS,14R,17S,18R,19R,20S)- (23537-16-8)
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- HS 번호
- 29419000
화학 및 산업
응용 분야
개요(+)-Rugulosin is a pigment and mycotoxin produced by certain fungi. It inhibits HIV-1 integrase activity with IC50 values of 19 and 25 μM in coupled and strand transfer assays, respectively. It also inhibits ribonuclease H in rat liver by 83% at a concentration of 157 μM and ribonucleases H1, H2, and H3 in T. pyriformis by 100, 99, and 100%, respectively, at a concentration of 313 μM. (+)-Rugulosin leads to hepatic injury and liver cell hyperplasia in mice when administered in the diet. It is cytotoxic to insect cells but not mammalian C6/36, L929, and HepG2 cells (ID50s = 1.2, >200, 23.7, and >200 μg/ml, respectively).
용도(+)-Rugulosin is an intense yellow pigment produced by some species of Penicillium, Aspergillus and the fungal symbiotants of some lichens. (+)-Rugulosin shows antibacterial and insecticidal activity and has found application as a bioinsecticide, notably as the active secondary metabolite in endophytic fungi of seedlings.
관련 반응
0건
현재 필터 조건에 해당하는 반응 기록이 없습니다.
화합물 노트
불러오는 중…