Ferrous ammonium sulfate

1.86 at 68 °F (USCG, 1999) - Denser than water; will sink

Pale blue-green crystals or crystalline powder. Efforesces. Density: 1.86 at 20 °C/4 °C. /Ferrous ammonium sulfate hexahydrate/

1.865 @25 °C

Ferrous ammonium sulfate appears as a light green crystalline solid. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. It is used in medicine, chemical analysis and metallurgy.

Light green crystals, deliquescent and soluble in water; [CAMEO]

Decomposes at 100 to 110 °C; deliquescent; affected by light. /Ferrous ammonium sulfate hexahydrate/

Blue-green monoclinic crystals. /Ferrous ammonium sulfate hexahydrate/

Sugar, glycerin, & many organic hydroxy acids hinder precipitation. In neutral solution, soluble carbonates, phosphates, & oxalates produce precipitation. /Ferrous salts/

This chemical does not meet GHS hazard criteria for 98.3% (171 of 174) of all reports.

Not Classified

Aggregated GHS information provided per 174 reports by companies from 5 notifications to the ECHA C&L Inventory.

Chemical: Sulfuric acid, ammonium iron(2+) salt (2:2:1)

Status: Active Update: 09-12-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/24000

Restricted substance: Diammonium iron bis(sulphate)

Sulfuric acid, ammonium iron(II) salt: Does not have an individual approval but may be used under an appropriate group standard

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Pesticides for which EPA had not issued Registration Standards prior to the effective date of FIFRA '88 were divided into three lists based upon their potential for human exposure and other factors, with List B containing pesticides of greater concern and List D pesticides of less concern. Ferrous ammonium sulfate is found on List D. Case No: 4058; Pesticide type: herbicide; Case Status: //csrc//; Active ingredient (AI): ferrous ammonium sulfate; AI Status: The active ingredient is no longer contained in any registered products ... "cancelled."

Environmental considerations: Water spill: Allow to aerate. Neutralize with agricultural lime (CaO), crushed limestone (CaCO3), or sodium bicarbonate (NaHCO3). Adjust pH to neutral (pH+ 7). Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.

Environmental considerations: Land spill: Big a pit, pond, lagoon, holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Cover soldis with a plastic sheet to prevent dissolving in rain or fire fighting water.

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

The following wastewater treatment technologies have been investigated for iron (Fe+2): Concentration process: Biological treatment. /Iron (Fe+2)/

SRP: Local exhaust ventilation should be applied wherever there is an incidence of point source emissions or dispersion of regulated contaminants in the work area. Ventilation control of the contaminant as close to its point of generation is both the most economical and safest method to minimize personnel exposure to airborne contaminants.

SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at end of shift, but should remain at employee's place of work for cleaning.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Remove contaminated clothing and shoes.

For more Preventive Measures (Complete) data for FERROUS AMMONIUM SULFATE (7 total), please visit the HSDB record page.

1.0 [mg/m3], as Fe (soluble iron salts)

8 hr Time Weighted Avg (TWA) 1 mg/cu m /Iron salts, soluble, as Fe/

Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Iron salts, soluble, as Fe/

15 [mg/m3]

78 [mg/m3]

470 [mg/m3]

Dust mask; goggles or face shield; protective gloves (USCG, 1999)

Dust mask; goggles or face shield; protective gloves. /Ferrous ammonium sulfate hexahydrate/

/ALTERNATIVE IN VITRO TESTS/ The effect of vitamin E deficiency on brain mitochondrial oxidative phosphorylation was studied using brain mitochondria isolated from control and vitamin E-deficient rats (13 months of deficiency) after exposure to iron, an inducer of oxidative stress. Mitochondria were treated with iron (2 to 50 microM) added as ferrous ammonium sulfate. Rates of state 3 and state 4 respiration, respiratory control ratios, and /the ratio of ADP molecules phosphorylated to oxygen atoms reduced/ (ADP/O) were not affected by vitamin E deficiency alone. However, iron uncoupled oxidative phosphorylation in vitamin E deficient mitochondria, but not in controls. In vitamin E deficient mitochondria, iron decreased ADP/O ratios and markedly stimulated state 4 respiration; iron had only a modest effect on these parameters in control mitochondria. Thus, vitamin E may have an important role in sustaining oxidative phosphorylation. Low concentrations of iron (2 to 5 microM) oxidized mitochondrial tocopherol that exists in two pools. The release of iron in brain may impair oxidative phosphorylation, which would be exacerbated by vitamin E deficiency.

Maintain an open airway and assist ventilation if necessary. Treat shock caused by hemorrhagic gastrointestinitis aggressively with intravenous crystalloid fluids, and replace blood if needed. Patients are often markedly hypovolemic owing to gastrointestinal losses and third spacing of fluids into the intestinal wall and interstitial space. Treat coma, seizures, and metabolic acidosis if they occur. For seriously intoxicated victims (eg, shock, severe acidosis, and/or serum iron > 500-600 mcg/dL) administer deferoxamine. Monitor the urine for the urine for the characteristic orange or pink deferoxamine-iron complex. Therapy may be stopped when the urine returns to normal or when the serum iron level decreases to the normal range. Prolonged deferoxamine has been associated with adult respiratory distress syndrome and Yersinia sepsis.

Activated charcoal is not effective. Ipecac is not recommended, because it can aggravate iron-induced gastrointestinal irritation and interfere with whole bowel irrigation. Consider gastric lavage if product was a liquid formulation or tablets were chewed. Do-not use phosphate-containing solutions for lavage; these may result in life-threatening hypernatremia, hyperphosphatemia, and hypocalcemia. Bicarbonate and deferoxamine lavage are of doubtful efficacy. Deferoxamine lavage is not effective and may enhance iron absorption. Whole-bowel irrigation is very effective for ingested tablets and may be considered first-line treatment, especially if large numbers of tablets are visible on plain abdominal x-ray. Massive ingestions may lead to concretions or bezoars. Repeated or prolonged whole-bowel irrigation may remove tablets. Endoscopy or surgical gastrotomy is rarely required.

Hemodialysis and hemoperfusion are not effective for removing iron but may be necessary to remove iron-deferoxamine complex in patients with renal failure. Exchange transfusion is occasionally used for massive pediatric ingestions but is of questionable efficacy.

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. /Iron and related compounds/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with lactated Ringer's /SRP: "To keep open", minimal flow rate/. Watch for signs of fluid overload. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Iron and related compounds/

LD50 Rat ingestion 0.5-5 g/kg

LD50 Rat oral 3,250 mg/kg bw /Hexahydrate/

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Pesticides for which EPA had not issued Registration Standards prior to the effective date of FIFRA '88 were divided into three lists based upon their potential for human exposure and other factors, with List B containing pesticides of greater concern and List D pesticides of less concern. Ferrous ammonium sulfate is found on List D. Case No: 4058; Pesticide type: herbicide; Case Status: //csrc//; Active ingredient (AI): ferrous ammonium sulfate; AI Status: The active ingredient is no longer contained in any registered products ... "cancelled."

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 1000 lb or 454 kg. The toll free number of the NRC is (800) 424-8802; In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).

Ferrous ammonium sulfate is designated as a hazardous substance under section 311(b)(2)(A) of the Federal Water Pollution Control Act and further regulated by the Clean Water Act Amendments of 1977 and 1978. These regulations apply to discharges of this substance. This designation includes any isomers and hydrates, as well as any solutions and mixtures containing this substance.

The pharmacokinetics and bioavailability of iron following the oral administration of Vitaferro to normal and anemic women in their second half of pregnancy and to nonpregnant women are described. In all pregnant probands the bioavailability of the drug was about twice as high as in nonpregnant women. The parameters of elimination refer to an enhanced retention of iron during pregnancy. The drug was well resorbed and did not cause incompatibilities.

Used in medicine, metallurgy, and chemical analysis; [CAMEO] Also used in photography, iron-plating baths, and as a polymerization catalyst; Approved for use in the production of cellophane for food packaging; [HSDB]

Photographic Processing [Category: Other]

The active ingredient is no longer contained in any registered products ... "cancelled."

For ferrous ammonium sulfate (USEPA/OPP Pesticide Code: 050506) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./

In photography; as analytical standard; as polymerization catalyst; in dosimeters. /Ferrous ammonium sulfate hexahydrate/

Analytical chemistry; metallurgy. /Ferrous ammonium hexahydrate/

Mfr from iron, sulfuric acid, & ammonia.

By mixing solutions of ferrous sulfate & ammonium sulfate, followed by evaporation & subsequent crystallization. /Ferrous ammonium sulfate hexahydrate/

The fertilizer grade contains 14% ferrous iron, 7% nitrogen, and 16% sulfur. /Ferrous ammonium sulfate hexahydrate/

Technical, 99-102%; reagent. /Ferrous ammonium sulfate hexahydrate/

Sulfuric acid, ammonium iron(2+) salt (2:2:1): ACTIVE

Lawn moss control with ferric ammonium sulfate-ammonium sulfate double salts was studied.