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Trenbolone

HCID 25015
노트반응
기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
10161-33-8
표준 SMILES
C[C@]12C=CC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@H]2O
InChIKey
MEHHPFQKXOUFFV-OWSLCNJRSA-N
분자식
C18H22O2
평균 분자량
270.4 g/mol
단동위원소 질량
270.16197994

개요

Trenbolone is a 3-oxo-4 steroid that is estra-4,9,11-triene carrying an oxo group at position 3 and a hydroxy group at position 17beta. It is a synthetic anabolic steroid used for muscle growth in livestock. It has a role as an endocrine disruptor and a plant metabolite. It is a C18-steroid, a 17beta-hydroxy steroid, a 3-oxo-Delta(4) steroid and an anabolic androgenic steroid.

이름 및 식별자

우선 이름
Trenbolone
IUPAC
(8S,13S,14S,17S)-17-hydroxy-13-methyl-2,6,7,8,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-one
영어명
Trenbolone
분자식
C18H22O2
분자량
270.37

이름 및 동의어

Trenbolone10161-33-817beta-TrenboloneTrienbolone(+)-Trenbolone17-beta-TrenboloneTrenbolonum17-beta-Hydroxyestra-4,9,11-trien-3-oneDTXSID0034192RU 2341P53R4420TRDTXCID8014192
이름 더 보기
trenbolon17β-TrenboloneParabolaTrenbolone enthanatetrenbolone (17β-hydroxyestr-4,9,11-trien-3-one)R 2580ru2341Tren 100
CHEBI:35018RU-2341trenbolonaRefChem:6506beta-Trenbolone17|A-TrenboloneTrembolona(8S,13S,14S,17S)-17-hydroxy-13-methyl-2,6,7,8,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-one

데이터베이스 식별자

CAS
10161-33-8
PubChem CID
25015
DTXSID
DTXSID0034192
ChEMBL
CHEMBL197309、CHEMBL3182355
ChEBI
CHEBI:35018
UNII
P53R4420TR
EC Number
600-229-1
Nikkaji
J8.986I

물성

구조 계산 물성

XLogP
1.9
극성 표면적
37.3 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
2
회전 가능 결합 수
0
무거운 원자 수
20
형식 전하
0
복잡도
566

실험 및 물리화학적 성질

Drugs · 3건

DEA NFLIS-Drug Category -> Steroids

Pharmaceutical

Pharmaceuticals -> Synthetic Cannabinoids or Psychoactive Compounds

Human DrugsPharmaceuticals
Endocrine DisruptorsPotential endocrine disrupting compound
Collision Cross Section · 2건

192.3 Ų [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID0034192]

163.3 Ų [M+H]+ [CCS Type: TW]

물리화학적 성질

녹는점
170 °C · 170°C
끓는 점
490.8 · 490.8±45.0 °C(Predicted)
밀도
1.19 · 1.19±0.1 g/cm3(Predicted)
인화점
2 ℃ · 2℃
저장 조건
2 · 2-8°C
용해도
30 mg/ml; · DMF: 30 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml
물리적 상태
liquid
산도 계수 (pKa)
14.73 · 14.73±0.40(Predicted)
주요 응용
임상 시험
InChI
InChI=1/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h8-10,15-17,20H,2-7H2,1H3/t15-,16+,17+,18+/s3
InChIKey
MEHHPFQKXOUFFV-OWSLCNJRSA-N
SMILES
[C@@]12([H])CC[C@H](O)[C@@]1(C)C=CC1=C3CCC(=O)C=C3CC[C@@]21[H] |&1:0,4,6,20,r|
EPA
-4 · Estra-4,9,11-trien-3-one, 17-hydroxy-, (17.beta)- (10161-33-8)

화학적 성질

Yellow Solid

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 4건

Danger

H360 (95.9%): May damage fertility or the unborn child [Danger Reproductive toxicity]

P203, P280, P318, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 74 reports by companies from 6 notifications to the ECHA C&L Inventory.

유해성 정보

Regulatory InformationREACH registered substance: (8S,13S,14S,17S)-17-hydroxy-13-methyl-2,6,7,8,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-one (EC: 600-229-1)
Hazard Classes and CategoriesRepr. 1A (95.9%)

안전 데이터

wgk
3
rtecs
KG7752000
ridadr
UN 1648 3 / PGII
risk_code
60-36-20/21/22-11
hazard_code
T,Xn,F
safety_code
53-22-36/37/39-45-36/37-26-16
Hazard Classifications
Acute Tox. 4 DermalAcute Tox. 4 InhalationAcute Tox. 4 OralEye Irrit. 2Flam. Liq. 2
스토리지 클래스
3 - Flammable liquids

화학 및 산업

약리 정보

MeSH Pharmacological ClassificationThese compounds stimulate anabolism and inhibit catabolism. They stimulate the development of muscle mass, strength, and power.

용도 및 제조

Use ClassificationPharmaceuticals
응용 분야 · 2건

개요Trenbolone, also known as trienolone or trienbolone, is a kind of anabolic androgenic steroid belonging to the 19-nortestosterone group. It can be supplied to veterinary medicine of livestock in order the boost muscle growth and appetite. It can also enhance the performance of athletes. It has several physiological effects: (1) enhance protein synthesis and nitrogen retention in the muscle tissues, which boost enhanced anabolism; (2) greatly promote insulin-like growth factor-1 (IGF-1) which is a highly effective anabolic hormone; (3) Greatly increase the red blood cell count to boost blood oxygenation which leads to improved muscular endurance; (4) Inhibit glucocorticoid hormones which inhibit the growth of muscle tissue and promote fat. (5) Improve food efficiency.

용도Trenbolone is a controlled substance (anabolic steroid). It is a steroid used on livestock to increase muscle growth and appetite. To increase its effective half-life, trenbolone is administered as a prodrug as an ester conjugate such as [trenbolone acetate], trenbolone enanthate, or trenbolone cyclohexylmethylcarbonate. Plasma lipases then cleave the ester group in the bloodstream leaving free trenbolone.

상·하류 제품 정보

상류 원료

무수초산메틸 옥시레인, 중합체 ,함유 옥시레인, 에테르 ,함유 (1,2-에탄딜- 디니트리로)테트라키스(프로판올)Sodium tert-pentoxide메틸알콜아세트산(빙초산)

하류 제품

유행

공급사100 곳

北京华美互利生物化工010-56205725 · [email protected]
Shanghai Biolang Biotechnology Co., Ltd.+86-15970428662 +86-13397199602 · [email protected]
济南百隆化学有限公司[email protected] · [email protected]
艾吉析科技(上海)有限公司17717235263 · [email protected]
广州佳途科技股份有限公司81960175-877 18933936954 · [email protected]
陕西帕尼尔生物科技有限公司029-84385017-8003 13259417953 · [email protected]
长沙畋阳生物科技有限公司19558384994 19558384994 · [email protected]
广州隽唐科技有限公司020-36607679 13502246435 · [email protected]
南京世洲生物科技有限公司025-025-85560043 17301488900 · [email protected]
上海赛可锐生物科技有限公司021-58000709 13120558703 · [email protected]
武汉绿景丰华生物科技有限公司19972070065 · [email protected]
上海钰源生物化学有限公司021-13814116 13814116708 · [email protected]
陕西林奈生物化工有限公司15327269642 · [email protected]
LGM Pharma1-(800)-881-8210 · [email protected]
河北秒变生物科技有限公司17733850068
上海颖心实验室设备有限公司021-59178156 17002132182 · [email protected]
广东云星生物技术有限公司0751-18902340975/189023400307 18902340307 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
Cangzhou Wanyou New Material Technology Co.,Ltd18631714998 · [email protected]
广东方信生物科技有限公司0751-2838688 13376594225 · [email protected]
InvivoChem中国13549236410 · [email protected]
上海维亦特生物科技有限公司15317051735 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
Zhejiang J&C Biological Technology Co.,Limited+1-2135480471 · [email protected]
浙江佑宁医药有限公司15557595058
云南西力生物技术股份有限公司0871-65217109 · [email protected]
上海毕楷科技有限公司18516304666 · [email protected]
Xiamen AmoyChem Co., Ltd+86-86-5926051114 · [email protected]
陕西康多普生物科技有限公司184-2900-1220 18429001220 · [email protected]
广州普罗艾森生物医药有限公司19098059326 · [email protected]
TOKYO CHEMICAL INDUSTRY CO., LTD.03-36680489 · [email protected]
深圳振强药物研发有限公司0755-66853366 13670046396 · [email protected]
上海诺宝化工有限公司+86(0)21 60484900
南京生利德生物科技有限公司025-57798810 18652991625 · [email protected]
Xunteng International Trading Co.,Limited—
湖北鑫源顺医药化工有限公司13971561712, 13995564702, 027-50664929 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
上海寰川实业有限公司021-61478794 · [email protected]
Taizhou Xinen Biotechnology Co., Ltd.+8615068633455 · [email protected]
青岛海智微元生物科技有限公司18317699790 18317699790 · [email protected]
池州凯隆进出口贸易有限公司[email protected]
ALB Technology Limited702-983-3769 · [email protected]
石家庄通洋进出口有限公司[email protected]
Wuhan Biocar Bio-Pharm Co., Ltd.86 15387057351 · [email protected]
广东泰博医药科技有限公司15557595058 15557595058 · [email protected]
武汉鑫儒化工有限公司15927387915 15337108568 · [email protected]
安耐吉化学&3A(安徽泽升科技股份有限公司)400-0056266 · [email protected]
Shijiazhuang Erche Biotechnology Co., Ltd8613343119830 13343119830 · [email protected]
湖北辰心化工有限公司17362916295 · [email protected]
艾吉析科技(上海)有限公司17717235263 17717235263 · [email protected]
추가 설명 · 1건

정의ChEBI: Trenbolone is a 3-oxo-Delta(4) steroid that is estra-4,9,11-triene carrying an oxo group at position 3 and a hydroxy group at position 17beta. It is a synthetic anabolic steroid used for muscle growth in livestock. It has a role as a plant metabolite and an endocrine disruptor. It is a 3-oxo-Delta(4) steroid, a 17beta-hydroxy steroid, a C18-steroid and an anabolic androgenic steroid.

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