기본 정보
- CAS
15763-06-1- 표준 SMILES
Cn1cnc2c(ncn2C2OC(CO)C(O)C2O)c1=N- InChIKey
GFYLSDSUCHVORB-UHFFFAOYSA-N- 분자식
- C11H15N5O4
- 평균 분자량
- 281.27 g/mol
- 단동위원소 질량
- 281.11240398
개요
See also: 1-Methyladenosine (annotation moved to).
이름 및 식별자
- 우선 이름
- N1-Methyladenosine
- IUPAC
- 2-(hydroxymethyl)-5-(6-imino-1-methylpurin-9-yl)oxolane-3,4-diol
- 현지명
- 1-메틸라데노신
- 영어명
- 1-Methyladenosine
- 분자식
- C11H15N5O4
- 분자량
- 281.27
이름 및 동의어
1-methyl adenosineN1-Methyladenosine1-methyladenosin2-(hydroxymethyl)-5-(6-imino-1-methylhydropurin-9-yl)oxolane-3,4-diolAdenosine, 1-methyl-MFCD00038421(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-imino-1-methyl-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diol;2-(hydroxymethyl)-5-(6-imino-1-methylpurin-9-yl)oxolane-3,4-diolCHEMBL5498528SCHEMBL23666509NSC92165NSC-92165
이름 더 보기
1-메틸라데노신N1-Me-rAN1-Me-Adenosine1-Methyladenosine1-methyladenosine free baseRNA-modified nucleoside m1A1-Methyladenosine, 10 mM in DMSO(2R,3R,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-purin-9-yl)oxolane-3,4-diolinhibit,1-Methyladenosine,1 Methyladenosine,Endogenous Metabolite,Inhibitor,1Methyladenosine
AKOS024282333PD045893ST055626NS00014644Adenosine,6-didehydro-1,6-dihydro-1-methyl-N,6-DIDEHYDRO-1,6-DIHYDRO-1-METHYLADENOSINE2-(hydroxymethyl)-5-(6-imino-1-methyl-purin-9-yl)tetrahydrofuran-3,4-diol
물성
구조 계산 물성
- XLogP
- -1
- 극성 표면적
- 127 Ų
- 수소 결합 공여자 수
- 4
- 수소 결합 수용자 수
- 7
- 회전 가능 결합 수
- 2
- 무거운 원자 수
- 20
- 형식 전하
- 0
- 복잡도
- 433
물리화학적 성질
- 녹는점
- 217 °C · >217°C (dec.)
- 끓는 점
- 655.4 · 655.4±65.0 °C(Predicted)
- 밀도
- 1.88 · 1.88±0.1 g/cm3(Predicted)
- 저장 조건
- 20 °C · −20°C
- 용해도
- DMSO (약간 용해됨), 물 (약간 용해됨,초음파처리)
- 물리적 상태
- 고체
- 산도 계수 (pKa)
- 13.24 · 13.24±0.70(Predicted)
- 색상
- 흰색에서 황백색까지
- 수소이온지수(pH)
- 8.8 · 8.8
- 안정성
- 흡습성, 감광성
- InChI
- InChI=1/C11H15N5O4/c1-15-3-14-10-6(9(15)12)13-4-16(10)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11-12,17-19H,2H2,1H3/t5-,7-,8-,11-/s3
- InChIKey
- GFYLSDSUCHVORB-ABFAXUGDNA-N
- SMILES
- N1(C=NC2C(=N)N(C)C=NC1=2)[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 |&1:11,12,14,16,r|
화학적 성질
White to off-white crystalline powder
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- wgk
- WGK 3
- HS 번호
- 29389090
- safety_code
- 24/25
- 스토리지 클래스
- 11 - Combustible Solids
화학 및 산업
응용 분야
개요1-Methyladenosine is a modified nucleoside generated by the processing of tRNA by methyltransferases. The urinary excretion of 1-methyladenosine is elevated in several forms of cancer, supporting its use as a biomarker in early detection. It can also be monitored in serum. Urinary levels of 1-methyladenosine also increase during active rheumatoid arthritis.
용도1-Methyl Adenosine is a modified adenosine molecule created through the processing of tRNA by methyltransferases. The presence seen to be elevated in the urinary excretion of cancer patients. Thus it may be an early diagnosis biomarker.
공급사79 곳
Zhengzhou Chemprize Biotech Co., Ltd.+86-86-0371-56768238 +86-15981919713 · [email protected]
湖南韵邦生物科技股份有限公司0731-88532326 13319508186 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
上海遐瑞医药科技有限公司+86-021-61551413 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]
攀纳燊（河南）医药科学技术有限公司0371-65325800 13700860222 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
관련 반응
0건
현재 필터 조건에 해당하는 반응 기록이 없습니다.
화합물 노트
불러오는 중…