폭심

Phoxim

HCID 26927CAS 14816-18-3

기본 정보

표준 SMILES
CCOP(=S)(OCC)ON=C(C#N)c1ccccc1
InChIKey
ATROHALUCMTWTB-UHFFFAOYSA-N
분자식
C12H15N2O3PS
평균 분자량
298.3 g/mol
단동위원소 질량
298.05410052

이름 및 식별자

우선 이름
Phoxim
IUPAC
N-diethoxyphosphinothioyloxybenzenecarboximidoyl cyanide
현지명
폭심
영어명
Phoxim
분자식
C12H15N2O3PS
분자량
298.3

이름 및 동의어

PHOXIM14816-18-3BaythionPhoximeSebacil (insecticide)6F5V775VPOBAYER-9053Bay-77488BAY 77488PhoxinDTXSID8034324Phenylglyoxylnitrile oxime O,O-diethyl phosphorothioate
이름 더 보기
폭심폭심(PHOXIM)Foximb77488VOLATONoms1170Sebacilsra7502Valexon
O,O-Diethyl-alpha-cyanobenzylidineaminooxyphosphonothiateCHEBI:38812Sebacil Pour-onRefChem:863020DTXCID20810007phenylglyoxylonitrile oxime O,O-diethylphosphorothioate238-887-3alpha-(((Diethoxyphosphinothioyl)oxy)imino)benzeneacetonitrile

데이터베이스 식별자

CAS
14816-18-3
PubChem CID
26927
DTXSID
DTXSID8034324
ChEMBL
CHEMBL1906626
UNII
6F5V775VPO
EC Number
238-887-3

물성

구조 계산 물성

XLogP
4.4
극성 표면적
95.9 Ų
수소 결합 공여자 수
0
수소 결합 수용자 수
6
회전 가능 결합 수
7
무거운 원자 수
19

실험 및 물리화학적 성질

Collision Cross Section165.7 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID8034324]

물리화학적 성질

녹는점
5.55 °C · 5.55°C
끓는 점
0.01 · bp0.01 102°
밀도
420 · d420 1.176
증기압
2.1 · 2.1×10-3 Pa (20 °C)
굴절률
20 · nD20 1.5405
저장 조건
0 · 0-6°C

화학적 성질

yellowish oily liquid, Specific gravity: 1.176 (20°C)

안전 및 규제

GHS 분류

GHS Classification · 6건

Warning

H302: Harmful if swallowed [Warning Acute toxicity, oral];H317: May cause an allergic skin reaction [Warning Sensitization, Skin];H361f ***: Suspected of damaging fertility [Warning Reproductive toxicity];H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard];H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P203, P261, P264, P270, P272, P273, P280, P301+P317, P302+P352, P318, P321, P330, P333+P317, P362+P364, P391, P405, and P501 (click each P-code to see the statement)

Danger

유해성 정보

Other Safety Information · 1건

IMAP assessments - 3,5-Dioxa-6-aza-4-phosphaoct-6-ene-8-nitrile, 4-ethoxy-7-phenyl-, 4-sulfide: Human health tier I assessment;IMAP assessments - 3,5-Dioxa-6-aza-4-phosphaoct-6-ene-8-nitrile, 4-ethoxy-7-phenyl-, 4-sulfide: Environment tier I assessment

Hazard Classes and Categories · 3건

Acute Tox. 3 (33.6%);Acute Tox. 4 (66.4%);Acute Tox. 3 (67.3%);Skin Sens. 1 (97.3%);Acute Tox. 2 (34.5%);Repr. 2 (96.5%);Aquatic Acute 1 (100%);Aquatic Chronic 1 (100%)

Reproductive toxicity - category 2;Acute toxicity - category 4;Skin sensitisation - category 1;Hazardous to the aquatic environment (acute) - category 1;Hazardous to the aquatic environment (chronic) - category 1

Repr. 2;Acute Tox. 4 *;Skin Sens. 1;Aquatic Acute 1;Aquatic Chronic 1

독성 정보

Acute Toxicity LinkChemical: PHOXIM

안전 데이터

wgk
3
rtecs
MD4740000
ridadr
UN 2810
독성
LD50 orally in mice: >2000 mg/kg (Vinopal, Fukuto)
HS 번호
29269090
risk_code
22-50/53-62-43

화학 및 산업

약리 정보

ATC CodeQP - Antiparasitic products, insecticides and repellents;QP53 - Ectoparasiticides, insecticides and repellents;QP53A - Ectoparasiticides for topical use, incl. insecticides;QP53AF - Organophosphorous compounds;QP53AF01 - Phoxime
MeSH Pharmacological Classification · 2건

Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.

Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.

용도 및 제조

Use Classification · 4건

Veterinary Drug -> INSECTICIDE -> JECFA Functional Classes

Veterinary Drug -> INSECTICIDE -> JECFA Functional Classes

Veterinary Drug -> INSECTICIDE -> JECFA Functional Classes

INSECTICIDES

응용 분야 · 2건

개요Phoxim is a light yellow liquid, Solubility in water is 1.5 mg/L (20 C). It is readily soluble in most organic solvents and slightly in aliphatic hydrocarbons. Log Kow = 3.38. It is relatively slowly hydrolyzed in aqueous media; DT50 (22 C) at pH 4, 7, and 9 is 26.7, 7.2, and 3.1 d, respectively.

용도Phoxim is used to control stored product insect pests in silos and barns. It is also used to control household insects such as ants and other public health pests. Agricultural targets include caterpillars and soil insects in maize, vegetables, cotton and potatoes.

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖北万得化工有限公司15377098680 15377098680 · [email protected]
湖北威德利化学试剂有限公司181-6332-1995 18062128043 · [email protected]
盐城通铭生物科技有限公司15195160625 · [email protected]

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