기본 정보
- 표준 SMILES
CCOP(=S)(OCC)ON=C(C#N)c1ccccc1- InChIKey
ATROHALUCMTWTB-UHFFFAOYSA-N- 분자식
- C12H15N2O3PS
- 평균 분자량
- 298.3 g/mol
- 단동위원소 질량
- 298.05410052
이름 및 식별자
- 우선 이름
- Phoxim
- IUPAC
- N-diethoxyphosphinothioyloxybenzenecarboximidoyl cyanide
- 현지명
- 폭심
- 영어명
- Phoxim
- 분자식
- C12H15N2O3PS
- 분자량
- 298.3
이름 및 동의어
이름 더 보기
데이터베이스 식별자
- CAS
14816-18-3- PubChem CID
- 26927
- DTXSID
DTXSID8034324- ChEMBL
CHEMBL1906626- UNII
- 6F5V775VPO
- EC Number
- 238-887-3
물성
구조 계산 물성
- XLogP
- 4.4
- 극성 표면적
- 95.9 Ų
- 수소 결합 공여자 수
- 0
- 수소 결합 수용자 수
- 6
- 회전 가능 결합 수
- 7
- 무거운 원자 수
- 19
- 형식 전하
- 0
- 복잡도
- 389
실험 및 물리화학적 성질
물리화학적 성질
- 녹는점
- 5.55 °C · 5.55°C
- 끓는 점
- 0.01 · bp0.01 102°
- 밀도
- 420 · d420 1.176
- 증기압
- 2.1 · 2.1×10-3 Pa (20 °C)
- 굴절률
- 20 · nD20 1.5405
- 저장 조건
- 0 · 0-6°C
- 용해도
- 아세토니트릴(약간 용해됨), 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 수용성
- 1.5 mg · 1.5mg l-1(20°C)
- 물리적 상태
- 액체
- 색상
- Colorless to light yellow
- Henry's Law Constant
- 5 · 5.0×101 mol/(m3Pa) at 25℃, Ebert et al. (2023)
- 안정성
- 흡습성, 수분 민감성
- InChIKey
- ATROHALUCMTWTB-WYMLVPIESA-N
- NIST
- Phoxim(14816-18-3)
- EPA
- Phoxim (14816-18-3)
화학적 성질
yellowish oily liquid, Specific gravity: 1.176 (20°C)
안전 및 규제
GHS 분류
GHS Classification
Warning
H302: Harmful if swallowed [Warning Acute toxicity, oral];H317: May cause an allergic skin reaction [Warning Sensitization, Skin];H361f ***: Suspected of damaging fertility [Warning Reproductive toxicity];H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard];H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
P203, P261, P264, P270, P272, P273, P280, P301+P317, P302+P352, P318, P321, P330, P333+P317, P362+P364, P391, P405, and P501 (click each P-code to see the statement)
Danger
유해성 정보
Other Safety Information
IMAP assessments - 3,5-Dioxa-6-aza-4-phosphaoct-6-ene-8-nitrile, 4-ethoxy-7-phenyl-, 4-sulfide: Human health tier I assessment;IMAP assessments - 3,5-Dioxa-6-aza-4-phosphaoct-6-ene-8-nitrile, 4-ethoxy-7-phenyl-, 4-sulfide: Environment tier I assessment
Hazard Classes and Categories
Acute Tox. 3 (33.6%);Acute Tox. 4 (66.4%);Acute Tox. 3 (67.3%);Skin Sens. 1 (97.3%);Acute Tox. 2 (34.5%);Repr. 2 (96.5%);Aquatic Acute 1 (100%);Aquatic Chronic 1 (100%)
Reproductive toxicity - category 2;Acute toxicity - category 4;Skin sensitisation - category 1;Hazardous to the aquatic environment (acute) - category 1;Hazardous to the aquatic environment (chronic) - category 1
Repr. 2;Acute Tox. 4 *;Skin Sens. 1;Aquatic Acute 1;Aquatic Chronic 1
독성 정보
안전 데이터
- wgk
- 3
- rtecs
- MD4740000
- ridadr
- UN 2810
- 독성
- LD50 orally in mice: >2000 mg/kg (Vinopal, Fukuto)
- HS 번호
- 29269090
- risk_code
- 22-50/53-62-43
- hazard_code
- Xn;N,N,Xn
- safety_code
- 36-60-61-46-36/37
- 포장분류
- III
- 위험 등급
- 6.1(b)
- 기존화학 물질
- KE-13465
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.
용도 및 제조
Use Classification
Veterinary Drug -> INSECTICIDE -> JECFA Functional Classes
Veterinary Drug -> INSECTICIDE -> JECFA Functional Classes
Veterinary Drug -> INSECTICIDE -> JECFA Functional Classes
INSECTICIDES
응용 분야
개요Phoxim is a light yellow liquid, Solubility in water is 1.5 mg/L (20 C). It is readily soluble in most organic solvents and slightly in aliphatic hydrocarbons. Log Kow = 3.38. It is relatively slowly hydrolyzed in aqueous media; DT50 (22 C) at pH 4, 7, and 9 is 26.7, 7.2, and 3.1 d, respectively.
용도Phoxim is used to control stored product insect pests in silos and barns. It is also used to control household insects such as ants and other public health pests. Agricultural targets include caterpillars and soil insects in maize, vegetables, cotton and potatoes.
상·하류 제품 정보
상류 원료
하류 제품
공급사50 곳
관련 반응
연결된 노트
불러오는 중…