| GHS 분류 | DangerH301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]P203, P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 48 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity] |
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| 건강 유해성 | SYMPTOMS: Symptoms of exposure to this compound include leukemia, dyspnea, cough, interstitial fibrosis and menstrual cycle changes or disorders. It may cause keratitis epithelialis in association with exfoliative dermatitis and reversible pseudotumor cerebri with papilledema. It may also cause vomiting, lethargy and unconsciousness with grand mal seizures. Other symptoms include convulsions, infertility, reversible and permanent sterility, lymphopenia, neutropenia, bone marrow suppression, gastrointestinal disturbances such as nausea, diarrhea and oral ulceration, hepatotoxicity, jaundice, drug fever, skin hypersensitivity, peripheral neuropathy, sterile cystitis, fibrosis, vasculitis and depletion of primordial follicles, skin rash, bleeding, unusual lumps, agitated behavior and ataxia. It may cause hyperuricemia, which may lead to acute renal failure, reversible pancytopenia, sideroblastic anemia and myeloblastic leukemia. Exposure may cause erythroleukemia, reticulum-cell sarcoma, lymphosarcoma, myelosuppression, viral, fungal and bacterial infections, chromosomal damage and oligospermia, azoospermia and disappearance of testicular germinal cells in males. It may cause irreversible bone marrow depression, central nervous excitation and jerky movements. It may also cause thrombocytopenia, leucopenia and hemorrhage of the skin and mucous membranes. Other symptoms of exposure include coma, irritation to the skin and mucous membranes, lymphocytopenia, cutaneous pigmentation, adrenal cortical insufficiency and neurotoxicity. It may cause amenorrhea and dermatitis. When administered to a pregnant woman, the offspring may develop unilateral renal agenesis. It may be injurious to the developing retina. |
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