4-(2-하이드록시에틸)피페라진-1-에탄설포닉 산, 나트륨 염 (1:1)

Sodium 2-(4-(2-hydroxyethyl)piperazin-1-yl)ethanesulfonate

HCID 2724248

기본 정보

CAS
75277-39-3
표준 SMILES
O=S(=O)([O-])CCN1CCN(CCO)CC1.[Na+]
InChIKey
RDZTWEVXRGYCFV-UHFFFAOYSA-M
분자식
C8H17N2NaO4S
평균 분자량
260.29 g/mol
단동위원소 질량
260.08067248

이름 및 식별자

우선 이름
Sodium 2-(4-(2-hydroxyethyl)piperazin-1-yl)ethanesulfonate
IUPAC
sodium 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonate
현지명
4-(2-하이드록시에틸)피페라진-1-에탄설포닉 산, 나트륨 염 (1:1)
영어명
HEPES sodium salt
분자식
C8H19N2NaO4S
분자량
261.3

이름 및 동의어

75277-39-3Sodium 2-(4-(2-hydroxyethyl)piperazin-1-yl)ethanesulfonate103404-87-1sodium 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonateHEPES (sodium)4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid hemisodium saltZ9FTO91O8A1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, monosodium saltUNII-Z9FTO91O8AC8H17N2NaO4SMFCD00036463hepes sodium
이름 더 보기
4-(2-하이드록시에틸)피페라진-1-에탄설포닉산,나트륨염(1:1)헤페스나트륨염HEPES NAHEPES SODIUM SALT BUFFERHEPES, SODIUMH7006-500G(HEPES)2-NAHEPES NA-SALTRUTHENIUM STANDHEPES LOWSODIUMHEPES SODIUM SALT1.0 M HEPES sodium
4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid sodium saltDTXSID4044458Sodium 4-(2-hydroxyethyl)piperazin-1-ylethanesulphonatesodium;2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonateEINECS 278-169-71-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, sodium salt (1:1)AKOS015897769FT-0610868

데이터베이스 식별자

CAS
75277-39-3
PubChem CID
2724248
DTXSID
DTXSID4044458
ChEMBL
CHEMBL3187284
ChEBI
CHEBI:46758
UNII
Z9FTO91O8A
EC Number
278-169-7
Nikkaji
J307.551F

물성

구조 계산 물성

극성 표면적
92.3 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
6
회전 가능 결합 수
5
무거운 원자 수
16

실험 및 물리화학적 성질

Physical Description · 2건

Dry Powder

White powder; [Sigma-Aldrich MSDS]

물리화학적 성질

녹는점
234 °C · 234 °C
밀도
1.504 · 1.504[at 20℃]
증기압
0 Pa · 0Pa at 25℃
저장 조건
room temp
용해도
2 O: · H2O: 1 M at 20 °C, 투명, 무색
물리적 상태
건조 분말

화학적 성질

white powder

안전 및 규제

GHS 분류

GHS Classification · 3건

This chemical does not meet GHS hazard criteria for 98.8% (160 of 162) of all reports.

Not Classified;Reported as not meeting GHS hazard criteria by 160 of 162 companies (only 1.2% companies provided GHS information). For more detailed information, please visit ECHA C&L website.

Aggregated GHS information provided per 162 reports by companies from 3 notifications to the ECHA C&L Inventory.;Reported as not meeting GHS hazard criteria per 160 of 162 reports by companies.;There is 1 notification provided by 2 of 162 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 5건

Chemical: 1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, monosodium salt

1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, sodium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, sodium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Status: Active Update: 08-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/21261

1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, monosodium salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazards SummaryMay cause irritation; [Sigma-Aldrich MSDS] See Piperazine and salts. See HEPES.
Hazard Classes and CategoriesNot Classified

규제 정보

Regulatory Information · 5건

Chemical: 1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, monosodium salt

1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, sodium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, sodium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Status: Active Update: 08-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/21261

1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, monosodium salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

안전 데이터

wgk
3
tsca
TSCA listed
HS 번호
29335995
safety_code
22-24/25
F 고인화성물질
3-10
스토리지 클래스
13 - Non Combustible Solids

화학 및 산업

용도 및 제조

UsesA dipolar ionic buffer. [ChemIDplus]
U.S. Production2023: 28,556 lb
Consumer UsesStabilizing agent
Industry UsesStabilizing agent
General Manufacturing Information · 2건

Pharmaceutical and Medicine Manufacturing

1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, sodium salt (1:1): ACTIVE

응용 분야 · 2건

용도HEPES sodium salt solution is suitable for cell culture studies. It may be used in the preparation of buffer solution of HEPES. It may be used as buffer during the phosphorylation assays in permeabilized fibroblasts. It may be used to compose a complex dialysis buffer, used in the determination of free thyroxin in serum by radioimmunoassay.

일반 설명HEPES is a general-purpose zwitterionic buffer which does not bind magnesium, calcium, manganese(II) or copper(II) ions. HEPES has been classified as Good′s buffer by Dr. Norman Good and his colleagues in 1966. It is zwitterionic at biological pH and is most effective in the pH range of 6.8 to 8.2.

공급사100 곳

北京华美互利生物化工010-56205725 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
河北创海生物科技有限公司+86-86-13131129325 · [email protected]
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
上海如吉生物科技发展有限公司+86-21-65211385-8001 36031160 · [email protected]

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