기본 정보
- CAS
74389-69-8- 표준 SMILES
CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(C)=O- InChIKey
ZXCIEWBDUAPBJF-MUUNZHRXSA-N- 분자식
- C28H58NO7P
- 평균 분자량
- 551.7 g/mol
- 단동위원소 질량
- 551.39509019
개요
2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine is a 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has octadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis. It has a role as a beta-adrenergic antagonist, a vasodilator agent, an antihypertensive agent, a bronchoconstrictor agent and a hematologic agent.
이름 및 식별자
- 우선 이름
- 1-O-octadecyl-platelet-activating factor
- IUPAC
- [(2R)-2-acetyloxy-3-octadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
- 영어명
- PAF (C18)
- 분자식
- C28H58NO7P
- 분자량
- 551.74
이름 및 동의어
74389-69-81-O-Octadecyl-platelet-activating factorRefChem:1056128C18-Paf-acetherPlatelet activating factor-acetherC18-PAFPAF (C18)PAF C-181-O-Octadecyl-2-acetyl-sn-glycero-3-phosphocholine1-O-Octadecyl-2-O-acetyl-sn-glycero-3-phosphocholineRo 14-81611-O-Octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine
이름 더 보기
C18 PAFro14-8161C18-02:0 PCPAF (C18),99%PLATELET ACTIVATING FACTOR-18PLATELET ACTIVATING FACTOR (C18)hydroxide,innersalt,4-oxide,(r)-thyl1-O-STEARYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
1-O-Stearoyl-2-acetyl-sn-glyceryl-3-phosphorylcholine1-octadecyl-2-acetyl-sn-glycero-3-phosphocholine1-O-octadecyl-PAF[(2R)-2-acetyloxy-3-octadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphatePC(O-18:0/2:0)C18:0 PAFMFCD00063528phosphatidylcholine (O-18:0/2:0)
데이터베이스 식별자
- CAS
물성
구조 계산 물성
- XLogP
- 7.6
- 극성 표면적
- 94.1 Ų
- 수소 결합 공여자 수
- 0
- 수소 결합 수용자 수
- 7
- 회전 가능 결합 수
- 28
- 무거운 원자 수
- 37
- 형식 전하
- 0
- 복잡도
- 575
실험 및 물리화학적 성질
LipidsLipids -> Glycerophospholipids [GP] -> Glycerophosphocholines [GP01] -> 1-alkyl,2-acylglycerophosphocholines [GP0102]
물리화학적 성질
- 저장 조건
- -20 °C · -20°C
- 용해도
- 10 mg/mL · 클로로포름: 10 mg/mL
- 물리적 상태
- powder
- 색상
- White to off-white
- InChI
- 1S/C28H58NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-33-25-28(36-27(2)30)26-35-37(31,32)34-24-22-29(3,4)5/h28H,6-26H2,1-5H3/t28-/m1/s1
- InChIKey
- ZXCIEWBDUAPBJF-MUUNZHRXSA-N
- SMILES
- [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C)=O)COCCCCCCCCCCCCCCCCCC)=O
화학적 성질
white solid
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- wgk
- 3
- HS 번호
- 29310099
- safety_code
- 24/25
- 스토리지 클래스
- 11 - Combustible Solids
화학 및 산업
응용 분야
용도C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine is suitable as a substrate for enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay.
일반 설명C18-02:0 PC, also known as 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine (C18∶0-PAF), is a platelet-activating factor lipid. It belongs to a class of natural PAFs and is produced in basophil leucocytes, macrophages, polymorphonuclear neutrophils and monocytes and platelets.
상·하류 제품 정보
상류 원료
공급사24 곳
阿诺西（上海）生物技术有限公司400-1107768 15058188853 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
赛默飞世尔科技（中国）有限公司
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