(R)-(-)-1-메톡시-2-프로판올

(R)-(-)-1-Methoxy-2-propanol

HCID 2733589

노트 반응

부분 구조 검색 유사 구조 찾기

기본 정보

CAS: 4984-22-9
표준 SMILES: COC[C@@H](C)O
InChIKey: ARXJGSRGQADJSQ-SCSAIBSYSA-N
분자식: C4H10O2
평균 분자량: 90.12 g/mol

이름 및 식별자

우선 이름: (R)-(-)-1-Methoxy-2-propanol
IUPAC: (2R)-1-methoxypropan-2-ol
현지명: (R)-(-)-1-메톡시-2-프로판올
영어명: (R)-(-)-1-Methoxy-2-propanol
분자식: C4H10O2
분자량: 90.12

이름 및 동의어

(R)-(-)-1-Methoxy-2-propanol4984-22-9RefChem:407029628-460-3(2R)-1-methoxypropan-2-ol(r)-1-methoxy-2-propanol(R)-1-methoxypropan-2-olMFCD016325872-Propanol, 1-methoxy-, (2R)-R-(-)-1-Methoxy-2-propanol(R)-1-methoxy-propan-2-ol(R)-methoxy-propan-2-ol

이름 더 보기

(R)-(-)-1-메톡시-2-프로판올2-Propanol, 1-Methoxy-,(2R)-(R)-(-)-1-Methoxypropan-2-ol(R)-1-METHOXY-2-PROPANOL,95+%(R)-2-HYDROXY-1-METHOXYPROPANE(R)-(-)-1-Methoxy-2-propanol>(R)-(-)-1-METHOXY-2-PROPANOL 98%(R)-(-)-1-Methoxy-2-propanol, 98+%

(R)-(-)-Propylene Glycol 1-Monomethyl EtherSCHEMBL76862(2R)-1-methoxypropane-2-olSCHEMBL2394984SCHEMBL18187191(2R)-2-hydroxy-1-methoxypropane(r)-(-)-1-methoxy-propan-2-olAKOS006341650

데이터베이스 식별자

CAS: 4984-22-9
PubChem CID: 2733589
EC Number: 628-460-3
Nikkaji: J1.533.245J

물성

구조 계산 물성

XLogP: -0.2
극성 표면적: 29.5 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 2
회전 가능 결합 수: 2
무거운 원자 수: 6
형식 전하: 0
복잡도: 28.7

물리화학적 성질

녹는점: -97 °C · -97 °C
끓는 점: 119 · 119-121 °C (lit.)
밀도: 0.921 g/mL · 0.921 g/mL at 20 °C (lit.)
굴절률: 20 · n20/D 1.403
인화점: 33 °C · 33 °C
저장 조건: 2 · Sealed in dry,2-8°C
물리적 상태: 액체
산도 계수 (pKa): 14.49 · 14.49±0.20(Predicted)
색상: 무색의
BRN: 1718941 · 1718941
InChI: InChI=1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3/t4-/m1/s1
InChIKey: ARXJGSRGQADJSQ-SCSAIBSYSA-N
SMILES: C(OC)[C@H](O)C

화학적 성질

Colorless to light yellow liqui

안전 및 규제

GHS 분류

GHS Classification · 4건

Warning

H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 42 reports by companies from 4 notifications to the ECHA C&L Inventory.

유해성 정보

Hazard Classes and CategoriesFlam. Liq. 3 (100%)

안전 데이터

wgk: 1
ridadr: UN 3092 3/PG 3
HS 번호: 29051990
risk_code: 10-15
hazard_code: F,Xn
safety_code: 24-43-7/8
포장분류: Ⅲ
위험 등급: 3
Hazard Classifications: Flam. Liq. 3
스토리지 클래스: 3 - Flammable liquids

화학 및 산업

응용 분야 · 2건

용도(R)-(-)-1-Methoxy-2-propanol can be used as a reactant to prepare: (S)-3-(ethoxycarbonyl)-5-((1-methoxypropan-2-yl)oxy)benzoic acid, a key intermediate to synthesize phenylethyl benzamide derivatives, which can be used as glucokinase activators. Chiral pyrazolopyrimidinone derivatives as potential phosphodiesterase enzyme (PDE5) inhibitors. Aryl or alkyl ethers via etherification reaction.

일반 설명(R)-(-)-1-Methoxy-2-propanol is a chiral secondary alcohol. It is formed during the hydrolysis of (R)-1-methoxy-2-propyl-acetate in the presence of Candida antarctica lipase B.