기본 정보
- CAS
2576-47-8- 표준 SMILES
Br.NCCBr- InChIKey
WJAXXWSZNSFVNG-UHFFFAOYSA-N- 분자식
- C2H6BrN.BrH
- 평균 분자량
- 204.89 g/mol
- 단동위원소 질량
- 202.89452342
개요
Crystals. (NTP, 1992)
이름 및 식별자
- 우선 이름
- 2-Bromoethylamine hydrobromide
- IUPAC
- 2-bromoethanamine;hydrobromide
- 현지명
- 2-브로모에틸아민 브롬화수소산염
- 영어명
- 2-Bromoethylamine hydrobromide
- 분자식
- C2H7Br2N
- 분자량
- 204.89
이름 및 동의어
2-Bromoethylamine hydrobromide2576-47-82-Bromoethanamine hydrobromide2-Bromoethylammonium bromide2-Aminoethyl bromide hydrobromideEthanamine, 2-bromo-, hydrobromide2-Aminoethylbromide hydrobromidebeta-Bromoethylamine hydrobromideEthanamine, 2-bromo-, hydrobromide (1:1)FQL7XH8MAFNSC-3379NSC-3406
이름 더 보기
2-브로모에틸아민브롬화수소산염2BEHRJACS-2576-47-8BromoethylamineHbr2-Bromoethanamine HBrAMINOETHYL BROMIDE HBR2-BROMOETHYLAMINE HBR 99%2-(DIALLYLAMINO)ETHYLAMINE2-Bromoethylazanium bromidebromoethylamine,hydrobromide
DTXSID30883868ETHYLAMINE, 2-BROMO-, HYDROBROMIDERefChem:85873bromoethyleneamine hydrobromideDTXCID401023350219-924-22-Bromoethylamine HBrMFCD00012886
데이터베이스 식별자
- CAS
2576-47-8- PubChem CID
물성
구조 계산 물성
- 극성 표면적
- 26 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 1
- 회전 가능 결합 수
- 1
- 무거운 원자 수
- 5
- 형식 전하
- 0
- 복잡도
- 10
실험 및 물리화학적 성질
Chemical ClassesNitrogen Compounds -> Amines, Aliphatic
SolubilitySoluble (NTP, 1992)
Melting Point342 to 345 °F (NTP, 1992)
Physical Description
Crystals. (NTP, 1992)
Solid; [CAMEO] White crystalline powder; [Alfa Aesar MSDS]
물리화학적 성질
- 녹는점
- 172 °C · 172 °C
- 끓는 점
- 181.3 ℃[at · 181.3℃[at 101 325 Pa]
- 밀도
- 1.9061 · 1.9061 (rough estimate)
- 증기압
- 0.001 Pa · 0.001Pa at 25℃
- 굴절률
- 1.5393 · 1.5393 (estimate)
- 저장 조건
- 30 °C · Store below +30°C.
- 용해도
- 500 g/L · >500g/L
- 물리적 상태
- 결정질 분말 또는 결정
- 색상
- 흰색~밝은 베이지
- 수소이온지수(pH)
- 2.9 · 2.9 (10g/l, H2O, 20℃)
- 수용성
- 500 g/L · > 500g/L(20℃)
- BRN
- 3607605 · 3607605
안전 및 규제
GHS 분류
GHS Classification
Warning
H302 (39.7%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 73 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Regulatory Information
Chemical: Ethanamine, 2-bromo-, hydrobromide
Status: Active Update: 15-11-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/19393
2-Bromoethylammonium bromide: Does not have an individual approval but may be used under an appropriate group standard
Fire HazardsFlash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Health HazardsACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits very toxic fumes of bromide ion, NOx and hydrogen bromide. (NTP, 1992)
Hazards SummaryCauses changes in kidney and bladder in acute intraperitoneal toxic-dose studies of rats; [RTECS] A skin and strong eye irritant; May cause skin sensitization; Harmful by ingestion; [Alfa Aesar MSDS] See 2-Bromoethylamine.
Reactive GroupHalogenated Organic Compounds
Reactivity Profile
The acidic organic salt (HBr) of the amine. Acidic salts are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.
화학 및 산업
용도 및 제조
General Manufacturing InformationEthanamine, 2-bromo-, hydrobromide (1:1): ACTIVE
응용 분야
용도2-Bromoethylamine hydrobromide is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone. It acts as a building block which is used for proteomics research. It is also used as organic and pharmaceutical intermediates for the preparation of first-aid medicines.
일반 설명Crystals.
제조 방법
2-Bromoethylamine hydrobromide was synthesized by bromination of ethanolamine. Drop into hydrobromic acid in the reaction pot, cool, add ethanolamine dropwise under stirring, and finish adding dropwise within half an hour, then steam the hydrobromic acid of 85% of the input quantity (the feed quantity of hydrobromic acid is 8.89 times the weight of ethanolamine) , about 20h steamed. After the concentrated solution is cooled to 70-80°C, it is put into pre-chilled acetone, cooled to below 5°C, and the crystallized 2-bromoethylamine hydrobromide is filtered out. Yield 70%.
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