Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
시클로펜틸아민
사이크로펜틸아민 · 시클로펜틸아민 · 싸이크로펜틸아민 · 사이클로펜틸아민 · Cyclopentanamine · Cyclopentylamine,Aminocyclopentane · cb1689 · Ring aMylaMine
식별자 및 물리적 특성
| CAS No. | 1003-03-8 |
|---|---|
| 분자식 | C5H11N |
| 평균 분자량 | 85.15 g/mol |
| 단동위원소 질량 | 85.08914936 g/mol |
| SMILES | NC1CCCC1 |
| InChIKey | NISGSNTVMOOSJQ-UHFFFAOYSA-N |
| PubChem CID | 2906 |
| ChEMBL | CHEMBL1171859 |
| EC No. | 213-697-3 |
| DTXSID | DTXSID4061387 |
| 현지명 | 시클로펜틸아민 |
화학 및 물리적 성질
| XLogP | 0.6 |
|---|---|
| 극성 표면적 | 26 |
| 수소 결합 공여자 수 | 1 |
| 수소 결합 수용자 수 | 1 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 6 |
| 형식 전하 | 0 |
| 복잡도 | 37 |
| 녹는점 | -85°C |
| 끓는 점 | 106-108 °C(lit.) |
| 밀도 | 0.863 g/mL at 25 °C(lit.) |
| 증기압 | 26.72hPa at 20℃ |
| 굴절률 | n20/D 1.450(lit.) |
| 인화점 | 63 °F |
| 저장 조건 | Flammables area |
| 물리적 상태 | 액체 |
| pKa(산도 계수) | pK1:10.65(+1) (25°C) |
| 색상 | 투명한 |
| 폭발한계 | 1.3-9.40%(V) |
| 용해도 | 혼용 가능 |
| 비열 | Cp(liquid): 2.13 J/(g·K), at 25℃ |
| BRN | 635706 |
| InChI | 1S/C5H11N/c6-5-3-1-2-4-5/h5H,1-4,6H2 |
| InChIKey | NISGSNTVMOOSJQ-UHFFFAOYSA-N |
| SMILES | NC1CCCC1 |
| LogP(분배 계수) | 0.83 at 20℃ |
| NIST | Cyclopentanamine(1003-03-8) |
| EPA | Cyclopentanamine (1003-03-8) |
화학적 성질
a colorless liquid with an ammoniacal odor.
안전 및 규제
| GHS 분류 | This chemical does not meet GHS hazard criteria for 0.6% (1 of 154) of reports.DangerH225 (99.4%): Highly Flammable liquid and vapor [Danger Flammable liquids]H300 (97.4%): Fatal if swallowed [Danger Acute toxicity, oral]H314 (74.7%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]H315 (25.3%): Causes skin irritation [Warning Skin corrosion/irritation]H317 (31.2%): May cause an allergic skin reaction [Warning Sensitization, Skin]H318 (94.2%): Causes serious eye damage [Danger Serious eye damage/eye irritation]H331 (69.5%): Toxic if inhaled [Danger Acute toxicity, inhalation]H332 (26.6%): Harmful if inhaled [Warning Acute toxicity, inhalation]H412 (68.8%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P332+P317, P333+P317, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 154 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Reported as not meeting GHS hazard criteria per 1 of 154 reports by companies.There are 9 notifications provided by 153 of 154 reports by companies with hazard statement code(s).Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| 규제 정보 | Status: Active Update: 28-08-2013 https://echa.europa.eu/registration-dossier/-/registered-dossier/7046Status: Active Update: 29-01-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/10145Cyclopentylamine: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Flam. Liq. 2 (99.4%)Acute Tox. 2 (97.4%)Skin Corr. 1B (74.7%)Skin Irrit. 2 (25.3%)Skin Sens. 1 (31.2%)Eye Dam. 1 (94.2%)Acute Tox. 3 (69.5%)Acute Tox. 4 (26.6%)Aquatic Chronic 3 (68.8%) |
| 수질 위해 등급(WGK) | 3 |
| TSCA 등재 상태 | TSCA listed |
| RTECS 번호 | GY8452000 |
| 운송 번호(UN) | UN 2733 3/PG 2 |
| 관세 코드 | 29213099 |
| 위험 문구(R) | 11-37/38-43-34-25-20 |
| 위험 표시 | F,Xi,T |
| 안전 문구(S) | 16-45-36/37/39-25-26 |
| 포장분류 | II |
| 위험 등급 | 3Acute Tox. 2 OralAcute Tox. 3 InhalationAquatic Chronic 3Eye Dam. 1Flam. Liq. 2Skin Corr. 1BSkin Sens. 1 |
| 기존화학 물질 | KE-09296 |
| F 고인화성물질 | 8-10-23 |
| 저장 분류 | 3 - Flammable liquids |
용도
용도
Cyclopentylamine acts as an important raw material and intermediate used in organic synthesis and pharmaceuticals. Further, it serves as chemokine receptor 2 antagonists. It acts as a ligand in coordination chemistry and forms cis-dichlorobis(cyclopentylamine)platinum(II) complex.
제조 및 합성 방법
제조 방법
Cyclopentylamine is produced from cyclopentanone and ammonia over nickel catalysts at 20 MPa and 150 – 200℃ in the presence of circulating hydrogen over a fixedbed catalyst.