포스페스트롤

FDA approved drugs -> Active ingredient

FDA approved drugs -> Active ingredient

SYMPTOMS: Symptoms of exposure to this compound may include liver damage and high blood pressure. It may also cause nausea, vomiting and headache. Other symptoms include mood changes, depression, nervousness, loss of appetite, dizziness, abdominal cramps, bloating, skin rash, chest pain, shortness of breath, numbness or tingling about nose and mouth, fluid accumulation, swelling and tenderness of the breasts, disturbances of vision, frequent or uncomfortable urination, painful swelling of the extremities, hepatic cutaneous prophyria, erythema nodosum, erythema multiforme, thrombophlebitis, pulmonary embolism, cerebral thrombosis, coronary thrombosis, change in body weight, loss of sex drive, post-injection flare, aggravation of migraine headaches, loss of scalp hair, hemorrhagic eruption, fatigue, backache, possible induction of neoplasia, increased incidence of gallbladder disease, breast secretion, breast enlargement, cholestatic jaundice, chloasma and melasma of the skin, hirsutism steeping of corneal curvature, intolerance to contact lenses, mental depression, chorea, reduced carbohydrate tolerance, aggravation of porphyria, edema, and transient itching and burning sensation in the perineal region.

Organophosphates, such as DIETHYLSTILBESTROL DIPHOSPHATE, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

L - Antineoplastic and immunomodulating agents

QL - Antineoplastic and immunomodulating agents

Antineoplastic agents that are used to treat hormone-sensitive tumors. Hormone-sensitive tumors may be hormone-dependent, hormone-responsive, or both. A hormone-dependent tumor regresses on removal of the hormonal stimulus, by surgery or pharmacological block. Hormone-responsive tumors may regress when pharmacologic amounts of hormones are administered regardless of whether previous signs of hormone sensitivity were observed. The major hormone-responsive cancers include carcinomas of the breast, prostate, and endometrium; lymphomas; and certain leukemias. (From AMA Drug Evaluations Annual 1994, p2079)