Phospho-L-tyrosine

HCID 30819CAS 21820-51-9
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기본 정보

표준 SMILES
N[C@@H](Cc1ccc(OP(=O)(O)O)cc1)C(=O)O
InChIKey
DCWXELXMIBXGTH-QMMMGPOBSA-N
분자식
C9H12NO6P
평균 분자량
261.17 g/mol
단동위원소 질량
261.04022373

개요

O(4)-phospho-L-tyrosine is a non-proteinogenic L-alpha-amino acid that is L-tyrosine phosphorylated at the phenolic hydroxy group. It has a role as an immunogen and an Escherichia coli metabolite. It is a L-tyrosine derivative, an O(4)-phosphotyrosine and a non-proteinogenic L-alpha-amino acid. It is a conjugate acid of an O(4)-phosphonato-L-tyrosine(2-). It is an enantiomer of an O(4)-phospho-D-tyrosine.

이름 및 식별자

우선 이름
Phospho-L-tyrosine
IUPAC
(2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid
영어명
O-Phospho-L-tyrosine
분자식
C9H12NO6P
분자량
261.17

이름 및 동의어

21820-51-9PhosphonotyrosinePHOSPHOTYROSINEPhospho-L-tyrosine2R86C98KDXDTXSID00176234L-Tyrosine, dihydrogen phosphate (ester)(2S)-2-amino-3-[4-(phosphonooxy)phenyl]propanoic acid(2S)-2-amino-3-(4-(phosphonooxy)phenyl)propanoic acidtyrosine-o-phosphateTyrosine O phosphateRefChem:863006
이름 더 보기
p-TyrH-TYR(P)-OHPhospho-TyrH-Tyr(PO3)-OHH-TYR(PO3H2)-OHL-Tyr(H2PO3)-OHH-L-Tyr(PO3H2)-OH
DTXCID9098725O-Phospho-L-tyrosineO-PhosphotyrosineH-Tyr(H2PO3)-OHL-Tyrosine-O-phosphateTyrosine O-phosphateO-phosphono-L-tyrosineL-Phosphotyrosine

데이터베이스 식별자

CAS
21820-51-9
PubChem CID
30819
DTXSID
DTXSID00176234
ChEMBL
CHEMBL286939
ChEBI
CHEBI:37788
UNII
2R86C98KDX
EC Number
891-585-9
Nikkaji
J208.898C

물성

구조 계산 물성

XLogP
-2.8
극성 표면적
130 Ų
수소 결합 공여자 수
4
수소 결합 수용자 수
7
회전 가능 결합 수
5
무거운 원자 수
17

실험 및 물리화학적 성질

Chemical ClassesBiological Agents -> Amino Acids and Derivatives
DrugsPharmaceuticals -> Listed in ZINC15
Physical Description · 2건

White solid; [Sigma-Aldrich MSDS]

Solid

Collision Cross Section149.33 Ų [M+Na-2H]- [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]

물리화학적 성질

녹는점
226 · 226-227°C
끓는 점
521.7 · 521.7±60.0 °C(Predicted)
밀도
1.591 · 1.591±0.06 g/cm3(Predicted)
저장 조건
-20 °C · Sealed in dry,Store in freezer, under -20°C
용해도
산성 용액(약간 용해됨), 물(약간 용해됨, 초음파처리)
물리적 상태
고체

화학적 성질

White Solid

안전 및 규제

GHS 분류

GHS Classification · 3건

This chemical does not meet GHS hazard criteria for 100% (2 of 2) of all reports.

Not Classified

Aggregated GHS information provided per 2 reports by companies from 1 notifications to the ECHA C&L Inventory.

유해성 정보

Regulatory InformationStatus: Active Update: 04-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/34754
Hazards SummaryMay cause irritation; [Sigma-Aldrich MSDS]
Hazard Classes and CategoriesNot Classified

안전 데이터

wgk
3
HS 번호
29225090
risk_code
21/22
hazard_code
Xn
safety_code
36/37
F 고인화성물질
10-21

화학 및 산업

용도 및 제조

UsesAmino acid found in endogenous proteins; [ChemIDplus]

응용 분야

용도O-Phospho-L-tyrosine is used in the study of tyrosine-phosphorylation, which has been linked to the malignant transformation of cells by various RNA tumor viruses. Plays a role in signal transduction.

공급사50 곳

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
南京世洲生物科技有限公司025-85560043 15850508050 · [email protected]
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖南韵邦生物科技股份有限公司85561037 15386497078 · [email protected]

추가 설명

정의ChEBI: A non-proteinogenic L-alpha-amino acid that is L-tyrosine phosphorylated at the phenolic hydroxy group.

관련 반응

3건
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