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기본 정보
- CAS
94424-50-7- 표준 SMILES
CCCN1C[C@@H](NS(=O)(=O)N(CC)CC)C[C@@H]2Cc3c(O)cccc3C[C@H]21.Cl- InChIKey
DVLKVIJLALMCBQ-MSSRUXLCSA-N- 분자식
- C20H34ClN3O3S
- 평균 분자량
- 432.03 g/mol
- 단동위원소 질량
- 431.20094063
이름 및 식별자
- 우선 이름
- Quinagolide hydrochloride
- IUPAC
- N,N-Diethyl-N'-[(3S,4aS,10aR)-6-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-3-yl]sulfuric diamide--hydrogen chloride (1/1)
- 현지명
- 퀴나골리드염산염
- 영어명
- Quinagolide hydrochloride
- 분자식
- C20H33N3O3S.ClH
- 분자량
- 432.02
이름 및 동의어
퀴나골리드염산염SDZ 205-502Norprolac HydrochlorideCV205-502 hydrochlorideQUINAGOLIDE HYDROCHLORIDEQuinagolide hydrochloride (CV205-502 hydrochloride)(3S,4aS,10aR)-3-(Diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline hydrochloriderel-N,N-Diethyl-N'-[(3R,4aR,10aS)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl]sulfaMide Hydrochloride(3α,4aα,10aβ)-N,N-Diethyl-N'- (1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl)sulfaMide Monohydrochloride(+/-)-N,N-diethyl-N'-quinolinyl>sulfamide hydrochloride
데이터베이스 식별자
- CAS
94424-50-7- PubChem CID
- 3086400
- DTXSID
DTXSID20241478
물성
물리화학적 성질
- 녹는점
- 234 · 234-236°
- 저장 조건
- -20 °C · Store at -20°C
- 용해도
- 43 mg/mL · DMSO : ≥ 43 mg/mL (99.53 mM)
- 물리적 상태
- Solid
- 색상
- White to off-white
화학 및 산업
응용 분야
개요Quinagolide is a potent and specific non-ergot dopamine D2 agonist launched in the Netherlands for the treatment of hyperprolactinemia. Quinagolide is effective in inhibiting prolactin secretion by human pituitary tumor and hyperprolactinemia in vitro and in viva A daily dose of as low as 60 pg is able to achieve a pronounced and prolonged suppressive effect on serum prolactin and growth hormone secretion. It is also effective in providing relief from associated effects such as infertility, galactorrhea, oligomenorrhea, amenorrhea, loss of IibMo and impotence. Compared with the most widely used antiprolactin, bromocriptine, quinagolide is more potent in vivo with a longer duration of action and fewer side effects. A recent study showed that acute administration of quinagolide suppresses growth hormone secretion in acromegalic patients and thus could serve as an alternative therapy in acromegaly.
용도Quinagolide is a nonergot dopamine D2-receptor agonist. Quinagolide acts as an prolactin inhibitor.
공급사27 곳
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
LGM Pharma1-(800)-881-8210 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
MedChemexpress LLC021-58955995 · [email protected]
上海喀露蓝科技有限公司18149758185 18149758185 · [email protected]
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