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기본 정보
- CAS
120225-54-9- 표준 SMILES
CCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)nc(NCCc4ccc(CCC(=O)O)cc4)nc32)[C@H](O)[C@@H]1O- InChIKey
PAOANWZGLPPROA-RQXXJAGISA-N- 분자식
- C23H29N7O6
- 평균 분자량
- 499.528 g/mol
- 단동위원소 질량
- 499.21793165
이름 및 식별자
- 우선 이름
- CGS 21680
- IUPAC
- 3-{4-[2-({6-Amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]-9H-purin-2-yl}amino)ethyl]phenyl}propanoic acid
- 영어명
- CGS 21680
- 분자식
- C23H29N7O6
- 분자량
- 499.52
이름 및 동의어
C061282Cgs-21680c2-(4-(2-Carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine2-[4-(carboxyethyl)phenylethylamino]-5'-N-ethylcarboxamidoadenosine2-[[2-[4-(2-Carboxyethyl)phenyl]ethyl]amino]-5'-ethylamino-5'-oxo-5'-deoxyadenosine2-[[2-[4-(3-Hydroxy-3-oxopropyl)phenyl]ethyl]amino]-5'-deoxy-5'-oxo-5'-(ethylamino)adenosine3-(4-(2-((6-Amino-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydro-furan-2-yl)-9H-p4-[2-[[6-Amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acidBenzenepropanoic acid, 4-[2-[[6-amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]-4-[2-[[6-Amino-9-(N-ethyl-beta-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid
데이터베이스 식별자
- CAS
120225-54-9- PubChem CID
- 3086599
- DTXSID
DTXSID6043882- ChEMBL
CHEMBL331372- ChEBI
CHEBI:73283- UNII
- T5HB1E831H
- Nikkaji
- J328.681I
물성
물리화학적 성질
- 밀도
- 1.6 · 1.60
- 저장 조건
- 2 · under inert gas (nitrogen or Argon) at 2–8 °C
- 용해도
- 3.4 mg/mL, · DMSO에 최대 3.4mg/mL, 45%(w/v) 수성 2-하이드록시프로필-β-사이클로덱스트린에 20mg/mL까지 용해됩니다.
- 물리적 상태
- 고체
- 산도 계수 (pKa)
- 4.67 · 4.67±0.10(Predicted)
화학 및 산업
응용 분야
용도CGS 21680 hydrochloride is currently used in research in studying neuronal transmission, also in respiration. CGS 21680 is commonly used to study the actions of the adenosine A2A receptor in cells and tissues. CGS 21680 HCl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor. CGS 21680C effectively increases coronary flow with an ED25 value of 1.8 nM. In hippocampal slices, CGS 21680 apis weak agonist on pre- and postsynaptic measures of electrophysiologicaJ activity.
공급사38 곳
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
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上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
湖北科乐精细化工有限公司027-59101668 19945030958 · [email protected]
Hangzhou Sage Chemical Co., Ltd.+86057186818502 13588463833 · [email protected]
欧利希（湖北）医药科技有限公司17316404525 17316404525 · [email protected]
上海梅凯科技有限公司021-68689288 15300790979 · [email protected]
武汉丰泰威远科技有限公司+86-27-8746-5837 +86-18627785180 · [email protected]
武汉丰泰威远科技有限公司027-87465837 19945049750 · [email protected]
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