기본 정보
- CAS
7456-24-8- 표준 SMILES
CC(CN1c2ccccc2Sc2ccc(S(=O)(=O)N(C)C)cc21)N(C)C- InChIKey
VWNWVCJGUMZDIU-UHFFFAOYSA-N- 분자식
- C19H25N3O2S2
- 평균 분자량
- 391.6 g/mol
- 단동위원소 질량
- 391.13881904
개요
Dimetotiazine is a member of phenothiazines.
이름 및 식별자
- 우선 이름
- 10-(2-(Dimethylamino)propyl)-N,N-dimethyl-10H-phenothiazine-2-sulfonamide
- IUPAC
- 10-[2-(dimethylamino)propyl]-N,N-dimethylphenothiazine-2-sulfonamide
- 영어명
- Dimetotiazine
- 분자식
- C19H25N3O2S2
- 분자량
- 391.557
이름 및 동의어
DimetotiazineFONAZINEDimethothiazine7456-24-8DimetotiazinaDimetotiazinum10-(2-(Dimethylamino)propyl)-N,N-dimethylphenothiazine-2-sulfonamide1FTA475ZDBDTXSID6023076Phenothiazine-2-sulfonamide, 10-(2-(dimethylamino)propyl)-N,N-dimethyl-8599 R.P.IL-6302
이름 더 보기
8599RPBayer 1483DimethodinBrn 0941549DimetothiazineDimethiotazine
10-[2-(dimethylamino)propyl]-N,N-dimethylphenothiazine-2-sulfonamideDTXCID80307610-[2-(Dimethylamino)propyl]-N,N-dimethyl-10H-phenothiazine-2-sulfonamide10-(2-(Dimethylamino)propyl)-N,N-dimethyl-10H-phenothiazine-2-sulfonamideRefChem:599591N02CX05231-229-6Dimetiotazine
데이터베이스 식별자
- CAS
7456-24-8- PubChem CID
- 3089
- DTXSID
DTXSID6023076- ChEMBL
CHEMBL346977- ChEBI
CHEBI:135616
물성
구조 계산 물성
- XLogP
- 3.8
- 극성 표면적
- 77.5 Ų
- 수소 결합 공여자 수
- 0
- 수소 결합 수용자 수
- 6
- 회전 가능 결합 수
- 5
- 무거운 원자 수
- 26
- 형식 전하
- 0
- 복잡도
- 576
물리화학적 성질
- 끓는 점
- 533.7 · 533.7±60.0 °C(Predicted)
- 밀도
- 1.1822 · 1.1822 (rough estimate)
- 굴절률
- 1.656 · 1.6560 (estimate)
- 산도 계수 (pKa)
- 8.91 · 8.91±0.50(Predicted)
화학 및 산업
약리 정보
ATC Code
N - Nervous system
QN - Nervous system
MeSH Pharmacological Classification
Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.
응용 분야
용도Serotonin inhibitor.
상·하류 제품 정보
상류 원료
공급사9 곳
LGM Pharma1-(800)-881-8210 · [email protected]
陕西缔都医药化工有限公司+86-29-87569262 +86-15003564040 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
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