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오소포름산에틸

Ethyl orthoformate

HCID 31214
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기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
108055-42-1
표준 SMILES
CCOC(OCC)OCC
InChIKey
GKASDNZWUGIAMG-UHFFFAOYSA-N
분자식
C7H16O3
평균 분자량
148.2 g/mol
단동위원소 질량
148.10994437

개요

Ethyl orthoformate appears as a clear, colorless liquid with a pungent odor. Less dense than water. Vapors heavier than air. May irritate skin and eyes. Used to make other chemicals.

이름 및 식별자

우선 이름
Ethyl orthoformate
IUPAC
diethoxymethoxyethane
현지명
오소포름산에틸
영어명
Triethyl orthoformate
분자식
C7H16O3
분자량
148.2

이름 및 동의어

Triethyl orthoformate122-51-0TriethoxymethaneETHYL ORTHOFORMATEAethonOrthoformic acid triethyl esterMethane, triethoxy-Ethyl formate(ortho)Orthomravencan ethylnatyEthane, 1,1',1''-[methylidynetris(oxy)]tris-Orthoformic acid, triethyl esterOrthoformic acid ethyl ester
이름 더 보기
에틸오르토포르메이트오소포름산에틸트리에톡시메탄,오소포름산트리에틸오쏘폼산트라이에틸에틸오르토포르메이트오쏘폼산 트라이에틸TEOForthoformateETHONEiethyl orthoforMate1,1'TEOE
108055-42-1Ethylester kyseliny orthomravenciNSC 5289Orthoformic acid, ethyl esterUN2524DTXSID8041957Orthomravencan ethylnaty [Czech]Triethylester kyseliny orthomravenci

데이터베이스 식별자

CAS
108055-42-1、122-51-0
PubChem CID
31214
DTXSID
DTXSID8041957
ChEMBL
CHEMBL1476236
UNII
355LRR361Q
EC Number
204-550-4
Nikkaji
J5.533F

물성

구조 계산 물성보충 중

XLogP
1.2
극성 표면적
27.7 Ų
수소 결합 공여자 수
0
수소 결합 수용자 수
3
회전 가능 결합 수
6
무거운 원자 수
10
형식 전하
0
복잡도
51.6

실험 및 물리화학적 성질

Chemical Classes · 2건

Other Classes -> Ethers, Other

Flammable agents - 3rd degree

SpringerMaterials PropertiesBoiling point
Flavoring AgentsEU Flavoring substances
Vapor Pressure3.86 [mmHg]
Physical Description · 3건

Ethyl orthoformate appears as a clear, colorless liquid with a pungent odor. Less dense than water. Vapors heavier than air. May irritate skin and eyes. Used to make other chemicals.

Liquid

Liquid with a sweetish odor like pine needles; [Merck Index] Clear colorless liquid with a pungent odor; [CAMEO]

물리화학적 성질

녹는점
-76 °C · -76 °C (lit.)
끓는 점
146 °C · 146 °C (lit.)
밀도
0.891 g/mL · 0.891 g/mL at 25 °C (lit.)
증기 밀도
5.11 · 5.11 (vs air)
증기압
2.9 mm · 2.9 mm Hg ( 20 °C)
굴절률
20 · n20/D 1.391(lit.)

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 1.3% (7 of 540) of reports.

Warning

H226 (98.7%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P264+P265, P280, P303+P361+P353, P305+P351+P338, P337+P317, P370+P378, P403+P235, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 540 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Warning

유해성 정보

Regulatory Information · 6건

Chemical: Ethane, 1,1',1''-[methylidynetris(oxy)]tris-

Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)

Ethane, 1,1',1''-[methylidynetris(oxy)]tris- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethane, 1,1',1''-[methylidynetris(oxy)]tris- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 27-01-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/15861

Triethyl orthoformate: Does not have an individual approval but may be used under an appropriate group standard

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

DOT LabelFlammable Liquid
Fire Hazards · 2건

Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:

· HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.

Health Hazards · 2건

Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:

화학 및 산업

용도 및 제조

Uses · 2건

Used in chemical manufacture; [CAMEO] Used in chemical synthesis, in the paints-lacquers-varnishes industry, and as a stabilizer; [IUCLID] Used to make large scale and fine chemicals; [ECHA REACH Registrations] Permitted for use as an inert ingredient in non-food pesticide products; [EPA]

Painting (Solvents) [Category: Paint]

U.S. Production2023: 100,000 - <250,000 lb
Consumer UsesDrier
Industry UsesDrier
General Manufacturing Information · 2건

All Other Chemical Product and Preparation Manufacturing

Ethane, 1,1',1''-[methylidynetris(oxy)]tris-: ACTIVE

응용 분야 · 2건

용도Triethyl orthoformate is used in Bodroux-Chichibabin aldehyde synthesis to prepare an aldehyde with one carbon higher by reacting with Grignard reagent. It is also used in the electrophilic formylation of activated aromatic species such as phenol.

일반 설명Triethyl orthoformate is a clear, colorless liquid with a pungent odor. Less dense than water. Flash point 86°F. Vapors heavier than air. May irritate skin and eyes. Used to make other chemicals.

상·하류 제품 정보

상류 원료

에틸알코올나트륨클로로포름나트륨 에톡시드Sodium ethylate solution,in ethyl alcohol

관련 반응

2,292건
반응 기록 만들기
HRID 913 반응식
HRID 913반응물로uspto-grants-1998_03
HRID 1023 반응식
HRID 1023반응물로uspto-grants-1998_03
HRID 1276 반응식
HRID 1276반응물로uspto-grants-1998_03
HRID 4265 반응식
HRID 4265반응물로uspto-grants-1988_02
HRID 5350 반응식
HRID 5350반응물로uspto-grants-1993_09
HRID 7003 반응식
HRID 7003반응물로uspto-grants-2006_08
HRID 9346 반응식
HRID 9346반응물로uspto-grants-2006_08
HRID 9359 반응식
HRID 9359반응물로uspto-grants-2006_08
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화합물 노트

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이 페이지에서기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
더보기
새 노트새 반응견적 요청하기
인화점
86 °F · 86 °F
저장 조건
Flammables area
용해도
클로로포름(약간 용해됨), 에틸아세테이트(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
액체
색상
무색의
수용성
1.35 g/L · 1.35g/L
Merck
14 · 14,6884
BRN
605384 · 605384
안정성
수분에 민감한
InChI
1S/C7H16O3/c1-4-8-7(9-5-2)10-6-3/h7H,4-6H2,1-3H3
InChIKey
GKASDNZWUGIAMG-UHFFFAOYSA-N
SMILES
CCOC(OCC)OCC
LogP
1.2 at · 1.2 at 20℃
NIST
Ethyl orthoformate(122-51-0)
EPA
Ethyl orthoformate (122-51-0)

화학적 성질

Colorless liquid; pungent odor. Highly flammable. Slightly soluble in water; soluble in alcohol, ether; decomposes in water.

· May cause toxic effects if inhaled or absorbed through skin.

Hazards Summary · 1건

A mild skin and moderate eye irritant; Dermal LD50 (rabbit) = 20 mL/kg; [RTECS] Not a skin sensitizer in guinea pig maximization study; No sensitization reactions observed in maximization test of 26 volunteers at 4% in petrolatum; [IUCLID] Safe when used as a flavoring agent in food; [EFSA] A mild skin irritant; [Sigma-Aldrich MSDS] See 1,1-Dimethoxyethane.

DOT ID and Guide2524 129
Reactive GroupEthers
Reactivity AlertsHighly Flammable
Reactivity Profile · 1건

ETHYL ORTHOFORMATE is an ether. Ethers can act as bases. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert.

DOT Hazard Classification · 4건

Ethyl orthoformate

UN2524

Class 3 Flammable and combustible liquid (49 eCFR § 173.120)

PG III: the degree of danger presented by the material is minor

Air and Water ReactionsHighly flammable. Slightly soluble in water.
Hazard Classes and Categories · 3건

Flam. Liq. 3 (98.7%)

Flammable liquids - Category 3

Flammable agents - 3rd degree

안전 및 보호

Fire FightingExcerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:
Accidental Release Measures · 2건

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

First Aid · 2건

Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:

General First Aid:

Exposure Control and Personal Protection· Wear positive pressure self-contained breathing apparatus (SCBA).
Nonfire Spill ResponseExcerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:
Isolation and Evacuation · 2건

Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:

Immediate precautionary measure

Personal Protective Equipment (PPE)Excerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:
Emergency Response Planning GuidelinesCAUTION: The majority of these products have a very low flash point. Use of water spray when fighting fire may be inefficient.

독성 정보

Toxicity DataLCLo (rat) = 4,000 ppm/8hr

안전 데이터

wgk
1
tsca
TSCA listed
rtecs
RM6475000
ridadr
UN 2524
독성
LD50 orally in rats: 7.06 g/kg (Smyth)
HS 번호
29159080
risk_code
10-36-36/38
hazard_code
Xi
safety_code
16-26-37/39-36-45-36/39
포장분류
III
위험 등급
3
기존화학 물질
KE-24297
F 고인화성물질
21
Hazard Classifications
Flam. Liq. 3
스토리지 클래스
3 - Flammable liquids
염화벤조일

하류 제품

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