2-하이드록시-N,N,N-트리메틸에탄아미늄 수산화물

Choline, hydroxide

HCID 31255CAS 123-41-1

기본 정보

표준 SMILES
C[N+](C)(C)CCO.[OH-]
InChIKey
KIZQNNOULOCVDM-UHFFFAOYSA-M
분자식
C5H15NO2
평균 분자량
121.18 g/mol
단동위원소 질량
121.11027872

이름 및 식별자

우선 이름
Choline, hydroxide
IUPAC
2-hydroxyethyl(trimethyl)azanium hydroxide
현지명
2-하이드록시-N,N,N-트리메틸에탄아미늄 수산화물
영어명
Choline hydroxide
분자식
C5H15NO2
분자량
121.18

이름 및 동의어

CHOLINE HYDROXIDE123-41-1GossypineLuridine2-Hydroxy-N,N,N-trimethylethanaminium hydroxideSinkalinSinkaline(2-Hydroxyethyl)trimethylammonium hydroxideDTXSID9047467CHOLINE, HYDROXIDETrimethyl(2-hydroxyethyl)ammonium hydroxideEthanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxide
이름 더 보기
2-하이드록시-N,N,N-트리메틸에탄아미늄수산화물2-하이드록시-N,N,N-트리메틸에탄아미늄수산화물콜린 하이드록사이드수산화콜린CHOLINECholine hydroxide solutionvidineCHOLINE BASECholine hydroxide, 45 wt.% aqueous solution, stabilized, pureSKL1388SKL1600
(beta-Hydroxyethyl)trimethylammonium hydroxideDTXCID7027467Hydroxide, CholineRefChem:125755204-625-1SincalineBursineFagine

데이터베이스 식별자

CAS
123-41-1
PubChem CID
31255
DTXSID
DTXSID9047467
ChEMBL
CHEMBL3187547
UNII
7THJ3EG9SY
EC Number
204-625-1

물성

구조 계산 물성

극성 표면적
21.2 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
2
회전 가능 결합 수
2
무거운 원자 수
8

실험 및 물리화학적 성질

Physical Description · 2건

Liquid

45% aqueous solution: Brown viscous liquid; [Acros Organics MSDS]

물리화학적 성질

녹는점
236 · 236~239℃
밀도
1.09 g/mL · 1.09 g/mL at 20 °C
증기압
28.284 hPa · 28.284hPa at 25℃
굴절률
20 · n20/D 1.4304
인화점
92 °F · 92 °F
저장 조건
2 · Inert atmosphere,2-8°C

화학적 성질

clear light yellow viscous solution

안전 및 규제

GHS 분류

GHS Classification · 5건

Danger

H314 (99.7%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation];H318 (69%): Causes serious eye damage [Danger Serious eye damage/eye irritation];H335 (20.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H373 (20.2%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P319, P321, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 352 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 4건

Chemical: Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxide

Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxide (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxide (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 24-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/5289

Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxide: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Other Safety InformationEvaluation - Chemicals that are unlikely to require further regulation to manage risks to environment
Hazards SummaryCauses convulsions and dyspnea in intravenous lethal-dose studies of mice (LD50 = 21.4 mg/kg); [RTECS] 45% aqueous solution: Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; [Acros Organics MSDS]
Hazard Classes and CategoriesSkin Corr. 1B (99.7%);Eye Dam. 1 (69%);STOT SE 3 (20.5%);STOT RE 2 (20.2%)

독성 정보

Adverse EffectsDermatotoxin - Skin burns.;Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

규제 정보

Regulatory Information · 4건

Chemical: Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxide

Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxide (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxide (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 24-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/5289

Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxide: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

안전 데이터

wgk
1
tsca
TSCA listed
rtecs
GA4025500
ridadr
UN 3286 3/PG 2
HS 번호
29231000
risk_code
34-35-43-39/23/24/25-23/24/25-10-R35

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 2건

Endogenous factors or drugs that increase the transport and metabolism of LIPIDS including the synthesis of LIPOPROTEINS by the LIVER and their uptake by extrahepatic tissues.

Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms.

용도 및 제조

U.S. Production2023: 10,000,000 - <50,000,000 lb;2022: 10,000,000 - <50,000,000 lb;2021: 25,000,000 - <40,000,000 lb;2020: 25,000,000 - <40,000,000 lb
Consumer UsesSolids separation (precipitating) agent, not otherwise specified;Intermediate
Industry UsesPlating agent;pH regulating agent;Solids separation (precipitating) agent, not otherwise specified;Intermediate
General Manufacturing Information · 2건

Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing;Computer and Electronic Product Manufacturing;All Other Chemical Product and Preparation Manufacturing;All Other Basic Organic Chemical Manufacturing;Other (requires additional information)

Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxide (1:1): ACTIVE

응용 분야

용도Choline hydroxide is used as a precursor molecule for the neurotransmitter acetylcholine, it is involved in several functions including muscle and memory muscle control. It was used as a basic catalyst for aldol condensation reactions.

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
河北创之源生物科技有限公司13012111162
上海遐瑞医药科技有限公司+86-021-61551413 · [email protected]
陕西晨明生物科技有限公司15529026321
추가 설명 · 1건

정의An amino alcohol,CH2OHCH2N(CH3)3OH. It occurswidely in living organisms as aconstituent of certain types ofphospholipids– the lecithins andsphingomyelins– and in the neurotransmitteracetylcholine. It issometimes classified as a memberof the vitamin B complex.

관련 반응

44건

연결된 노트

불러오는 중…