1-클로로-2-프로탄올

1-클로로-2-프로탄올 · 1-클로로-2-프로판올 · 2-프로판올, 1-클로로- · PROPYLENE CHLOROHYDRIN · CHLOROPROPANOL · PROPYLENE CHLOROHYDRINE · Chloro-2-propa · 1-CHLOROPROPANOL

https://huagongshe.com/ko/chemical/31370

식별자 및 물리적 특성

CAS No.	127-00-4
분자식	C3H7ClO
평균 분자량	94.54 g/mol
단동위원소 질량	94.01854252 g/mol
SMILES	CC(O)CCl
InChIKey	YYTSGNJTASLUOY-UHFFFAOYSA-N
PubChem CID	31370
ChEMBL	CHEMBL1361129
ChEBI	CHEBI:76260
EC No.	204-819-6
DTXSID	DTXSID5020285
현지명	1-클로로-2-프로탄올

화학 및 물리적 성질

XLogP	0.6
극성 표면적	20.2
수소 결합 공여자 수	1
수소 결합 수용자 수	1
회전 가능 결합 수	1
무거운 원자 수	5
형식 전하	0
복잡도	22.9
물질 분류	Other Classes -> Halogenated AlcoholsMutagens
밀도	1.115 at 68 °F (NTP, 1992) - Denser than waterwill sink1.115 @ 20 °C1.111 g/mL at 25 °C(lit.)
Color/Form	COLORLESS LIQUID
용해도	greater than or equal to 100 mg/mL at 73 °F (NTP, 1992)SOL IN WATER, ALCSOL IN ETHANOL, ETHER, CARBON TETRACHLORIDE클로로포름, 메탄올(약간)에 용해됨
인화점	125 °F (NTP, 1992)
끓는 점	259 to 261 °F at 760 mmHg (NTP, 1992)126-127 °C126-127 °C(lit.)
Decomposition	WHEN HEATED TO DECOMP, IT EMITS HIGHLY TOXIC FUMES OF /HYDROGEN CHLORIDE/.
증기 밀도	3.3 (NTP, 1992) - Heavier than airwill sink (Relative to Air)3.3 (air=1)
증기압	4.9 mmHg at 68 °F (NTP, 1992)4.9 [mmHg]4.9 mm Hg @ 20 °C
굴절률	INDEX OF REFRACTION: 1.4392 @ 20 °C/Dn20/D 1.439(lit.)
Physical Description	1-chloro-2-propanol is a clear colorless to light amber liquid with a mild non residual odor. (NTP, 1992)Colorless liquid with a faintly ethereal odor[ACGIH]
저장 조건	Flammables area
용해도	물에 용해됨
물리적 상태	투명한 액체
pKa(산도 계수)	14.09±0.20(Predicted)
색상	무색~연황색
Merck	14,7851
BRN	773653
헨리 상수	5.8×100 mol/(m3Pa) at 25℃, HSDB (2015)
안정성	안정적인. 가연성. 강한 산화제와 호환되지 않습니다.
InChI	1S/C3H7ClO/c1-3(5)2-4/h3,5H,2H2,1H3
InChIKey	YYTSGNJTASLUOY-UHFFFAOYSA-N
SMILES	CC(O)CCl
EPA	1-Chloro-2-propanol (127-00-4)

화학적 성질

colourless to light yellow liquid

안전 및 규제

GHS 분류	DangerH226 (100%): Flammable liquid and vapor [Warning Flammable liquids]P210, P233, P240, P241, P242, P243, P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 173 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.H226: Flammable liquid and vapor [Warning Flammable liquids]
규제 정보	Chemical: 2-Propanol, 1-chloro-2-Propanol, 1-chloro-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
운송 라벨(DOT)	Poison Flammable Liquid
화재 위험	This chemical is combustible. (NTP, 1992)
화재 가능성	MODERATE, WHEN EXPOSED TO HEAT OR FLAME.
건강 유해성	SYMPTOMS: This compound causes skin and eye irritation. It may also be irritating to the mucous membranes and upper respiratory tract. Other symptoms include nasal irritation, nausea, vomiting, giddiness, dizziness, incoordination, visual disturbances and coma. It may also cause hemolysis, central nervous system effects and liver and kidney damage. Coughing, confusion and unconsciousness have also been reported.
유해성 요약	Causes damage to the liver and other organs in animal feeding studiesCritical Effects: reproductivegenotoxic[ACGIH] No adverse effects on fertility in a chronic feeding study of ratsIncreased testis weights and sperm abnormalities--possible evidence of slight reproductive toxicity[NTP] General anesthetic effect in lethal dose feeding studies of guinea pigs[RTECS] An irritant of the skin, eyes, and respiratory tract[CAMEO] See 2-Chloro-1-propanol.

용도

1-Chloro-2-propanol has been used as:chemical intermediate for the manufacture of propylene oxide, a starting material for production of polyurethane polyols and propylene glycolas α,β-halohydrin standard during the enzymatic synthesis of α,β-halohydrins from gaseous alkenes

일반 설명

Clear colorless to light amber liquid with a mild non residual odor.