기본 정보
- CAS
24136-24-1- 표준 SMILES
CC(=O)NCCOC(=O)C(Oc1cccc(C(F)(F)F)c1)c1ccc(Cl)cc1- InChIKey
BJBCSGQLZQGGIQ-UHFFFAOYSA-N- 분자식
- C19H17ClF3NO4
- 평균 분자량
- 415.8 g/mol
- 단동위원소 질량
- 415.0798202
개요
Halofenate is a selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) modulator with antilipidemic activity. Halofenate also decreases fasting plasma glucose in type 2 diabetic patients, but not normoglycemic subjects.
이름 및 식별자
- 우선 이름
- Halofenate
- IUPAC
- 2-acetamidoethyl 2-(4-chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]acetate
- 현지명
- 할로페네이트
- 영어명
- HALOFENATE
- 분자식
- C19H17ClF3NO4
- 분자량
- 415.79
이름 및 동의어
HALOFENATE26718-25-2MK 185HalofenatoMK-185HalofenatumK9TZK4MNO6DTXSID9023120Benzeneacetic acid, 4-chloro-alpha-(3-(trifluoromethyl)phenoxy)-, 2-(acetylamino)ethyl esterMK185RefChem:389032DTXCID103120
이름 더 보기
할로페네이트Lipivas4-Chloro-α-[3-(trifluoromethyl)phenoxy]benzeneacetic acid 2-(acetylamino)ethyl esterBenzeneacetic acid, 4-chloro-α-[3-(trifluoromethyl)phenoxy]-, 2-(acetylamino)ethyl ester
Halofenate; Lipivas2-acetamidoethyl 2-(4-chlorophenyl)-2-[3-(trifluoromethyl)phenoxy]acetateCHEMBL456071Halofenatum [INN-Latin]Halofenato [INN-Spanish]UNII-K9TZK4MNO6Halofenate [USAN:INN:BAN]4-Chloro-alpha-[3-(trifluoromethyl)phenoxy]benzeneacetic acid 2-(acetylamino)ethyl ester
데이터베이스 식별자
- CAS
24136-24-1、26718-25-2- PubChem CID
- 33584
- DTXSID
DTXSID9023120- ChEMBL
CHEMBL456071- UNII
물성
구조 계산 물성
- XLogP
- 4.3
- 극성 표면적
- 64.6 Ų
- 수소 결합 공여자 수
- 1
- 수소 결합 수용자 수
- 7
- 회전 가능 결합 수
- 8
- 무거운 원자 수
- 28
- 형식 전하
- 0
- 복잡도
- 524
물리화학적 성질
- 끓는 점
- 551.1 · 551.1±50.0 °C(Predicted)
- 밀도
- 1.331 · 1.331±0.06 g/cm3(Predicted)
- 산도 계수 (pKa)
- 15.32 · 15.32±0.46(Predicted)
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.
Gout suppressants that act directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma.
응용 분야
용도Halofenate is a selective peroxisome proliferator-activated receptor γ (PPARγ) modulator with antidiabetic activity.
공급사1 곳
TargetMol 中国（陶术生物）400-821-0310 15002144251 · [email protected]
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