기본 정보
- CAS
27060-91-9- 표준 SMILES
O=C1CN2CCOC2(c2ccccc2F)c2cc(Cl)ccc2N1CCO- InChIKey
WMFSSTNVXWNLKI-UHFFFAOYSA-N- 분자식
- C19H18ClFN2O3
- 평균 분자량
- 376.8 g/mol
- 단동위원소 질량
- 376.0989983
개요
Flutazolam is a hemiaminal ether and an organic molecular entity.
이름 및 식별자
- 우선 이름
- Flutazolam
- IUPAC
- 10-chloro-11b-(2-fluorophenyl)-7-(2-hydroxyethyl)-3,5-dihydro-2H-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
- 영어명
- Flutazolam
- 분자식
- C19H18ClFN2O3
- 분자량
- 376.81
이름 및 동의어
flutazolam27060-91-9CoreminalFlutazolamum5G2K7O5D8SDTXSID602307210-Chloro-11b-(2-fluorophenyl)-2,3,7,11b-tetrahydro-7-(2-hydroxyethyl)oxazolo(3,2-d)(1,4)benzodiazepin-6(5H)-oneRefChem:921729DTXCID20307210-chloro-11b-(2'-fluorophenyl)-2,3,5,6,7,11b-hexahydro-7-(2''-hydroxyethyl)benzo(6,7)-1,4-diazepino(5,4-b)oxazol-6-one10-chloro-11b-(2-fluorophenyl)-7-(2-hydroxyethyl)-3,5-dihydro-2H-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one10-Chloro-11b-(o-fluorophenyl)-2,3,7,11b-tetrahydro-7-(2-hydroxyethyl)oxazolo(3,2-d)(1,4)benzodiazepin-6(5H)-one
이름 더 보기
MS-4104MS 4101Ro 7-610210-Chloro-11b-(o-fluorophenyl)-2,3,7,11b-tetrahydro-7-(2-hydroxyethyl)oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one10-Chloro-11b-(2-fluorophenyl)-2,3,7,11b-tetrahydro-7-(2-hydroxyethyl)oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-oneOxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one, 10-chloro-11b-(2-fluorophenyl)-2,3,7,11b-tetrahydro-7-(2-hydroxyethyl)-Oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one, 10-chloro-11b-(o-fluorophenyl)-2,3,7,11b-tetrahydro-7-(2-hydroxyethyl)- (8CI)
물성
구조 계산 물성
- XLogP
- 2.2
- 극성 표면적
- 53 Ų
- 수소 결합 공여자 수
- 1
- 수소 결합 수용자 수
- 5
- 회전 가능 결합 수
- 3
- 무거운 원자 수
- 26
- 형식 전하
- 0
- 복잡도
- 539
실험 및 물리화학적 성질
DrugsPharmaceuticals -> Nervous system -> Anxiolytics
물리화학적 성질
- 녹는점
- 142 · 142-147°
- 끓는 점
- 601.9 · 601.9±55.0 °C(Predicted)
- 밀도
- 1.297 · 1.2970 (estimate)
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨, 초음파처리)
- 물리적 상태
- 고체
- 산도 계수 (pKa)
- 5.4 · 5.40(at 25℃)
- 색상
- 흰색에서 연한 노란색
화학 및 산업
응용 분야
개요Flutazolam is a benzodiazepine anxiolytic closely related to mexazolam. It is useful in the treatment of anxiety, stress and depression in hypersensitive colon syndrome, chronic gastritis, and gastric and duodenal ulcers.
공급사5 곳
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
艾吉析科技（上海）有限公司17717235263 17717235263 · [email protected]
Henan Bao Enluo International TradeCo.，LTD+86-17331933971 · [email protected]
Xiamen Wonderful Bio Technology Co., Ltd.+86-13043004613 · [email protected]
Wuhan Han Sheng New Material Technology Co.，Ltd+86-17798174412 · [email protected]
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