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기본 정보
- CAS
1146-04-9- 표준 SMILES
CC1=C2C(=CC(C)(C)[C@@H]2O)C(=O)[C@](C)(O)C12CC2- InChIKey
QVMDIQLUNODCTG-OCCSQVGLSA-N- 분자식
- C15H20O3
- 평균 분자량
- 248.322 g/mol
- 단동위원소 질량
- 248.1412445
이름 및 식별자
- 우선 이름
- Illudin M
- 현지명
- 일루딘M
- 영어명
- illudin M
- 분자식
- C15H20O3
- 분자량
- 248.32
이름 및 동의어
일루딘Milludin M(3S)-2,3-Dihydro-3α,6β-dihydroxy-2,2,4,6-tetramethylspiro[5H-indene-5,1'-cyclopropan]-7(6H)-one(3'S,6'R)-2',3'-Dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one(3'S,6'R)-3',6'-dihydroxy-2',2',4',6'-tetramethyl-2',3',6',7'-tetrahydrospiro[cyclopropane-1,5'-inden]-7'-oneSpiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one, 2',3'-dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethyl-, (3'S,6'R)-
데이터베이스 식별자
- CAS
1146-04-9- PubChem CID
- 344199
- DTXSID
DTXSID801031276- ChEMBL
CHEMBL501342- ChEBI
CHEBI:5866- UNII
- 0ASO6A4L61
- Nikkaji
- J17.224C
물성
물리화학적 성질
- 녹는점
- 120 · 120-122.5° (Matsumoto); mp 128-130° (McMorris)
- 끓는 점
- 452.4 · 452.4±45.0 °C(Predicted)
- 밀도
- 1.24 · 1.24±0.1 g/cm3(Predicted)
- 저장 조건
- -20 °C · Store at -20°C
- 용해도
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- 물리적 상태
- 고체
- 산도 계수 (pKa)
- 12.57 · 12.57±0.70(Predicted)
- 색상
- Off-white to light yellow
- InChI
- InChI=1S/C15H20O3/c1-8-10-9(7-13(2,3)12(10)17)11(16)14(4,18)15(8)5-6-15/h7,12,17-18H,5-6H2,1-4H3/t12-,14+/m1/s1
- InChIKey
- QVMDIQLUNODCTG-OCCSQVGLSA-N
- SMILES
- C12([C@](O)(C)C(=O)C3C(=C1C)[C@@H](O)C(C)(C)C=3)CC2
화학 및 산업
응용 분야
개요Illudin M is a cytotoxic sesquiterpene from the fungus O. illudens that alkylates DNA. It is cytotoxic to HL-60 human leukemia cells at 6-100 nM. Illudin M was used as a base structure for the development of potential anticancer agents with less toxicity and improved efficacy. It is closely related to illudin S , which has been the focus of additional studies.
용도Illudin M is a cytotoxic sesquiterpene from Omphalotus illudens and Granulobasidium vellereum. It acts as an alkylating agent that can cause inhibition of cell growth or replication.
공급사38 곳
武汉敬康恩生物医药科技有限公司13720134139 086-15871494362 13720134139 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
上海遐瑞医药科技有限公司+86-021-61551413 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]
苏州五月六进出口贸易有限公司17715515539 · [email protected]
上海赛可锐生物科技有限公司021-58000709 13120558703 · [email protected]
Nantong HI-FUTURE Biology Co., Ltd.+86-18051384581 · [email protected]
湖南瑞威尔生物科技有限公司18627957289 18173226957 · [email protected]
江西瑞威尔生物科技有限公司18502728206 · [email protected]
孟成科技（上海）有限公司
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