헥사플루오레늄

헥사플루오레늄 · 9H-fluoren-9-yl-[6-[9H-fluoren-9-yl(dimethyl)azaniumyl]hexyl]-dimethylazanium

식별자 및 물리적 특성

CAS No.	4844-10-4
분자식	C36H42N2+2
평균 분자량	502.7 g/mol
단동위원소 질량	502.33479935 g/mol
SMILES	C[N+](C)(CCCCCC[N+](C)(C)C1c2ccccc2-c2ccccc21)C1c2ccccc2-c2ccccc21
InChIKey	HDZAQYPYABGTCL-UHFFFAOYSA-N
PubChem CID	3601
ChEMBL	CHEMBL1201349
ChEBI	CHEBI:135804
DTXSID	DTXSID00859333
현지명	헥사플루오레늄

화학 및 물리적 성질

XLogP	7.6
극성 표면적	0
수소 결합 공여자 수	0
수소 결합 수용자 수	0
회전 가능 결합 수	9
무거운 원자 수	38
형식 전하	2
복잡도	663
의약품	Pharmaceuticals -> Listed in ZINC15
녹는점	Crystals from n-propanolMP: 188-189 °C /Hexafluorenium bromide/

안전 및 규제

FDA 요건	Manufacturers, packers, and distributors of drug and drug products for human use are responsible for complying with the labeling, certification, and usage requirements as prescribed by the Federal Food, Drug, and Cosmetic Act, as amended (secs 201-902, 52 Stat. 1040 et seq., as amended21 U.S.C. 321-392).
처리 방법	SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
상호 작용	CONSISTENT WITH ITS STABILIZING ACTION, IT POTENTIATES NEUROMUSCULAR BLOCKADE BY TUBOCURARINE & ANTAGONIZES THAT BY DECAMETHONIUM, BUT ITS EFFECTS ON BLOCKADE BY GALLAMINE ARE ERRATIC. PARADOXICALLY, IT MARKEDLY POTENTIATES & PROLONGS NEUROMUSCULAR ACTIONS OF SUCCINYLCHOLINE. /HEXAFLUORENIUM BROMIDE/INTERACTION OF HEXAFLUORENIUM BROMIDE WITH ACETYLCHOLINE IODIDE, CARBACHOL & SUXAMETHONIUM CHLORIDE WITH REGARD TO DEPOLARIZATION OF THE END-PLATE OF RAT DIAPHRAGM WAS STUDIED.
Human Toxicity Excerpts	POISONING FROM NEUROMUSCULAR BLOCKING AGENTS IS ALMOST ALWAYS RESULT OF CLINICAL OVERDOSAGE OR THEIR INJUDICIOUS USE. IMPORTANT UNTOWARD RESPONSES ARE PROLONGED APNEA, CARDIOVASCULAR COLLAPSE, & THOSE RESULTING FROM HISTAMINE RELEASE. /NEUROMUSCULAR BLOCKING AGENTS/
유해 물질 데이터	4844-10-4(Hazardous Substances Data)

식별자 및 물리적 특성

CAS No.

4844-10-4

분자식

C36H42N2+2

평균 분자량

502.7 g/mol

단동위원소 질량

502.33479935 g/mol

SMILES

C[N+](C)(CCCCCC[N+](C)(C)C1c2ccccc2-c2ccccc21)C1c2ccccc2-c2ccccc21

InChIKey

HDZAQYPYABGTCL-UHFFFAOYSA-N

PubChem CID

3601

ChEMBL

CHEMBL1201349

ChEBI

CHEBI:135804

DTXSID

DTXSID00859333

현지명

헥사플루오레늄

XLogP

7.6

극성 표면적

수소 결합 공여자 수

수소 결합 수용자 수

회전 가능 결합 수

무거운 원자 수

형식 전하

복잡도

663

의약품

Pharmaceuticals -> Listed in ZINC15

녹는점

Crystals from n-propanolMP: 188-189 °C /Hexafluorenium bromide/

안전 및 규제

FDA 요건

Manufacturers, packers, and distributors of drug and drug products for human use are responsible for complying with the labeling, certification, and usage requirements as prescribed by the Federal Food, Drug, and Cosmetic Act, as amended (secs 201-902, 52 Stat. 1040 et seq., as amended21 U.S.C. 321-392).

처리 방법

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

상호 작용

CONSISTENT WITH ITS STABILIZING ACTION, IT POTENTIATES NEUROMUSCULAR BLOCKADE BY TUBOCURARINE & ANTAGONIZES THAT BY DECAMETHONIUM, BUT ITS EFFECTS ON BLOCKADE BY GALLAMINE ARE ERRATIC. PARADOXICALLY, IT MARKEDLY POTENTIATES & PROLONGS NEUROMUSCULAR ACTIONS OF SUCCINYLCHOLINE. /HEXAFLUORENIUM BROMIDE/INTERACTION OF HEXAFLUORENIUM BROMIDE WITH ACETYLCHOLINE IODIDE, CARBACHOL & SUXAMETHONIUM CHLORIDE WITH REGARD TO DEPOLARIZATION OF THE END-PLATE OF RAT DIAPHRAGM WAS STUDIED.

Human Toxicity Excerpts

POISONING FROM NEUROMUSCULAR BLOCKING AGENTS IS ALMOST ALWAYS RESULT OF CLINICAL OVERDOSAGE OR THEIR INJUDICIOUS USE. IMPORTANT UNTOWARD RESPONSES ARE PROLONGED APNEA, CARDIOVASCULAR COLLAPSE, & THOSE RESULTING FROM HISTAMINE RELEASE. /NEUROMUSCULAR BLOCKING AGENTS/

유해 물질 데이터

4844-10-4(Hazardous Substances Data)