Hexamethylene Bisacetamide

HCID 3616CAS 3073-59-4

기본 정보

표준 SMILES
CC(=O)NCCCCCCNC(C)=O
InChIKey
BNQSTAOJRULKNX-UHFFFAOYSA-N
분자식
C10H20N2O2
평균 분자량
200.28 g/mol
단동위원소 질량
200.15247788

개요

N-(6-acetamidohexyl)acetamide is a member of acetamides.

이름 및 식별자

우선 이름
Hexamethylene Bisacetamide
IUPAC
N-(6-acetamidohexyl)acetamide
영어명
Hexamethylene bisacetamide
분자식
C10H20N2O2
분자량
200.28

이름 및 동의어

3073-59-4Hexamethylene bisacetamideHexamethylenebisacetamideN,N'-HexamethylenebisacetamideHexamethylenediacetamidediacetyldiaminohexaneNSC-95580ACETAMIDE, N,N'-HEXAMETHYLENEBIS-NSC 95580N,N'-diacetyl-1,6-hexanediamineN,N'-1,6-HexanediylbisacetamideNSC95580
이름 더 보기
N,N'-(Hexane-1,6-diyl)diacetamideN,N′1,6-DIACETAMIDOHEXANE1,6-HexanebisacetamideHEXAMETHYLENE BISCETAMIDE
LA133J59VUDTXSID2041044N, N'-DiacetylhexamethylenediamineAcetamide, N,N'-1, 6-hexanediylbis-N-{6-[(1-hydroxyethylidene)amino]hexyl}ethanimidic acidhexamethylen bisacetamideN-(6-((1-hydroxyethylidene)amino)hexyl)ethanimidic acidRefChem:786209

데이터베이스 식별자

CAS
3073-59-4
PubChem CID
3616
DTXSID
DTXSID2041044
ChEMBL
CHEMBL291481
ChEBI
CHEBI:125472
UNII
LA133J59VU
Nikkaji
J227.810C

물성

구조 계산 물성

XLogP
0.3
극성 표면적
58.2 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
2
회전 가능 결합 수
7
무거운 원자 수
14

실험 및 물리화학적 성질

Solubility · 6건

H2O > 50 (mg/mL)

pH 4 Acetate buffer > 50 (mg/mL)

pH 9 Carbonate buffer > 50 (mg/mL)

0.1 N NaOH > 50 (mg/mL)

0.1 N HCL > 50 (mg/mL)

10% Ethanol > 50 (mg/mL)

Stability/Shelf Life · 1건

Bulk: A sample stored at 60°C in the dark for 30 days retained 99 2% of its potency (GC). Solution: Samples were dissolved in water at a concentration of 20 mg/mL and stored in clear glass containers at room temperatures under normal laboratory light for 9 days. The sample retained 98 2% of its potency (GC).

물리화학적 성질

녹는점
128 · 128-129 °C(lit.)
끓는 점
338.01 °C · 338.01°C (rough estimate)
밀도
0.974 · 0.974
굴절률
1.471 · 1.4710 (estimate)
저장 조건
Sealed in dry,Room Temperature
용해도
5 %, · 물: 가용성 5%, 투명, 무색

화학적 성질

white crystalline powder or flakes

안전 및 규제

안전 데이터

wgk
3
rtecs
AC2976200
독성
human,TDLo,intravenous,4270mg/kg/10D (4270mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGBLOOD: THROMBOCYTOPENIA,Cancer Research. Vol. 47, Pg. 5788, 1987.
HS 번호
29241990
risk_code
33
safety_code
22-24/25

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 2건

Substances that inhibit or prevent the proliferation of NEOPLASMS.

Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias.

응용 분야

용도N,N′-Hexamethylene bis(acetamide) was used as an inducing agent in obtaining mononuclear cells from the peripheral blood (PB) sample by Ficoll-Hypaque gradient separation.

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
上海莉凯化工技术有限公司16628776521 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]

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