기본 정보
- CAS
14918-35-5- 표준 SMILES
CNC1CC(N)C(O)C(OC2OC(CO)C(O)C3OC4(OC(C(N)CO)C(O)C(O)C4O)OC23)C1O- InChIKey
GRRNUXAQVGOGFE-UHFFFAOYSA-N- 분자식
- C20H37N3O13
- 평균 분자량
- 527.5 g/mol
- 단동위원소 질량
- 527.23263824
개요
Destomysin is an amino cyclitol.
이름 및 식별자
- 우선 이름
- Destomysin
- IUPAC
- 4-[3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy-6'-(1-amino-2-hydroxyethyl)-6-(hydroxymethyl)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,2'-oxane]-3',4',5',7-tetrol
- 영어명
- destomycin A
- 분자식
- C20H37N3O13
- 분자량
- 527.52
이름 및 동의어
DestomysinHygrovetineHygrovectineHyanthelmixHygromycinBC20H37N3O13Hygromycin B from Streptomyces hygroscopicusCHEBI:4454SCHEMBL18763320D-Streptamine, O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1.fwdarw.2-3)-O-.beta.-D-talopyranosyl-(1.fwdarw.5)-2-deoxy-N1-methyl-s29084-[3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy-6'-(1-amino-2-hydroxyethyl)-6-(hydroxymethyl)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,2'-oxane]-3',4',5',7-tetrol
이름 더 보기
DestoMycinDESTONATEDestonate 20destomycin ADestonmycin A5)-2-deoxy-N1-methyl-destomycin A USP/EP/BP2-3)-O-b-D-talopyranosyl-(1®D-Streptamine,O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1®D-Streptamine, O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1→2-3)-O-β-D-talopyranosyl-(1→5)-2-deoxy-N1-methyl-
CID 23777801DB-068433Hygromycin B from Streptomyces hygroscopicus powderQ271063884-[3-amino-2,6-dihydroxy-5-(methylamino)cyclohexoxy]-6'-(1-amino-2-hydroxy-ethyl)-6-(hydroxymethyl)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,2'-tetrahydropyran]-3',4',5',7-tetrolD-Stretamine,3-O-[6-(1-amino-2-hydroxyethyl)tetrahydro-3,4,5-trihydroxy-2H-pyran-2-ylidene)-.beta.-D-talopyranosyl]-2-deoxy-N(sup3)methyl-
물성
구조 계산 물성
- XLogP
- -6.6
- 극성 표면적
- 272 Ų
- 수소 결합 공여자 수
- 11
- 수소 결합 수용자 수
- 16
- 회전 가능 결합 수
- 6
- 무거운 원자 수
- 36
- 형식 전하
- 0
- 복잡도
- 756
실험 및 물리화학적 성질
Melting Point160 - 180 °C
Physical DescriptionSolid
물리화학적 성질
- 녹는점
- 180 · 180-190° (dec)
- 끓는 점
- 608.13 °C · 608.13°C (rough estimate)
- 밀도
- 1.4252 · 1.4252 (rough estimate)
- 굴절률
- 1.63 · 1.6300 (estimate)
- 산도 계수 (pKa)
- 12.53 · 12.53±0.10(Predicted)
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- 독성
- LD50 in mice (after 2-week observation) (mg/kg): 5-10 i.v.; 50-100 orally (Kondo, 1965)
화학 및 산업
약리 정보
Cellular LocationsCytoplasm
응용 분야
개요Destomycin A was found in the culture broth of Streptomyces rimofaciens by Meiji Seika Kaisha in 1965 in the course of screening for water-soluble and basic antibiotics, such as aminoglycosides. It shows activity against a variety of gram-positive and gram-negative bacteria as well as fungi and, more interestingly, against helminths. Destomycin A has been used to treat helminth infections in swine and poultry.
상·하류 제품 정보
상류 원료
공급사14 곳
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd+86-13119157289 · [email protected]
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上海倍卓生物科技有限公司021-61119791,13386096464 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
HANGZHOU LEAP CHEM CO., LTD.
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