기본 정보
- 표준 SMILES
NN=O- InChIKey
XKLJHFLUAHKGGU-UHFFFAOYSA-N- 분자식
- H2N2O
- 평균 분자량
- 46.029 g/mol
- 단동위원소 질량
- 46.01671269
이름 및 식별자
- 우선 이름
- Nitrosamine
- IUPAC
- nitrous amide
- 현지명
- 니트로사민
- 영어명
- Nitrosamine
- 분자식
- H2N2O
- 분자량
- 46.03
이름 및 동의어
Nitrosaminenitrous amideNitrosamide35576-91-1N-NITROSAMINELGB75A6POHNSC-223080DTXSID2074037NSC223080RefChem:166119DTXCID6039053CHEBI:35803
이름 더 보기
니트로사민NitsoamideNitrosoamineNitrosamide (8CI,9CI)35576-91-1---NitrosamineBenserazide Impurity 11 (Nitrosamine)
hydroxydiazeneHYDROXYDIIMIDENITROXYLAMIDEketohydrazineHydroxydiiminediazene-N-oxideNSC 223080UNII-LGB75A6POH
데이터베이스 식별자
- CAS
35576-91-1- PubChem CID
- 37183
- DTXSID
DTXSID2074037- UNII
- LGB75A6POH
- Nikkaji
- J332.210F
물성
구조 계산 물성
- XLogP
- -0.6
- 극성 표면적
- 55.5 Ų
- 수소 결합 공여자 수
- 1
- 수소 결합 수용자 수
- 3
- 회전 가능 결합 수
- 0
- 무거운 원자 수
- 3
- 형식 전하
- 0
- 복잡도
- 10
물리화학적 성질
- 녹는점
- 62 °C · 62 °C
- 끓는 점
- 191 · 191-195 °C
- 밀도
- 1.53 · 1.53±0.1 g/cm3(Predicted)
- 산도 계수 (pKa)
- -4.2 · -4.20±0.70(Predicted)
- EPA
- Nitrosamine (35576-91-1)
안전 및 규제
유해성 정보
Hazards Summary
The acute toxicity of the dialkylnitrosamines decreases with increasing chain length. [ACGIH] Appreciation of the carcinogenicity of the nitrosamines has led to their characterization in many occupational and environmental circumstances. N-nitrosodimethylamine (NDMA) has caused fatal hepatic necrosis after acute exposure and liver cirrhosis after chronic exposure. [LaDou, p. 507-8]
Reactive GroupNitro, Nitroso, Nitrate, and Nitrite Compounds, Organic
Reactivity AlertsStrong Oxidizing Agent
Reactivity ProfileNitrated organics, such as NITROSAMINES, range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction.
Air and Water ReactionsNo rapid reaction with air. No rapid reaction with water.
독성 정보
Adverse EffectsOccupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.
화학 및 산업
용도 및 제조
Uses
Nitrosamines are produced in foundry, tanning, and rubber manufacturing processes. Nitrosamines are carcinogens in experimental animals. [Hawley] Sources of exposure include cigarette smoking, cured or smoked meat and fish, metalworking fluids, rubber vulcanization, leather tanning, and endogenous nitrosation of drugs in the stomach. [Rom, p. 1229-31]
Metal Preparation and Pouring [Category: Foundry]；Metal Machining [Category: Heat or Machine]；Leather Tanning and Processing [Category: Industry]
Smoking cigarettes [Category: Food & Drugs]
공급사6 곳
泰州市众致生物科技有限公司[email protected] 15066129350 · [email protected]
金瓯生物医药（南京）有限公司13000000000 · [email protected]
深圳振强药物研发有限公司+86-0755-66853366 +86-13670046396 · [email protected]
河南誉康卓宁进出口有限公司13393721940 · [email protected]
Shaanxi Didu New Materials Co. Ltd+86-86-17392712779 +86-13289823923 · [email protected]
河南天孚化工有限公司+86-0371-55170693 +86-19937530512 · [email protected]
관련 반응
4건
연결된 노트
불러오는 중…