4-(4-Chlorophenyl)-4-hydroxypiperidine (HCID 38282)

개요

4-(4-chlorophenyl)-4-hydroxypiperidine is a member of piperidines.

이름 및 식별자

우선 이름: 4-(4-Chlorophenyl)-4-hydroxypiperidine
IUPAC: 4-(4-chlorophenyl)piperidin-4-ol
현지명: 4-(4-염화페닐)-4-히드록시피페리딘
영어명: 4-(4-Chlorophenyl)piperidin-4-ol
분자식: C11H14ClNO
분자량: 211.69

이름 및 동의어

39512-49-74-(4-Chlorophenyl)-4-hydroxypiperidine4-(4-CHLOROPHENYL)-4-PIPERIDINOLUND92FKS0WDTXSID70577334-(4'-Chlorophenyl)-4-piperidinolNSC-89568DTXCID8031522RefChem:513427254-479-84-(4-chlorophenyl)piperidin-4-olLoperamide EP Impurity C

이름 더 보기

4-(4-염화페닐)-4-히드록시피페리딘4-(4-클로로페닐)-4-하이드록시피페리딘4-(4-클로로페닐)-4-하이드록시피페리딘(4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDIN...4-(4-클로로페닐)피페리딘-4-올Loperamide Impurity CNSC 89568Compound Fr13199NMDAR antagonist 3TIMTEC-BB SBB003427LABOTEST-BB LT00233227HALOPERIDOL METABOLITE I4-(4-Chlorophenyl)-4-hydroxy

4-Piperidinol, 4-(4-chlorophenyl)-MFCD000060014-(p-Chlorophenyl)-4-hydroxypiperidine4-(p-Chlorophenyl)piperidin-4-ol4-(Chlorophenyl)-4-hydroxylpiperidineEINECS 254-479-84-Hydroxy-4-(p-chlorophenyl)piperidine4-Hydroxy-4-(4-chlorophenyl)piperidine

데이터베이스 식별자

CAS: 39512-49-7
PubChem CID: 38282
DTXSID: DTXSID7057733
ChEMBL: CHEMBL3298755
ChEBI: CHEBI:169225
UNII: UND92FKS0W
EC Number: 254-479-8
Nikkaji: J31.368H

물성

구조 계산 물성

XLogP: 1.6
극성 표면적: 32.3 Å²
수소 결합 공여자 수: 2
수소 결합 수용자 수: 2
회전 가능 결합 수: 1
무거운 원자 수: 14
형식 전하: 0
복잡도: 184

실험 및 물리화학적 성질

Chemical ClassesNitrogen Compounds -> Other Aromatics (Nitrogen)

LogP1.98

Physical DescriptionOff-white powder; [Alfa Aesar MSDS]

물리화학적 성질

녹는점: 137 · 137-140 °C (lit.)
끓는 점: 344.5 · 344.5±42.0 °C(Predicted)
밀도: 1.1138 · 1.1138 (rough estimate)
굴절률: 1.6 · 1.6000 (estimate)
저장 조건: Keep in dark place,Sealed in dry,Room Temperature
용해도: 340 mg/L · 340mg/L
물리적 상태: 결정성 분말
산도 계수 (pKa): 13.92 · 13.92±0.20(Predicted)
색상: 흰색에서 크림색을 띠는 흰색
수소이온지수(pH): 10 · 10 (H2O, 20℃)(saturated solution)
수용성: 340 mg/L · 340mg/L(20℃)
BRN: 165923 · 165923
InChI: 1S/C11H14ClNO/c12-10-3-1-9(2-4-10)11(14)5-7-13-8-6-11/h1-4,13-14H,5-8H2
InChIKey: LZAYOZUFUAMFLD-UHFFFAOYSA-N
SMILES: OC1(CCNCC1)c2ccc(Cl)cc2
NIST: 4 · 4-(Para-chlorophenyl)-4-hydroxypiperidine(39512-49-7)

화학적 성질

white to creamy-white crystalline powder

안전 및 규제

GHS 분류

GHS Classification · 4건

Warning

H302 (28.1%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 57 reports by companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 2건

Status: Active Update: 27-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/20416

4-(4-Chlorophenyl)-4-hydroxypiperidine: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryCauses analgesia in acute subcutaneous studies of mice; [RTECS] A skin and strong eye irritant; Harmful by ingestion; [Alfa Aesar MSDS]

Hazard Classes and CategoriesAcute Tox. 4 (28.1%)

안전 데이터

wgk: 3
HS 번호: 29333999
risk_code: 36/37/38-22
hazard_code: Xi,Xn
safety_code: 26-37/39-36
위험 등급: IRRITANT
기존화학 물질: KE-05862
Hazard Classifications: Acute Tox. 4 OralAquatic Chronic 3Eye Dam. 1Skin Irrit. 2Skin Sens. 1
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

약리 정보

Metabolism/MetabolitesCPHP is a known human metabolite of reduced_haloperidol.

Tissue LocationsKidney

Cellular LocationsCytoplasm

용도 및 제조

UsesN-dealkylated model of haloperidol. [ChemIDplus]

응용 분야

용도4-(4-Chlorophenyl)-4-hydroxypiperidine can be used as potential fluorescent sigma receptor probes.

상·하류 제품 정보

상류 원료

4-브로모피페리딘브롬화수소산염 Acetate 1,2,3,6-테트라하이드로피리딘 물 브롬화수소 염화 암모늄 4-(4-클로로페닐)-4-브로모피페리드 1-벤질-2-피페리돈 1-벤질-4-(p-클로로페닐)-4-피페리디놀 4-(4-클로로페닐)피페리딘 1-N-BOC-4-(4-클로로페닐)-4-하이드록시피페리딘 4-CHLOROPHENYLMAGNESIUM BROMIDE

하류 제품

로퍼라미드 하이드로클로라이드 4-(4-클로로페닐)-4-하이드록시-a,a-디페닐-1-피페리딘부탄니트릴

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

济南百隆化学有限公司[email protected] · [email protected]

广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]

연결된 노트

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4-(4-염화페닐)-4-히드록시피페리딘

기본 정보

개요